- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Chronic Kidney Disease and Diabetes
- Cardiac Imaging and Diagnostics
- Acute Kidney Injury Research
- Dialysis and Renal Disease Management
- Coronary Interventions and Diagnostics
- Cardiac Health and Mental Health
- Biomarkers in Disease Mechanisms
- Global Health Care Issues
- Bone Metabolism and Diseases
- Sepsis Diagnosis and Treatment
- Retirement, Disability, and Employment
- Employment and Welfare Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Alcohol Consumption and Health Effects
- HIV/AIDS Impact and Responses
- Bipolar Disorder and Treatment
- Cardiac Arrest and Resuscitation
- Poverty, Education, and Child Welfare
- Electrolyte and hormonal disorders
- NF-κB Signaling Pathways
- Cardiovascular Issues in Pregnancy
Universidade do Porto
2010-2020
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2017-2020
Instituto de Saúde
2017-2020
Hospital de São João
2014-2015
St. James's Hospital
2015
Departamento de Epidemiología
2014
Objectives Prompt diagnosis of acute coronary syndrome (ACS) remains a challenge, with presenting symptoms affecting the algorithm and, consequently, management and outcomes. This study aimed to identify sex differences in ACS. Design Data were collected within prospective cohort (EPIHeart). Setting Patients confirmed type 1 (primary spontaneous) ACS who consecutively admitted Cardiology Department two tertiary hospitals Portugal between August 2013 December 2014. Participants Presenting 873...
Adherence to medication is crucial improve clinical outcomes in patients with heart failure (HF). However, at least 1 out of 4 nonadherent his or her medication. Several studies have quantified adherence HF patients, monitoring only drug the Medication Event Monitoring System (MEMS). Some authors argued that reflects whole behavior, although there some evidence important differences distinct classes. Furthermore, characteristics could be a relevant predictor adherence, and different drugs...
Monitoring food consumption and its determinants over time is essential for defining implementing health promotion strategies, but surveillance scarce in Africa. The present study aimed to describe fruit vegetable Mozambique according socio-demographic characteristics place of residence (urban/rural). A national representative sample ( n 3323) subjects aged 25–64 years was evaluated 2005 following the WHO Stepwise Approach Chronic Disease Risk Factor Surveillance, which included an...
Early reperfusion for patients with ST-segment elevation myocardial infarction (STEMI) is indicated by the European Society of Cardiology, while a timely invasive strategy recommended high-risk and intermediate-risk non-ST-elevation acute coronary syndromes (NSTE-ACS). This study aims to assess patient system delays according diagnosis risk profile, identify predictors prolonged delay. We assembled cohort (n=939) consecutively admitted cardiology department two hospitals, one in metropolitan...
Aims Obesity and diabetes are associated with an increased cardiovascular risk mortality. Paradoxically, higher BMI is longer survival in heart failure patients. The association between of death patients depends on history. Methods We conducted a retrospective cohort study 503 ambulatory systolic attending clinic, based abstraction data from clinical records. Patients were compared according to was analyzed as continuous variable dichotomized using 25 kg/m2 cut-off. Patients' follow-up...
Real-world data from different levels of hospital specialisation would help to understand if differences in management between women and men with acute coronary syndrome (ACS) are still a priority target. We aimed identify sex inequalities patients types ACS.We analysed 1757 non-ST-elevation ACS (NSTEACS) 1184 ST elevation myocardial infarction (STEMI) or left bundle branch block (non-classifiable (NC) (STEMI/NC group), consecutively discharged ten Portuguese hospitals levels, 2008 2010....
Objectives To estimate cardiac rehabilitation (CR) referral and participation rates among patients with acute coronary syndrome (ACS) to identify their determinants, in two Portuguese regions. Design Prospective cohort study. Setting Patients consecutively admitted the cardiology department of hospitals, one district Porto north-east region (NER) Portugal, were enrolled EPIHeart then followed up for 6 months. Participants Between August 2013 December 2014, 939 included cohort, 853...
Patients with acute kidney injury (AKI) are at risk for increased morbidity and mortality. Lack of specific treatment has meant that efforts have focused on early diagnosis timely treatment. Advanced algorithms clinical assistance including AKI prediction models potential to provide accurate estimates. In this project, we aim a decision supporting system (CDSS) based self-learning predictive model in patients an care hospital. Data all in-patient episodes adults admitted will be analysed...
Estimates of the burden ischemic heart disease (IHD), including geographic differences, should support health policy decisions. We set out to estimate IHD in mainland Portugal 2013 by calculating disability-adjusted life years (DALYs) and compare this between five regions. Years lost (YLLs) were calculated multiplying number deaths (Statistics Portugal) expectancy at age which death occurred. lived with disability (YLDs) computed as cases acute coronary syndrome, stable angina failure...
Aim Validation of the Seattle Heart Failure Model (SHFM) for predicting risk death in a population different than derivation cohort. Methods In retrospective analysis cohort chronic heart failure patients with left ventricular systolic dysfunction, consecutively referred between 2000 and 2011, we computed score, according to characteristics at referral. We compared observed that predicted by model, using receiver operating characteristic (ROC) curves assess discrimination goodness-of-fit...
Fluctuations in serum creatinine (SCr) during hospitalization may provide additional prognostic value beyond baseline renal function. This study aimed to identify groups of patients with distinct trajectories over hospital stay and assess them terms clinical characteristics short-term mortality. retrospective included 35 853 unique adult admissions a tertiary referral center between January 2012 2016 at least three SCr measurements within the first 9 days stay. Individual courses were...
<b><i>Introduction:</i></b> In hospitalized patients, information on preadmission kidney function is often missing, impeding timely and accurate acute injury (AKI) detection affecting results of AKI-related studies. <b><i>Objective:</i></b> this study, we provided estimates serum creatinine (SCr), based a multivariate linear regression (Model 1) random forest model 2) built with different parametrizations. Their accuracy for AKI diagnosis was...
The aim of this study was to assess the proportion patients with a first episode acute coronary syndrome (ACS) reporting preceding chest pain, having previously sought medical care and undergone performance exams, identify determinants seeking advice undergoing electrocardiogram (ECG).Within cohort study, 690 ACS were evaluated. A questionnaire applied pain within 6 months event health system resources utilization. Determinants identified by logistic regression.Preceding reported 61%...
Abstract Background: Modifications in Jaffe serum creatinine (sCr) assays question the suitability of results for direct comparison. Methods: sCr adult in-patients was routinely measured either by SRM 909-standardized/noncompensated (method A) or isotope dilution mass spectrometry traceable/compensated method (reference). We converted values A into reference using a formula provided manufacturer [Beckman Coulter (BC)] and traditional equating methods. Results: The BC-based conversion linear...