- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Antibiotics Pharmacokinetics and Efficacy
- Inhalation and Respiratory Drug Delivery
- Nutrition and Health in Aging
- Renal function and acid-base balance
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Emergency and Acute Care Studies
- Respiratory and Cough-Related Research
- Trauma Management and Diagnosis
- Airway Management and Intubation Techniques
- Cardiac Valve Diseases and Treatments
- Ultrasound in Clinical Applications
- Vasculitis and related conditions
- Eosinophilic Disorders and Syndromes
- Cardiac tumors and thrombi
- Respiratory Support and Mechanisms
- Bacterial Infections and Vaccines
- Infective Endocarditis Diagnosis and Management
- Moyamoya disease diagnosis and treatment
- Pharmacovigilance and Adverse Drug Reactions
Universidade do Porto
2014-2024
Hospital de São João
2015-2024
Hospital Beatriz Ângelo
2024
Centro Hospitalar de Trás os Montes e Alto Douro
2024
University of Trás-os-Montes and Alto Douro
2024
PT Inovação e Sistemas (Portugal)
2023
University of Cape Verde
2019
University Hospital of Lausanne
2017
University Health Network
2017
Universitat Autònoma de Barcelona
2017
Abstract Background To characterize and identify prognostic factors for 28-day mortality among patients with hospital-acquired fungemia (HAF) in the Intensive Care Unit (ICU). Methods A sub-analysis of a prospective, multicenter non-representative cohort study conducted 162 ICUs 24 countries. Results Of 1156 bloodstream infections (HA-BSI) included EUROBACT study, 96 had HAF. Median time to its diagnosis was 20 days (IQR 10.5–30.5) 9 3–15.5) after hospital ICU admission, respectively....
Malaria in Cape Verde is unstable, with a sporadic and seasonal transmission of low endemicity. In this sense, the community perceptions regarding malaria transmission, their attitudes practices against disease are very important to understand better develop best strategical policies achieve elimination goal. This study aim assess knowledge, (KAP) Verdean population about malaria, country step disease.A cross-sectional KAP Survey was performed at household level. A structured open...
Abstract Background Nebulisation of antibiotics is a promising treatment for ventilator-associated pneumonia (VAP) caused by multidrug-resistant organisms. Ensuring effective antibiotic concentrations at the site infection in interstitial space fluid crucial clinical outcomes. Current assessment methods, such as epithelial lining and tissue homogenates, have limitations providing longitudinal pharmacokinetic data. Main body Lung microdialysis, an invasive research technique predominantly...
<h3>BACKGROUND:</h3> Intratracheal antibiotic administration is increasingly used for treating respiratory infections. Limited information available on delivery devices, techniques, and safety. <h3>METHODS:</h3> An online survey intratracheal of anti-infective agents in mechanically ventilated adults was answered by health-care workers from 192 ICUs to assess the most commonly current practices, safety issues. We investigated whether ICU usage experience (≥3 y) impacted its performance....
Critically ill patients are typically polymedicated and therefore at a high risk for potential drug interactions. Clinical consequences of drugs interactions vary in severity from mild to lethal events. Since infection is an important issue the Intensive Care Unit (ICU), significant number will receive antimicrobial some stage during their ICU admission. Therefore adequate knowledge about possible between antimicrobials other necessary, since it may not only impact on effectiveness but also...
Mid-regional proadrenomedullin (MR-proADM) is a novel biomarker with potential prognostic utility in patients community-acquired pneumonia (CAP).To evaluate the value of MR-proADM levels at ICU admission for further severity stratification and outcome prediction, its kinetics as an early predictor response severe CAP (SCAP).Prospective, single-center, cohort study 19 SCAP admitted to within 12h after first antibiotic dose.At median was 3.58nmol/l (IQR: 2.83-10.00). No significant association...
A sample of 153 children was drawn from a teaching hospital in Säo Paulo, Brazil. It comprised 51 pneumonia cases and equal number non-respiratory healthy controls matched by age sex. Age ranged 1 month to 7 years. They were all submitted standard protocol investigate clinical symptoms signs, diagnosis supported X-ray images. Univariate data analysis contrasting non-pneumonia subjects suggested that the best indicators would be chest auscultation, history breathlessness, cough, in-drawing...
Churg-Strauss syndrome (CSS) is an unusual disease that presents as systemic vasculitis and peripheral eosinophilia in patients with atopic constitution. Cardiac involvement often not prominent on initial presentation, but important cause of morbidity mortality CSS. We report the case a young woman severe acute myocarditis. Coronary arteriography demonstrated extensive focal vasculopathy, consistent coronary vasculitis, myocardial biopsy showed eosinophilic This presentation led to diagnosis...