Thiago Lisboa
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Antibiotic Use and Resistance
- Emergency and Acute Care Studies
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Antibiotic Resistance in Bacteria
- Influenza Virus Research Studies
- Healthcare Decision-Making and Restraints
- Respiratory viral infections research
- Healthcare Regulation
- Cardiac Arrest and Resuscitation
- Disaster Response and Management
- Airway Management and Intubation Techniques
- Antibiotics Pharmacokinetics and Efficacy
- Thermal Regulation in Medicine
- Neutropenia and Cancer Infections
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Infection Control in Healthcare
Hospital de Clínicas de Porto Alegre
2016-2025
Santa Casa Hospital
2015-2025
Universidade Federal do Rio Grande do Sul
2014-2024
Brazilian Research in Intensive Care Network
2020-2024
Royal College of Music
2024
Imperial College London
2024
Universidade La Salle
2020-2023
Hospital do Coração
2016-2022
Hospital São Paulo
2006-2021
Evidence (Italy)
2021
Objective: To provide an update to “Surviving Sepsis Campaign Guidelines for Management of and Septic Shock: 2012.” Design: A consensus committee 55 international experts representing 25 organizations was convened. Nominal groups were assembled at key meetings (for those members attending the conference). formal conflict-of-interest (COI) policy developed onset process enforced throughout. stand-alone meeting held all panel in December 2015. Teleconferences electronic-based discussion among...
Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) is associated with substantial mortality and use of health care resources. Dexamethasone might attenuate lung injury in these patients.
Hydroxychloroquine and azithromycin have been used to treat patients with coronavirus disease 2019 (Covid-19). However, evidence on the safety efficacy of these therapies is limited.We conducted a multicenter, randomized, open-label, three-group, controlled trial involving hospitalized suspected or confirmed Covid-19 who were receiving either no supplemental oxygen maximum 4 liters per minute oxygen. Patients randomly assigned in 1:1:1 ratio receive standard care, care plus...
Abstract Updates This is the fourteenth version (thirteenth update) of living guideline, replacing earlier versions (available as data supplements). New recommendations will be published updates to this guideline. Clinical question What role drugs in treatment patients with covid-19? Context The evidence base for therapeutics covid-19 evolving numerous randomised controlled trials (RCTs) recently completed and underway. Emerging SARS-CoV-2 variants subvariants are changing therapeutics. new?...
Abstract Objective To determine whether tocilizumab improves clinical outcomes for patients with severe or critical coronavirus disease 2019 (covid-19). Design Randomised, open label trial. Setting Nine hospitals in Brazil, 8 May to 17 July 2020. Participants Adults confirmed covid-19 who were receiving supplemental oxygen mechanical ventilation and had abnormal levels of at least two serum biomarkers (C reactive protein, D dimer, lactate dehydrogenase, ferritin). The data monitoring...
<h3>Importance</h3> Intravenous fluids are used for almost all intensive care unit (ICU) patients. Clinical and laboratory studies have questioned whether specific fluid types result in improved outcomes, including mortality acute kidney injury. <h3>Objective</h3> To determine the effect of a balanced solution vs saline (0.9% sodium chloride) on 90-day survival critically ill <h3>Design, Setting, Participants</h3> Double-blind, factorial, randomized clinical trial conducted at 75 ICUs...
Abstract Clinical question What is the role of drugs in preventing covid-19? Why does this matter? There widespread interest whether drug interventions can be used for prevention covid-19, but there uncertainty about which drugs, if any, are effective. Recommendations The second version living guideline reiterates previous strong recommendation against use hydroxychloroquine and includes a new conditional tixagevimab-cilgavimab individuals who do not have covid-19. How was created This from...
Objectives: Information on clinical practice regarding the diagnosis of pneumonia in European intensive care units is limited. The aim this study was to describe spectrum actual diagnostic practices a large sample units. Design: Prospective, observational, multicenter study. Setting: Twenty-seven nine countries. Patients: Consecutive patients requiring invasive mechanical ventilation for an admission or receiving >48 hrs irrespective diagnosis. Interventions: None. Measurements and Main...
Abstract Introduction This study sought to assess the prognostic value of kinetics procalcitonin (PCT), C-reactive protein (CRP) and clinical scores (clinical pulmonary infection score (CPIS), Sequential Organ Failure Assessment (SOFA)) in outcome ventilator-associated pneumonia (VAP) at an early time point, when adequacy antimicrobial treatment is evaluated. Methods prospective observational cohort was conducted a teaching hospital. The subjects were 75 patients consecutively admitted...
To develop a severity assessment tool to predict mortality in community-acquired pneumonia (CAP) patients intensive care unit (ICU), comparing its performance with Acute Physiology and Chronic Health Evaluation (APACHE) II score American Thoracic Society/Infectious Disease Society of America (ATS/IDSA) criteria as prognostic index CAP requiring ICU admission.Secondary analysis prospective observational cohort study.Thirty-three ICUs.Five hundred twenty-nine adult admission.A was developed...
Sedation overuse is frequent and possibly associated with poor outcomes in the intensive care unit (ICU) patients. However, association of early oversedation clinical has not been thoroughly evaluated. The aim this study was to assess sedation strategies critically ill adult patients under mechanical ventilation (MV). A secondary analysis a multicenter prospective cohort conducted 45 Brazilian ICUs, including requiring ventilatory support first 48 hours ICU admissions, performed. depth...
Background The effects of convalescent plasma (CP) therapy in hospitalised patients with coronavirus disease 2019 (COVID-19) remain uncertain. This study investigates the effect CP on clinical improvement these patients. Methods is an investigator-initiated, randomised, parallel arm, open-label, superiority trial. Patients were randomly (1:1) assigned to two infusions plus standard care (SOC) or SOC alone. primary outcome was proportion 28 days after enrolment. Results A total 160 (80 each...