A5037234368- COVID-19 Clinical Research Studies
- Renin-Angiotensin System Studies
- Birth, Development, and Health
- Chronic Kidney Disease and Diabetes
- Hormonal Regulation and Hypertension
- Long-Term Effects of COVID-19
- Diet and metabolism studies
- Asthma and respiratory diseases
- Inflammatory mediators and NSAID effects
- Acne and Rosacea Treatments and Effects
- Gastroesophageal reflux and treatments
- Dermatology and Skin Diseases
- Pneumonia and Respiratory Infections
- Dialysis and Renal Disease Management
- Infectious Encephalopathies and Encephalitis
- Cardiovascular and exercise physiology
- Blood Pressure and Hypertension Studies
- Drug-Induced Ocular Toxicity
- Musculoskeletal pain and rehabilitation
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Pain Mechanisms and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Pharmacological Receptor Mechanisms and Effects
- Renal Diseases and Glomerulopathies
Celestica (Brasil)
2016-2023
Beneficência Portuguesa de São Paulo
2020
Universidade Estadual de Campinas (UNICAMP)
2006-2007
Hydroxychloroquine and azithromycin have been used to treat patients with coronavirus disease 2019 (Covid-19). However, evidence on the safety efficacy of these therapies is limited.We conducted a multicenter, randomized, open-label, three-group, controlled trial involving hospitalized suspected or confirmed Covid-19 who were receiving either no supplemental oxygen maximum 4 liters per minute oxygen. Patients randomly assigned in 1:1:1 ratio receive standard care, care plus...
Previous Randomised controlled trials (RCT) evaluating chloroquine and hydroxychloroquine in non-hospitalised COVID-19 patients have found no significant difference hospitalisation rates. However, low statistical power precluded definitive answers.We conducted a multicenter, double-blind, RCT 56 Brazilian sites. Adults with suspected or confirmed presenting mild moderate symptoms ≤ 07 days prior to enrollment at least one risk factor for clinical deterioration were randomised (1:1) receive...
This study investigated the safety and efficacy of famciclovir compared to acyclovir in patients with herpes zoster, determine whether two regimens are equally effective for treatment uncomplicated zoster over a period 7days.Patients were randomly assigned receive either 500mg (one tablet) three times daily or 800mg (two capsules) five 7 days. The primary endpoint was defined as time full crusting lesions. Secondary endpoints proportion who achieved complete cure change score signs/symptoms...
Background The Covid-19 pandemic has affected patients with end-stage kidney disease (ESKD). Whether dialysis parameters have a prognostic value in ESKD remains unclear.
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common type of medication used in treatment acute pain. Ketorolac trometamol (KT) is a nonnarcotic, peripherally acting nonsteroidal drug with analgesic effects comparable to certain opioids. Objective: The aim this study was compare efficacy KT and naproxen (NA) low back pain (LBP) moderate-to-severe intensity. Patients methods: In 10-day, Phase III, randomized, double-blind, double-dummy, noninferiority trial,...
<i>Background and Aims:</i> Several lines of clinical evidence support the concept that reduction blood pressure may be useful in prevention diabetic kidney disease. In young spontaneously hypertensive rats (SHR), hypertension reduces several early renal abnormalities including albuminuria. However, contribution nephrin loss to albuminuria this stage experimental diabetes is unknown. Therefore, we investigated whether elevation SHR associated with loss, if hypertension, or...
Purpose: This study investigated the safety and efficacy of fixed-dose combination tablets naproxen/esomeprazole magnesium nimesulide/pantoprazole to determine if both regimens are equally suited relieve pain in patients with osteoarticular diseases dyspeptic symptoms. Methods: Patients were randomly assigned receive either (100 mg/20 mg) twice daily or (500 for 14 days. The primary endpoint was defined as mean change modified Western Ontario McMaster Universities Osteoarthritis Index...