Fábio Holanda Lacerda
A5085150425- Respiratory Support and Mechanisms
- Family and Patient Care in Intensive Care Units
- Religion and Society in Latin America
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Religion and Society Interactions
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Religion, Society, and Development
- Hemodynamic Monitoring and Therapy
- Anesthesia and Sedative Agents
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Palliative and Oncologic Care
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Palliative Care and End-of-Life Issues
- Cardiac, Anesthesia and Surgical Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Renal function and acid-base balance
- Healthcare Decision-Making and Restraints
- Cultural and Social Studies in Latin America
- Neurosurgical Procedures and Complications
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal Respiratory Health Research
- Cardiovascular Disease and Adiposity
Hospital Geral de Fortaleza
2022-2025
Hospital Sírio-Libanês
2025
Hospital da Luz
2019-2020
Hospital de Clínicas de Porto Alegre
2019-2020
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2016-2020
Associação de Medicina Intensiva Brasileira
2020
AC Camargo Hospital
2019
Centro Universitário FEI
2018
Universidade de São Paulo
2017-2018
Intensive Care Society
2017
<h3>Importance</h3> Intravenous fluids are used for almost all intensive care unit (ICU) patients. Clinical and laboratory studies have questioned whether specific fluid types result in improved outcomes, including mortality acute kidney injury. <h3>Objective</h3> To determine the effect of a balanced solution vs saline (0.9% sodium chloride) on 90-day survival critically ill <h3>Design, Setting, Participants</h3> Double-blind, factorial, randomized clinical trial conducted at 75 ICUs...
Rationale: The effects of balanced crystalloid versus saline on clinical outcomes for ICU patients may be modified by the type fluid that received initial resuscitation and admission. Objectives: To assess whether results a randomized controlled trial could affected use before enrollment admission type. Methods: Secondary post hoc analysis BaSICS (Balanced Solution in Intensive Care Study) trial, which compared solution (Plasma-Lyte 148) with 0.9% ICU. Patients were categorized according to...
Slower intravenous fluid infusion rates could reduce the formation of tissue edema and organ dysfunction in critically ill patients; however, there are no data to support different during challenges for important outcomes such as mortality.To determine effect a slower rate vs control on 90-day survival patients intensive care unit (ICU).Unblinded randomized factorial clinical trial 75 ICUs Brazil, involving 11 052 requiring at least 1 challenge with risk factor worse were from May 29, 2017,...
Limited data is available to evaluate the burden of device associated healthcare infections (HAI) [central line bloodstream infection (CLABSI), catheter urinary tract (CAUTI), and ventilator pneumonia (VAP)] in low and-middle-income countries. Our aim investigate population attributable mortality fraction absolute difference HAI a broad critically ill patients from Brazil. Multicenter cohort study September 2019 December 2023 with prospective individual patient collection. VAP, CLABSI, CAUTI...
Objective: To compare the impact of single-bed versus multibed room intensive care units (ICU) architectural designs on stress and burnout ICU staff satisfaction family visitors. Background: There are countless variations among ICUs, but all involve or rooms. Although it is well known that design affects important patient outcomes, effect has been insufficiently studied. Methods: Among visitors, was evaluated with Lipp’s Inventory Stress Symptoms. Maslach Burnout Inventory. Family visitor...
To evaluate the impact of an opioid-sparing pain management protocol on overall opioid consumption and clinical outcomes.This was a single-center, quasi-experimental, retrospective, before after cohort study. We used interrupted time series to analyze changes in levels trends utilization different analgesics. bivariate comparisons cohorts as well logistic regression quantile for adjusted estimates.We included 988 patients preintervention period 1,838 postintervention period. Fentanyl...
Qual é o desempenho dos candidatos evangélicos nas eleições para legislativo no Brasil? Seriam as candidaturas pentecostais responsáveis pela representação política evangélicos? Teriam igrejas um alto grau de sucesso eleitoral? A influência na brasileira vem ganhando crescente destaque mídia e academia. Ela consequência da rápida expansão do pentecostalismo Brasil. literatura prévia assumiu que controlariam seus fiéis como “rebanho eleitoral”. partir uma discussão conceitual sobre candidato...
Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies acute respiratory distress syndrome. Whether a driving pressure-limiting strategy can improve clinical outcomes is unclear.
Since the 1980s, number of Pentecostal candidates elected to Brazilian legislatures has grown remarkably. Literature argued that phenomenon is related churches’ support for particular candidates. To date, however, this claim been based only on ethnographies or studies relying a few cases Drawing from new data set Evangelical (Protestant) Federal Chamber Deputies and state legislative assemblies, I try answer following questions: Do raise fewer campaign resources than other candidates? What...
To describe the characteristics and outcomes of patients undergoing mechanical ventilation withdrawal to compare them mechanically ventilated with limitations (withhold or withdrawal) life-sustaining therapies but who did not undergo withdrawal.This was a retrospective cohort study from January 2014 December 2018 any organ support limitation admitted single intensive care unit. We compared underwent those regarding unit hospital mortality length stay in both an unadjusted analysis propensity...
Abstract Background Nosocomial sepsis is a major healthcare issue, but there are few data on estimates of its attributable mortality. We aimed to estimate mortality fraction (AF) due nosocomial sepsis. Methods Matched 1:1 case–control study in 37 hospitals Brazil. Hospitalized patients participating were included. Cases hospital non-survivors and controls survivors, which matched by admission type date discharge. Exposure was defined as occurrence sepsis, antibiotic prescription plus...
To report the statistical analysis plan (first version) for Balanced Solutions versus Saline in Intensive Care Study (BaSICS).BaSICS is a multicenter factorial randomized controlled trial that will assess effects of Plasma-Lyte 148 0.9% saline as fluid choice critically ill patients, well slow (333mL/h) rapid (999mL/h) infusion speed during challenges, on important patient outcomes. The type be blinded investigators, patients and analyses. No blinding possible but all analyses kept...
Rationale: Coated devices may reduce biofilm formation and the occurrence of device-related infections in critically ill patients. A bundle coated (an endotracheal tube [ETT], central venous catheter [CVC], urinary [UC]) simultaneously inserted optimize benefits patients with most severe illness.Objectives: To assess feasibility a randomized controlled trial on simultaneous insertion gold/silver/palladium-coated versus uncoated severely patients, which required sequential all three ETT, CVC,...
To describe the use of neuromuscular blockade as well other practices among Brazilian physicians in adult intensive care units.An online national survey was designed and administered to intensivists. Questions were selected using Delphi method assessed physicians' demographic data, unit characteristics, regarding airway management, sedation during endotracheal intubation unit. As a secondary outcome, we applied multivariate analysis evaluate factors associated with blockade.Five hundred...
Shorter courses of antimicrobial therapy have been shown to be non-inferior longer durations for the management several infections. However, data on critically ill patients with severe infections by multidrug-resistant Gram-negative bacteria (MDR-GNB) are scarce. In duratiOn theraPy in infecTIons MultIdrug-reSistant gram-nEgative (OPTIMISE) trial, we assessed non-inferiority 7-day versus 14-day intensive care unit (ICU)-acquired MDR-GNB. This was a randomised multicenter, open-label,...
Este artigo não possui um resumo.
RESUMO Contexto: Em estudos observacionais sobre a síndrome do desconforto respiratório agudo, sugeriu-se que driving pressure é o principal fator de lesão pulmonar induzida por ventilador e mortalidade. Não está claro se uma estratégia limitação da pode melhorar os desfechos clínicos. Objetivo: Descrever protocolo plano análise estatística serão usados para testar envolvendo titulação pressão positiva expiratória final acordo com melhor complacência respiratória redução volume corrente...
Ao contrário do que previam os teóricos secularismo, a esfera pública tem, ao longo último século, estreitado laços com religiosa. Na América Latina, atores e discursos religiosos, seja finalidade de mobilizar o eleitorado, para defesa interesses grupos têm se tornado constantes na arena política. Tema muito discutido principalmente mídia, ainda são poucos trabalhos sobre complexa relação entre religião Este dossiê tem por objetivo contribuir temática reunir estudos explorem política em...
religiosas e antirreligiosas) de forma justa democrática 3 .