A5006066036- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Palliative Care and End-of-Life Issues
- Emergency and Acute Care Studies
- Family and Patient Care in Intensive Care Units
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Intensive Care Unit Cognitive Disorders
- Patient Safety and Medication Errors
- Cardiac Arrest and Resuscitation
- Disaster Response and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Ultrasound in Clinical Applications
- Leptospirosis research and findings
- Advanced X-ray and CT Imaging
- Long-Term Effects of COVID-19
- Acute Kidney Injury Research
- Central Venous Catheters and Hemodialysis
- Healthcare Regulation
- Radiation Dose and Imaging
- Viral Infections and Vectors
- Geriatric Care and Nursing Homes
- Frailty in Older Adults
- Pneumothorax, Barotrauma, Emphysema
Hospital São Rafael
2016-2025
Universidade Federal da Bahia
2024-2025
University of Michigan
2025
Michigan United
2025
D’Or Institute for Research and Education
2019-2024
Weatherford College
2020
Hospital Samaritano de São Paulo
2020
Universidade de São Paulo
2009-2019
Sport Lisboa e Benfica
2019
San Antonio College
2019
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promotes challenging immune and inflammatory phenomena. Though various therapeutic possibilities have been tested against disease 2019 (COVID-19), the most adequate treatment has not yet established. Propolis is a natural product with considerable evidence of immunoregulatory anti-inflammatory activities, experimental data point to potential viral targets. We hypothesized that propolis can reduce negative effects COVID-19.In...
ABSTRACT There is an urgent need for improved diagnosis of leptospirosis, emerging infectious disease which imparts a large burden in developing countries. We evaluated the use Leptospira immunoglobulin (Ig)-like (Lig) proteins as serodiagnostic marker leptospirosis. Lig have bacterial immunoglobulin-like (Big) tandem repeat domains, moiety found virulence factors other pathogens. Sera from patients identified during urban outbreaks Brazil reacted strongly with immunoblots recombinant...
This study aimed to identify predictors of early (7-day) mortality in patients with septic acute kidney injury (AKI) who required continuous renal replacement therapy (CRRT). Prospective cohort 186 AKI undergoing CRRT at a tertiary hospital, from October 2005 November 2010. After multivariate adjustment, five variables were associated mortality: norepinephrine utilization, liver failure, medical condition, lactate level, and pre-dialysis creatinine level. These combined score, which...
Intensive care unit (ICU) admission triage is performed routinely and often based solely on clinical judgment, which could mask biases. A computerized algorithm to aid ICU decisions was developed classify patients into the Society of Critical Care Medicine's prioritization system. In this study, we sought evaluate reliability validity algorithm.Nine senior physicians evaluated forty vignettes real patients. The reference standard defined as priorities ascribed by two investigators with full...
This study aims to introduce a new index that could become framework for future modification and improvement, retrospectively test the predictability of this collectively individually final bone changes by using existing research data pertinent guided regeneration (GBR). Methods The MAPS score was introduced evaluate bioMechanical, Aesthetic/Anatomical, Pathophysiologic, Subject-related parameters healing assessment 20 patients who underwent GBR in posterior mandible retrospectively....
The aim of the study was to assess clinical utility lactate measured at different time points predict mortality 48 hours and 28 days in septic patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT). Consecutive critically ill AKI CRRT were prospectively studied. Variables collected initiation 24 later. In total, 186 analyzed. Overall 28% 69%. Initial lactate, proportion a clearance superior 10% between survivors [2.0 mmol/L, 1.95 mmol/L 18/45 (40%)]...
Spinnato, J.A. II; Freire, S.; Pinto e Silva, J.L.; Cunha Rudge, M.V.; Martins-Costa, Koch, M.A.; Goco, N.; Santos, B. Cde; Cecatti, J.G.; Costa, R.; Ramos, Moss, Sibai, B.M. Author Information
Abstract Background Intradialytic hypotension, a complication of intermittent hemodialysis, decreases the efficacy dialysis and increases long-term mortality. This study was aimed to determine whether different predialysis ultrasound cardiopulmonary profiles could predict intradialytic hypotension. Methods prospective observational single-center performed in 248 critically ill patients with acute kidney injury undergoing hemodialysis. Immediately before vena cava collapsibility measured by...
To evaluate the factors potentially associated with decision of admission to intensive care unit in Brazil.An electronic survey Brazilian physicians working units. Fourteen variables that were rated as important (from 1 5) by respondents and later grouped "patient-related," "scarcity-related" "administrative-related" factors. The workplace physician characteristics evaluated for correlation factor ratings.During study period, 125 completed survey. scores on patient-related higher their...
To assess the effect of implementation a palliative care program on do-not-resuscitate orders and intensive unit utilization during terminal hospitalizations.
Osteoporosis has become a serious global public health issue. Hence, osteoporotic fracture healing been investigated in several previous studies because there is still controversy over the effect osteoporosis on process. The current study aimed to analyze two different periods of bone normal and osteopenic rats. Sixty, 7-week-old female Wistar rats were randomly divided into four groups: unrestricted immobilized for 2 weeks after osteotomy (OU2), suspended (OS2), 6 (OU6), (OS6). Osteotomy...
Renal replacement therapy is recommended to be initiated immediately in patients with life-threatening acute kidney injury (AKI)−related symptoms. Ultrasound-guided insertion of hemodialysis catheter for vascular access.1Frykholm P. Pikwer A. Hammarskjöld F. et al.Clinical guidelines on central venous catheterisation.Acta Anaesthesiol Scand. 2014; 58: 508-524Crossref PubMed Scopus (132) Google Scholar, 2Lamperti M. Bodenham A.R. Pittiruti al.International evidence-based recommendations...
Background:In patients with end-stage renal disease, the use of cuffed, tunneled dialysis catheters for hemodialysis has become integral to treatment plans. Fluoroscopy is a widely accepted method insertion and positioning cuffed catheters, because it easy use, accurate reliable, relatively low incidence complications. The purpose our study was evaluate feasibility catheter placement without fluoroscopy but dynamic ultrasound-imaging-based guided technique. Methods:From January 2015 December...
ABSTRACT Background: Circulatory shock is a life-threatening disorder that associated with high mortality, state of systemic and tissue hypoperfusion can lead to organ failure, including the brain, where altered mental often observed. We hypothesized cerebral autoregulation (CA) impaired in patients circulatory shock. Methods: Adult healthy controls were included. Cerebral blood flow velocity (CBFV, transcranial Doppler ultrasound) arterial pressure (BP, Finometer or intra-arterial line)...
The aim of this study was to evaluate the occupational radiation dose in interventional cardiology by using a shielding drape on patient. A random with and without protective material conducted. following control parameters were registered: demographic data, number stents, contrast media volume, fluoroscopy time, cine images, kerma-area product cumulative air kerma. Occupational data obtained electronic active dosemeters. No statistically significant differences analysed registered. median...