Sérgio Pinto de Souza

ORCID: 0000-0003-2483-159X
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About
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Research Areas
  • Animal Virus Infections Studies
  • Sepsis Diagnosis and Treatment
  • Bee Products Chemical Analysis
  • Obstructive Sleep Apnea Research
  • Viral gastroenteritis research and epidemiology
  • Health and Lifestyle Studies
  • Virus-based gene therapy research
  • SARS-CoV-2 and COVID-19 Research
  • Acute Kidney Injury Research
  • Essential Oils and Antimicrobial Activity
  • Insect and Pesticide Research
  • Sleep and related disorders
  • Education Pedagogy and Practices
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Complementary and Alternative Medicine Studies
  • Systemic Lupus Erythematosus Research
  • Hepatitis C virus research
  • Electrolyte and hormonal disorders
  • COVID-19 Clinical Research Studies
  • Renal function and acid-base balance
  • Hepatitis B Virus Studies
  • Viral Infections and Immunology Research
  • Ion Transport and Channel Regulation
  • Hemodynamic Monitoring and Therapy
  • Education and Digital Technologies

Universidade de São Paulo
1999-2025

D’Or Institute for Research and Education
2021-2024

Hospital São Rafael
2020-2024

Escola Bahiana de Medicina e Saúde Pública
2006-2024

Hospital Universitário da Universidade de São Paulo
2023-2024

Hospital do Coração
2024

Universidade Salvador
2021

Universidade Federal da Bahia
2014

Institute of Rural Management Anand
2013

Hospital de Santo António
2006

Acute kidney injury is a common complication in critically ill patients, and the RIFLE, AKIN KDIGO criteria are used to classify these patients. The present study's aim was compare as predictors of mortality patients.Prospective cohort study using medical records source data. All patients admitted intensive care unit were included. exclusion hospitalization for less than 24 hours death. Patients followed until discharge or Student's t test, chi-squared analysis, multivariate logistic...

10.5935/0103-507x.20130050 article EN Revista Brasileira de Terapia Intensiva 2013-01-01

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promotes challenging immune and inflammatory phenomena. Though various therapeutic possibilities have been tested against disease 2019 (COVID-19), the most adequate treatment has not yet established. Propolis is a natural product with considerable evidence of immunoregulatory anti-inflammatory activities, experimental data point to potential viral targets. We hypothesized that propolis can reduce negative effects COVID-19.In...

10.1016/j.biopha.2021.111526 article EN Biomedicine & Pharmacotherapy 2021-03-20

Insufficient/irregular sleep patterns are common conditions, but their cardiovascular consequences and strategies to minimize these risks poorly explored. We aimed determine whether weekend extension (catch-up sleep) social jetlag may impact the incidence of subclinical atherosclerosis. performed a 7-day wrist actigraphy in this cohort study monitor parameters. Coronary artery calcium (CAC) was measured at two different time points. Catch-up-sleep by calculating minus weekday duration....

10.1093/sleep/zsaf039 article EN SLEEP 2025-02-13

Objective: This study aimed to describe and compare the characteristics clinical outcomes of patients with septic non-septic acute kidney injury.Methods: evaluated an open cohort 117 critically ill injury who were consecutively admitted intensive care unit, excluding a history advanced-stage chronic disease, transplantation, hospitalization or death in period shorter than 24 hours.The presence sepsis in-hospital exposure primary variables this study, respectively.A confounding analysis was...

10.5935/0103-507x.20140059 article EN cc-by-nc Revista Brasileira de Terapia Intensiva 2014-01-01

Multiple lineages of Brazilian strains from 2007 to 2008 avian infectious bronchitis virus (IBV) were detected in flocks breeders, broilers, and layers. Organs samples 20 IBV-positive with variable clinical signs submitted the partial amplification S gene (nucleotides 726-1071) IBV. Fifteen sequenced segregated a unique cluster subdivided three subclusters (Brazil 01, 02, 03). Whereas could be classified as Massachusetts (Mass) genotype, remaining two strains, originating reproductive...

10.1637/9218-121709-reg.1 article EN Avian Diseases 2010-06-01

We used a reverse transcription-polymerase chain reaction (RT-PCR) to obtain the genotypes of circulating hepatitis C virus (HCV) in patients from Gastro-Hepatology Unit city Salvador (Bahia State) northeastern Brazil. Viral RNA was detected 83 (65.4%) 127 anti-HCV seropositive serum samples. Positivity significantly associated with alterations levels aspartate aminotransferase and alanine (P < 0.05). Genotyping HCV performed by RT-PCR using genotype-specific primers core region: 24.1%...

10.4269/ajtmh.2000.62.257 article EN American Journal of Tropical Medicine and Hygiene 2000-02-01

Rotaviruses are the main agents responsible for diarrhea in different animal species and infantile gastroenteritis. These viruses have been isolated from various avian often associated with poult enteritis mortality syndrome. Nevertheless, knowledge of rotavirus infection turkeys is scarce. Six group A strains obtained pooled enteric contents diarrheic were MA-104 cell culture typed as G6P1, a typical bovine genotype. Additionally, electropherotypes showed migration pattern identical to...

10.1637/9765-041911-resnote.1 article EN Avian Diseases 2011-12-01

From the Department of Internal Medicine, Hospital Santo Antonio, Salvador, Brazil. Correspondence: Carlos Geraldo Guerreiro de Moura, Rua Manoel Barreto, no. 404, Ed Europa, Ap. 301, Graça, CEP 40150360, Bahia, E-mail: [email protected].

10.1097/rhu.0b013e3181c7e31c article EN JCR Journal of Clinical Rheumatology 2009-12-26

Among candidate treatment options for COVID-19, propolis, produced by honey bees from bioactive plant exudates, has shown potential against viral targets and demonstrated immunoregulatory properties. We conducted a randomized, controlled, open-label, single center trial, with standardized propolis product (EPP-AF) on hospitalized adult COVID-19 patients. Patients received standard care plus at an oral dose of 400mg/day (n=40) or 800mg/day (n=42) seven days, alone (n=42). Standard included...

10.1101/2021.01.08.20248932 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-01-09

Introduction: Sepsis is a leading precipitant of Acute Kidney Injury (AKI) in intensive care unit (ICU) patients, and associated with high mortality rate. Objective: We aimed to evaluate the risk factors for dialysis cohort AKI patients predominantly septic etiology. Methods: Adult from an ICU whom nephrology consultation was requested were included. End-stage chronic renal failure kidney transplant excluded. Results: 114 followed. Most had sepsis (84%), AKIN stage 3 (69%) oliguria (62%) at...

10.5935/0101-2800.20140067 article EN cc-by Brazilian Journal of Nephrology 2014-01-01

Patients on haemodialysis (HD) present a significant inflammatory status, which has pronounced negative impact their outcomes. Propolis is natural resin with anti-inflammatory and immunomodulatory properties. We assessed the safety of standardized Brazilian green propolis extract (EPP-AF®) status in patients under conventional HD. were assigned to receive 200 mg/day EPP-AF® for 4 weeks followed by without drug, changes plasma levels interleukins (ILs), interferon gamma (IFN-γ), tumour...

10.1155/2022/1035475 article EN cc-by International Journal of Nephrology 2022-11-22

Abstract SARS-CoV-2 and its different variants caused a “wave wave” pandemic pattern. During the first wave we demonstrated that standardized Brazilian green propolis extract (EPP-AF®) reduces length of hospital stay in adult patients with COVID-19. Afterwards, decided to evaluate impact EPP-AF hospitalized during third pandemic. BeeCovid2 was randomized, double-blind, placebo-controlled clinical trial COVID-19 patients. Patients were allocated receive an oral dose 900 mg/day EPP-AF® or...

10.1038/s41598-023-43764-w article EN cc-by Scientific Reports 2023-10-27

This 66-year-old man presented with fatigue, paresthesia of the legs, weight loss, and shoulder enlargement, limitation movement. Periorbital ecchymoses (the “raccoon” sign) were present. What's diagnosis?

10.1056/enejmicm040061 article EN New England Journal of Medicine 2004-12-15

Coronavirus disease 2019 (COVID-19) is an emerging infectious caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which began as outbreak in Wuhan, China and has spread rapidly across the globe. Although most infections are mild, patients with critical COVID-19 face deterioration of function may also have extrapulmonary manifestations, mostly affecting kidney, digestive tract, heart, nervous system. Here, we prospectively evaluated presence SARS-CoV-2 genetic material...

10.1177/03000605211015555 article EN cc-by-nc Journal of International Medical Research 2021-05-01

ACIDITY OF HUMIC ACIDS.The acidity determinations method of humic acids (HA) content was developed by Schnitzer and Gupta is a very well known procedure.Nevertheless, care necessary to prevent measure errors due non-controlled BaCO 3 production, during the filtration titration HA total acidity.To overcome this problem, we in our laboratory simple system for determination under inert atmosphere.This enables better reproducibility accuracy total, carboxylic phenolic measures than those method.

10.1590/s0100-40421999000600018 article EN cc-by-nc Química Nova 1999-12-01

In Brief Acute calcific periarthritis of the fingers can be confused with infection or other crystal diseases.

10.1097/01.rhu.0000173618.15904.43 article EN JCR Journal of Clinical Rheumatology 2005-08-01

Abstract The novel coronavirus disease (COVID-19) is an emerging infectious caused by SARS-CoV-2, which began as outbreak in Wuhan, China and spread rapidly throughout the globe. Although majority of infections are mild, severe critical COVID-19 patients face deterioration respiratory function, may also present extrapulmonary manifestations, mostly affecting kidney, digestive tract, heart nervous system. Here, we prospectively evaluated presence SARS-CoV-2 genetic material RT-PCR urine...

10.1101/2021.01.13.21249576 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-01-15

Abstract Background The 2019 coronavirus disease (COVID-19) pandemic continues to spread and affects large numbers of people with unprecedented impacts. Experimental evidence has already been obtained for use the standardized extract Brazilian green propolis (EPP-AF) against viral targets, clinical rationality demonstrated testing this as an adjunct treatment in patients affected by COVID-19. BeeCovid2 study aims assess whether EPP-AF impact on improvement hospitalized COVID-19 reducing...

10.1186/s13063-022-06176-1 article EN cc-by Trials 2022-04-04
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