A5033155073- Bee Products Chemical Analysis
- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Insect and Pesticide Research
- Complementary and Alternative Medicine Studies
- Medical and Biological Ozone Research
- Pomegranate: compositions and health benefits
- Advancements in Transdermal Drug Delivery
- Curcumin's Biomedical Applications
- Microencapsulation and Drying Processes
- Wound Healing and Treatments
- Phytochemicals and Antioxidant Activities
- Plant Toxicity and Pharmacological Properties
- Nanoparticles: synthesis and applications
- Tea Polyphenols and Effects
- Insect Pest Control Strategies
- Healthcare and Venom Research
- Pineapple and bromelain studies
- Pesticide Exposure and Toxicity
- Ginkgo biloba and Cashew Applications
- Microbial Metabolism and Applications
- Natural Antidiabetic Agents Studies
- Kidney Stones and Urolithiasis Treatments
- Therapeutic Uses of Natural Elements
- Oral microbiology and periodontitis research
Apis Flora (Brazil)
2015-2024
Universidade Estadual Paulista (Unesp)
2021
Universidade de São Paulo
2008-2019
Universidade de Ribeirão Preto
2014-2016
Instituto de Ciências Farmacêuticas
2011
The immunomodulatory and anti-inflammatory activities of green propolis extracts from Apis mellifera were investigated using acute chronic inflammation models. Swiss mice anesthetized a cotton pellet granuloma was implanted in subcutaneous tissue. Then the divided into six groups received apyrogenic water or different by oral route (5 mg/kg). According to treatment designated as E1A, E1B, E10, E11, E12. control group water. performed days when killed. blood bronchoalveolar lavage (BAL)...
Among remarkable discoveries concerning propolis, such as antifungal, antiviral, and antioxidant activities, its anti-inflammatory, mainly antibacterial, properties deserve special attention when skin wound healing is concerned. Based on this knowing the distinctive performance of bacterial (BC) membranes healing, in work it proposed to demonstrate potent antimicrobial activity a novel propolis containing biocellulose membrane. The obtained propolis/BC membrane was able adsorb not only...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promotes challenging immune and inflammatory phenomena. Though various therapeutic possibilities have been tested against disease 2019 (COVID-19), the most adequate treatment has not yet established. Propolis is a natural product with considerable evidence of immunoregulatory anti-inflammatory activities, experimental data point to potential viral targets. We hypothesized that propolis can reduce negative effects COVID-19.In...
Baccharis dracunculifolia DC (Asteraceae) is the main botanical source used by honeybees to produce Brazilian green propolis whose hepatoprotective properties have been already described. In this work we investigated protective effects of glycolic extract B. (GEBd) against oxidative stress in isolated rat liver mitochondria (RLM). The GEBd was prepared fractionated percolation using propylene glycol as solvent. total phenols and flavonoids, which are substances with recognized antioxidant...
The aim of this study was to develop a formulation, containing the propolis standardized extract (EPP-AF(®)), which can assist in healing skin lesions. To achieve objective antimicrobial activity and chemical composition determined. final product subjected vitro vivo pre-clinical evaluation. broth macrodilution method used determine extracts formulations against microorganisms most commonly found burns, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus...
Propolis extracts have gained the attention of consumers and researchers due to their unique chemical compositions functional properties such as its anti-inflammatory activity. Recently, it was described a complex that is also important in inflammatory processes, named inflammasome. The inflammasomes are large molecular platform formed cell cytosol response stress signals, toxins, microbial infections. Once activated, inflammasome induces caspase-1, which turn processing cytokines IL-1 β...
ABSTRACT Propolis, a natural product of plant resins, is used by the bees to seal holes in their honeycombs and protect hive entrance. However, propolis has also been folk medicine for centuries. Here, we apply power Saccharomyces cerevisiae as model organism studies genetics, cell biology, genomics determine how affects fungi at cellular level. Propolis able induce an apoptosis death response. increased exposure provides corresponding increase necrosis We showed that cytochrome c but not...
Since the beginning of propolis research, several groups have studied its antibacterial, antifungal, and antiviral properties. However, most these studies only employed ethanolic extract (PEE) leading to little knowledge about biological activities water (PWE). Based on this, in a previous study, we demonstrated anti-inflammatory immunomodulatory PWE. In order better understand equilibrium between effectiveness toxicity, which is essential for new medicine, characteristics PWE were analyzed....
Candida albicans is the most common fungal pathogen of humans, forming both commensal and opportunistic pathogenic interactions, causing a variety skin soft tissue infections in healthy people. In immunocompromised patients C. can result invasive, systemic that are associated with high incidence mortality. Propolis complex mixture several resinous substances which collected from plants by bees. Here, we demonstrated fungicidal activity propolis against all three morphogenetic types...
Propolis is a bee product that results from the mixture of beeswax and resinous compounds. It can scavenge free radicals; therefore, it displays antioxidant activity. Here, we have investigated potential propolis produced by three Brazilian stingless species: Melipona quadrifasciata anthidiodes (Mandaçaia) Tetragona clavipes (Borá), which inhabit southeastern region Brazil (state São Paulo), Scaptotrigona spp. (Tubi), inhabits northeastern Maranhão). The activities different species were...
Abstract Brazilian green and red propolis stand out as commercial products for different medical applications. In this article, we report the antimicrobial activities of hydroalcoholic extracts (EGP) (ERP) propolis, well guttiferone E plus xanthochymol (8) oblongifolin B (9) from against multidrug‐resistant bacteria (MDRB). We undertook minimal inhibitory (MIC) bactericidal (MBC) concentrations, inhibition biofilm formation (MICB 50 ), catalase, coagulase, DNase, lipase, hemolysin assays,...
Sepsis is the leading cause of acute kidney injury (AKI) and lung worldwide. Despite therapeutic advances, sepsis continues to be associated with high mortality. Because Brazilian green propolis (GP) has promising anti-inflammatory, antioxidant, immunomodulatory properties, we hypothesized that it would protect kidneys lungs in rats induced by cecal ligation puncture (CLP). Male Wistar were divided into groups-control (sham-operated); CLP (CLP only); + GP treatment at 6 h thereafter)-all...
Green propolis may represent a promising therapeutic alternative against dental anaerobic pathogens because of its antimicrobial action. This study aimed to evaluate the and antibiofilm actions Brazilian green aqueous extract (BGP-AqExt) bacteria. The minimum inhibitory concentration (MIC) microbicide (MMC) were determined standard strains (ATCC)
With the aim of contributing to development more efficient materials for wound care, new topical formulations based on bacterial nanocellulose (BNC) hydrogels containing propolis were produced. Characterizations confirmed incorporation into BNC matrix, maintaining its structure and properties. Rheological analysis that showed thixotropic behavior appropriate application. Chromatographic profiles sustained release biomarkers at least 20 h. The did not present mutagenicity. For application in...
Vulvovaginal candidiasis is the second cause of vaginal infection in USA. Clinical treatment C. albicans infections routinely performed with polyenes and azole derivatives. However, these drugs are responsible for undesirable side effects toxicity. In addition, echinocandin resistance has been described. Propolis a bee product traditionally used due to its antimicrobial, anti-inflammatory, other properties. Therefore, present work aimed evaluate different propolis presentations order their...
Chamomile is a medicinal plant, which presents several biological effects, especially the anti-inflammatory effect. One of compounds related to this effect apigenin, flavonoid that mostly found in its glycosylated form, apigenin-7-glucoside (APG), natural sources. However, affectivity and safety glycoside have not been well explored for topical application. In context, aim work was develop validate reversed-phase high-performance liquid chromatography (RP-HPLC-DAD) method quantify APG...