A5013198614- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Cardiac Arrest and Resuscitation
- Healthcare Regulation
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- COVID-19 and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Healthcare cost, quality, practices
- Emergency and Acute Care Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Public Health in Brazil
- Cardiovascular Function and Risk Factors
- Esophageal and GI Pathology
- Palliative and Oncologic Care
- Cardiac, Anesthesia and Surgical Outcomes
- Ultrasound and Hyperthermia Applications
- Tracheal and airway disorders
- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
Hospital de Clínicas de Porto Alegre
2015-2025
Universidade Federal do Rio Grande do Sul
2006-2024
Hospital de Clínicas
2017-2022
University of California, San Francisco
2022
San Francisco General Hospital
2022
Hospital Moinhos de Vento
2011-2018
Hospital Mãe de Deus
2013-2017
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2017
University of Milan
2017
Abstract Background The long-term effects of mild COVID-19 infection on Health-related Quality Life (HRQoL) are not yet well understood. study objective was to assess HRQoL and factors associated with its worsening 12 months after SARS-CoV-2 infection. Methods Multicenter prospective cohort in Brazil between January 2022 December 2023. Pasrticipants were ≥ 18 years outpatients for symptomatic confirmed by either RT-PCR or antigen test included. Telephone interviews conducted at 1, 3, 6, 9...
Purpose Early discharge from the intensive care unit (ICU) may constitute a strategy of resource consumption optimization; however, unplanned readmission hospitalized patients to an ICU is associated with worse outcome. We aimed compare effectiveness Stability and Workload Index for Transfer score (SWIFT), Sequential Organ Failure Assessment (SOFA) simplified Therapeutic Intervention Scoring System (TISS-28) in predicting or unexpected death first 48 hours after ICU. Methods conducted...
We aimed to investigate a potential association between B-lines and weaning failure.Fifty-seven subjects eligible for ventilation liberation were enrolled. Patients with tracheostomy excluded. Lung ultrasound assessments of six thoracic zones performed immediately before at the exnd spontaneous breathing trial. B-predominance was defined as any profile anterior bilateral B-pattern. followed up 48 hours after extubation.Thirty-eight individuals successfully extubated; 11 failed trial 8 needed...
<h3>BACKGROUND:</h3> Lung ultrasound is increasingly becoming a diagnostic tool in the critical care setting. B-pattern on lung an artifact composed of multiple B-lines and correlates with interstitial edema. A randomized controlled trial concluded that bedside thoracic could predict postextubation distress through changes aeration during weaning procedure; however, it not screen patients before performance spontaneous breathing (SBT). <h3>METHODS:</h3> We conducted 2-year, prospective,...
Both premature and delayed liberation from mechanical ventilation are associated with increased morbidity mortality, fluid balance could negatively influence extubation outcomes. We sought to determine the impact of in 48 h before a spontaneous breathing trial (SBT) on weaning outcomes mixed ICU population.This was prospective observational study 2 adult medical-surgical ICUs. All enrolled subjects met eligibility criteria for ventilation. SBT failure defined as inability tolerate T-piece...
The administration of a high FIO2 to COPD patients breathing spontaneously may result in hypercapnia, due reversal preexisting regional hypoxic pulmonary vasoconstriction, resulting greater dead space. Arterial blood gas trends have not been reported these patients. In 31-bed medical ICU teaching hospital we prospectively investigated the response 17 CO2-retaining patients, after acute respiratory crisis stabilization with noninvasive ventilation, an 1.0 for 40 min, having noninvasively...
Purpose. The long-term outcomes of patients after discharge from tertiary ICUs as they relate to the public versus private healthcare systems in Brazil have not yet been evaluated. Materials and Methods. A multicenter prospective cohort study was conducted compare all-cause mortality physical functional status (PFS) 24 months ICU between adult treated systems. propensity score- (PS-) matched comparison all causes PFS performed. Results. In total, 928 were discharged including 172 (18.6%) 756...
Os autores relatam o caso de um homem imunocompetente admitido com comprometimento agudo do sistema nervoso, crise hipertensiva e insuficiência renal, vindo a receber diagnóstico meningite endocardite infecciosa por Rhodotorula mucilaginosa. Até onde sabemos, esta é primeira descrição infecção simultânea das meninges endotélio causada em paciente sem imunológico.
The long-term effects of mild COVID-19 on physical, cognitive, and mental health are not yet well understood.The purpose this paper is to describe the protocol for ongoing "Post-COVID Brazil" study 2, which aims evaluate factors associated with health-related quality life cardiovascular non-cardiovascular outcomes one year after a episode symptomatic COVID-19.The 2 prospective multicenter that plans enroll 1047 patients (NCT05197647). Centralized, structured telephone interviews conducted at...
Positive fluid status has been associated with a worse prognosis in intensive care unit (ICU) patients. Given the potential for errors calculation of balance totals and problem accounting indiscernible losses, measurement body weight change is an alternative non-invasive method commonly used estimating status. The objective study to compare measurements changes over time assess their association ICU mortality.This prospective observational was conducted 34-bed multidisciplinary tertiary...
Evidence about long-term sequelae after hospitalization for acute respiratory distress syndrome due to COVID-19 is still scarce.
RESUMO Fundamento: As evidências acerca das sequelas a longo prazo após internação por síndrome do desconforto respiratório agudo COVID-19 ainda são escassas. Objetivo: Avaliar alterações nas funções pulmonar, cardíaca e renal na qualidade de vida secundária à COVID-19. Métodos: Trata-se estudo multicêntrico, caso-controle, incluindo 220 participantes. Os casos serão definidos como pacientes hospitalizados devido No Grupo Controle, selecionados indivíduos sem histórico hospitalização nos...
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While COVID-19 vaccination has been shown to reduce the risk of severe illness, its impact on occurrence persistent symptoms in patients with mild Omicron infection remains uncertain. Our objective was investigate whether reduces COVID-19-related 3 months after infection.
Shorter courses of antimicrobial therapy have been shown to be non-inferior longer durations for the management several infections. However, data on critically ill patients with severe infections by multidrug-resistant Gram-negative bacteria (MDR-GNB) are scarce. In duratiOn theraPy in infecTIons MultIdrug-reSistant gram-nEgative (OPTIMISE) trial, we assessed non-inferiority 7-day versus 14-day intensive care unit (ICU)-acquired MDR-GNB. This was a randomised multicenter, open-label,...
OBJETIVO: Comparar a influência de duas estratégias ventilatórias - ventilação controlada volume (VCV) e pressão (VCP) no desempenho funcional enxertos pulmonares em um modelo canino transplante pulmonar unilateral esquerdo, utilizando-se doadores cujos pulmões foram captados após três horas parada cardiocirculatória temperatura ambiente sob mecânica. MÉTODOS: O estudo incluiu 40 cães mestiços randomizados nos grupos VCV VCP. Dos 20 receptores, 5 não sobreviveram ao transplante, período...
Inspiratory fall in intrathoracic pressure during a spontaneous breathing trial (SBT) may precipitate cardiac dysfunction and acute pulmonary edema. We aimed to determine the relationship between radiological signs of congestion prior an SBT weaning outcomes. This was post hoc analysis prospective cohort study involving patients adult medical-surgical ICU. All enrolled individuals met eligibility criteria for liberation from mechanical ventilation. Tracheostomized subjects were excluded. The...
Resumo Fundamento O impacto em longo prazo da hospitalização por COVID-19 sobre a saúde física, mental e cognitiva dos pacientes requer mais investigação. Objetivos Este artigo visa avaliar os fatores associados com qualidade de vida desfechos cardiovasculares não 12 meses após internação hospitalar COVID-19. Métodos estudo multicêntrico prospectivo pretende incluir 611 internados (NCT05165979). Entrevistas telefônicas centralizadas estão programadas para ocorrer três, seis, nove alta [...]