- Heart Failure Treatment and Management
- Long-Term Effects of COVID-19
- Mechanical Circulatory Support Devices
- Ultrasound in Clinical Applications
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Cardiac pacing and defibrillation studies
- COVID-19 and Mental Health
- Public Health in Brazil
- Acute Myocardial Infarction Research
- Medication Adherence and Compliance
- COVID-19 Clinical Research Studies
- Radiation Dose and Imaging
- Cardiovascular Function and Risk Factors
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Coronary Interventions and Diagnostics
- COVID-19 and healthcare impacts
- Healthcare Regulation
- Cardiac Imaging and Diagnostics
- Ultrasound and Hyperthermia Applications
- Intensive Care Unit Cognitive Disorders
- Cardiac tumors and thrombi
- Renal function and acid-base balance
Hospital Moinhos de Vento
2023-2025
Universidade Federal do Rio Grande do Sul
2024
Fundação Universitária de Cardiologia
2010-2023
Instituto do Cérebro
2013-2017
Istituto di Fisiologia Clinica
2013-2017
Although loop diuretics are widely used to treat heart failure (HF), there is scarce contemporary data guide diuretic adjustments in the outpatient setting.In a prospective, randomized and double-blind protocol, we tested safety tolerability of withdrawing low-dose furosemide stable HF outpatients at 11 clinics Brazil. The trial had two blindly adjudicated co-primary outcomes: (i) symptoms assessment quantified as area under curve (AUC) dyspnoea score on visual-analogue scale evaluated 4...
Abstract Background The long-term effects of mild COVID-19 infection on Health-related Quality Life (HRQoL) are not yet well understood. study objective was to assess HRQoL and factors associated with its worsening 12 months after SARS-CoV-2 infection. Methods Multicenter prospective cohort in Brazil between January 2022 December 2023. Pasrticipants were ≥ 18 years outpatients for symptomatic confirmed by either RT-PCR or antigen test included. Telephone interviews conducted at 1, 3, 6, 9...
To evaluate the prognostic value of peak serum lactate and clearance at several time points in cardiogenic shock treated with temporary mechanical circulatory support (MCS) using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or Impella CP®.Serum were measured before MCS 1 h, 6 12 24 h post-MCS 43 patients four tertiary-care centers Southern Brazil. Prognostic was assessed by univariable multivariable analysis receiver operating characteristic (ROC) curves for 30-day...
OBJECTIVES: Proper assessment of dyspnea is important in patients with heart failure.Our aim was to evaluate the use 5-point Likert scale for assess degree pulmonary congestion and determine prognostic value this predicting adverse events failure outpatients.METHODS: We undertook a prospective study outpatients moderate severe failure.The applied during regular outpatient visits, along clinical assessments.Lung ultrasound $15 B-lines an amino-terminal portion pro-B-type natriuretic peptide...
Abstract Background Refractory cardiogenic shock (CS) is associated with high mortality rates, and the use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a therapeutic option has generated discussions. Therefore, its cost-effectiveness, especially in low- middle-income countries like Brazil, remains uncertain.Objectives: To conduct cost-utility analysis from Brazilian Unified Health System perspective to assess cost-effectiveness VA-ECMO combined standard care compared...
New York Heart Association (NYHA) functional class plays a central role in heart failure (HF) assessment but might be unreliable mild presentations. We compared objective measures of HF evaluation between patients classified as NYHA I and II the Rede Brasileira de Estudos em Insuficiência Cardíaca (ReBIC)-1 Trial. The ReBIC-1 Trial included outpatients with stable reduced ejection fraction. All had simultaneous protocol-defined class, 6 min walk test (6MWT), N-terminal pro-brain natriuretic...
Treatment with mechanical circulatory support (MCS) has been proposed to mitigate mortality in cardiogenic shock (CS). However, there is a lack of data on MCS programs implementation and the effect learning curve its outcomes limited resources countries such as Brazil.Prospective cohort patients CS admitted four tertiary-care centers treated Impella CP or veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Clinical were peri-procedural complications, short-term rate, centers' curve....
The long-term effects of mild COVID-19 on physical, cognitive, and mental health are not yet well understood.The purpose this paper is to describe the protocol for ongoing "Post-COVID Brazil" study 2, which aims evaluate factors associated with health-related quality life cardiovascular non-cardiovascular outcomes one year after a episode symptomatic COVID-19.The 2 prospective multicenter that plans enroll 1047 patients (NCT05197647). Centralized, structured telephone interviews conducted at...
Readmissions after an index heart failure (HF) hospitalization are a major contemporary health care problem.
INTRODUÇÃO: Estudos demonstram que as angioplastias primárias realizadas fora do horário de rotina estão relacionadas a pior prognóstico. É objetivo deste estudo avaliar os desfechos das dentro e serviço hemodinâmica. MÉTODOS: Estudo coorte prospectivo, incluindo 112 pacientes consecutivamente atendidos por infarto agudo miocárdio com supradesnivelamento segmento ST (IAM) entre dezembro 2009 janeiro 2010. Características clínicas angiográficas evolução hospitalar foram registradas em banco...
To evaluate a telemonitoring strategy based on automated text messaging and telephone support after heart failure (HF) hospitalization.
Purpose: Lung ultrasound (LUS) assessment of B-lines (also called lung comets) has been recently proposed as a reliable and easy evaluation pulmonary congestion in heart failure (HF) patients. Our aim was to determine the prognostic value LUS predict adverse events HF outpatient clinic. Methods: Ninety-seven patients admitted clinic due advanced systolic (61% men, mean age 53±13years, 27% post-ischaemic 54% idiopathic cardiomyopathy) were enrolled. independently performed during regular...
Evidence about long-term sequelae after hospitalization for acute respiratory distress syndrome due to COVID-19 is still scarce.
RESUMO Fundamento: As evidências acerca das sequelas a longo prazo após internação por síndrome do desconforto respiratório agudo COVID-19 ainda são escassas. Objetivo: Avaliar alterações nas funções pulmonar, cardíaca e renal na qualidade de vida secundária à COVID-19. Métodos: Trata-se estudo multicêntrico, caso-controle, incluindo 220 participantes. Os casos serão definidos como pacientes hospitalizados devido No Grupo Controle, selecionados indivíduos sem histórico hospitalização nos...
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While COVID-19 vaccination has been shown to reduce the risk of severe illness, its impact on occurrence persistent symptoms in patients with mild Omicron infection remains uncertain. Our objective was investigate whether reduces COVID-19-related 3 months after infection.
Background: Heart failure (HF) is the final pathway of most cardiac diseases. Although prevalence HF has increased, due to ageing population, more comprehensive data have shown a reduction in percentage hospital admissions over last years. Objective: Assess morbidity and mortality patients Brazil, Rio Grande do Sul Porto Alegre. Method: The study retrospective analysis from Brazilian Unified Health System's (Sistema Único de Saúde [SUS]) Department Informatics (DataSUS). We evaluated...
Abstract Background: To evaluate the prognostic value of peak serum lactate and clearance at several time points in cardiogenic shock treated with temporary mechanical circulatory support (MCS) using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or Impella CP ® . Methods: Serum were measured before MCS 1h, 6h, 12h, 24h post-MCS 43 patients four tertiary-care centers Southern Brazil. Prognostic was assessed by univariable multivariable analysis receiver operating characteristic...
Resumo Fundamento O impacto em longo prazo da hospitalização por COVID-19 sobre a saúde física, mental e cognitiva dos pacientes requer mais investigação. Objetivos Este artigo visa avaliar os fatores associados com qualidade de vida desfechos cardiovasculares não 12 meses após internação hospitalar COVID-19. Métodos estudo multicêntrico prospectivo pretende incluir 611 internados (NCT05165979). Entrevistas telefônicas centralizadas estão programadas para ocorrer três, seis, nove alta [...]