- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- COVID-19 Clinical Research Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Long-Term Effects of COVID-19
- COVID-19 diagnosis using AI
- Diabetes Treatment and Management
- Trauma and Emergency Care Studies
- COVID-19 and Mental Health
- Advanced X-ray and CT Imaging
- Cardiac Arrest and Resuscitation
- Neurological diseases and metabolism
- Acute Kidney Injury Research
- Abdominal Trauma and Injuries
- Health, Environment, Cognitive Aging
- Genomics and Rare Diseases
- Radiomics and Machine Learning in Medical Imaging
- Diabetes Management and Research
- Sepsis Diagnosis and Treatment
- Public Health in Brazil
- COVID-19 and healthcare impacts
- Respiratory Support and Mechanisms
- Chronic Kidney Disease and Diabetes
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Ultrasound in Clinical Applications
- Neonatal Health and Biochemistry
Hospital de Clínicas Universidade Federal do Paraná
2024
Universidade Federal do Paraná
2024
Santa Casa Hospital
2022
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors improve outcomes in patients with type diabetes, heart failure, and chronic kidney disease, but their effect on of critically ill organ failure is unknown.
The gold-standard method for establishing a microbiological diagnosis of COVID-19 is reverse-transcriptase polymerase chain reaction (RT-PCR). This study aimed to evaluate the accuracy, sensitivity, specificity, positive predictive value (PPV), and negative (NPV) set clinical-radiological criteria screening in patients with severe acute respiratory failure (SARF) admitted intensive care units (ICUs), using (RT-PCR) as reference standard.
Traumatic brain injury (TBI) has substantial physical, psychological, social and economic impacts, with high rates of morbidity mortality. Considering its incidence, the aim this study was to identify epidemiological clinical characteristics that predict mortality in patients hospitalized for TBI intensive care units (ICUs).A retrospective cohort carried out over 18 years old admitted an ICU a Brazilian trauma referral hospital between January 2012 August 2019. compared other traumas terms...
Dysglycemias have been associated with worse prognosis in critically ill patients COVID-19, but data on the association of dysglycemia COVID-19 comparison other forms severe acute respiratory syndrome are lacking. This study aimed to compare occurrence different glycemic abnormalities and admitted intensive care units versus from causes, evaluate adjusted attributable risk assess influence these dysglycemias mortality.We conducted a retrospective cohort consecutive suspected hospitalized...
Abstract Acute neurological emergencies are highly prevalent in intensive care units (ICUs) and impose a substantial burden on patients. This study aims to describe the epidemiology of patients requiring neurocritical Brazil, their differences based primary acute diagnoses identify predictors mortality unfavourable outcomes, along with disease each condition at unit admission. prospective cohort included admitted 36 ICUs four Brazilian regions who were followed for 30 days or until ICU...
The long-term effects of mild COVID-19 on physical, cognitive, and mental health are not yet well understood.The purpose this paper is to describe the protocol for ongoing "Post-COVID Brazil" study 2, which aims evaluate factors associated with health-related quality life cardiovascular non-cardiovascular outcomes one year after a episode symptomatic COVID-19.The 2 prospective multicenter that plans enroll 1047 patients (NCT05197647). Centralized, structured telephone interviews conducted at...
Resumo Fundamento O impacto em longo prazo da hospitalização por COVID-19 sobre a saúde física, mental e cognitiva dos pacientes requer mais investigação. Objetivos Este artigo visa avaliar os fatores associados com qualidade de vida desfechos cardiovasculares não 12 meses após internação hospitalar COVID-19. Métodos estudo multicêntrico prospectivo pretende incluir 611 internados (NCT05165979). Entrevistas telefônicas centralizadas estão programadas para ocorrer três, seis, nove alta [...]
Critical illness is a major ongoing health care burden worldwide and associated with high mortality rates. Sodium-glucose cotransporter-2 inhibitors have consistently shown benefits in cardiovascular renal outcomes. The effects of sodium-glucose acute not been properly investigated.DEFENDER an investigator-initiated, multicenter, randomized, open-label trial designed to evaluate the efficacy safety dapagliflozin 500 adult participants organ dysfunction who are hospitalized intensive unit....
To evaluate the accuracy of persistent AKI risk index (PARI) in predicting acute kidney injury within 72 hours after admission to intensive care unit, injury, renal replacement therapy, and death 7 days patients hospitalized due respiratory failure.This study was done a cohort diagnoses consecutive adult admitted unit eight hospitals Curitiba, Brazil, between March September 2020 failure secondary suspected COVID-19. The COVID-19 diagnosis confirmed or refuted by RT-PCR for detection...
BACKGROUND: Critical illness is a major ongoing health care burden worldwide and associated with high mortality rates. Sodium-glucose cotransporter-2 inhibitors have consistently shown benefits in cardiovascular renal outcomes. The effects of sodium-glucose acute not been properly investigated. METHODS: DEFENDER an investigator-initiated, multicenter, randomized, open-label trial designed to evaluate the efficacy safety dapagliflozin 500 adult participants organ dysfunction who are...
OBJECTIVE: To evaluate the accuracy of persistent AKI risk index (PARI) in predicting acute kidney injury within 72 hours after admission to intensive care unit, injury, renal replacement therapy, and death 7 days patients hospitalized due respiratory failure. METHODS: This study was done a cohort diagnoses consecutive adult admitted unit eight hospitals Curitiba, Brazil, between March September 2020 failure secondary suspected COVID-19. The COVID-19 diagnosis confirmed or refuted by RT-PCR...
To compare, within a cohort of patients with acute respiratory failure, the phenotypes and without COVID-19 in context pandemic evaluate whether is an independent predictor intensive care unit mortality.
OBJECTIVE: To compare, within a cohort of patients with acute respiratory failure, the phenotypes and without COVID-19 in context pandemic evaluate whether is an independent predictor intensive care unit mortality. METHODS: This historical study evaluated 1001 failure suspected admitted to 8 hospitals. Patients were classified as cases non-COVID-19 according real-time polymerase chain reaction results. Data on clinical demographic characteristics collected admission, well daily laboratory...