- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Organ Donation and Transplantation
- Cardiac, Anesthesia and Surgical Outcomes
- Long-Term Effects of COVID-19
- Palliative and Oncologic Care
- Nosocomial Infections in ICU
- Organ Transplantation Techniques and Outcomes
- COVID-19 Clinical Research Studies
- Tissue Engineering and Regenerative Medicine
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pluripotent Stem Cells Research
- Influenza Virus Research Studies
- Abdominal Surgery and Complications
- Healthcare Regulation
- Global Maternal and Child Health
- Epilepsy research and treatment
- Climate Change and Health Impacts
- Vascular Anomalies and Treatments
- Renal Transplantation Outcomes and Treatments
- Anesthesia and Neurotoxicity Research
- Public Health in Brazil
Pontifícia Universidade Católica do Paraná
2019-2023
Hospital Universitário Cajuru
2009-2023
Hospital São Lucas da PUCRS
2023
Brazilian Research in Intensive Care Network
2023
Centro de Estudos e Pesquisa em Saúde Coletiva
2014
Sedation overuse is frequent and possibly associated with poor outcomes in the intensive care unit (ICU) patients. However, association of early oversedation clinical has not been thoroughly evaluated. The aim this study was to assess sedation strategies critically ill adult patients under mechanical ventilation (MV). A secondary analysis a multicenter prospective cohort conducted 45 Brazilian ICUs, including requiring ventilatory support first 48 hours ICU admissions, performed. depth...
familiar, da manutenção clínica do doador falecido e de contraindicações mal atribuídas.
BackgroundGeoeconomic variations in epidemiology, the practice of ventilation, and outcome invasively ventilated intensive care unit (ICU) patients without acute respiratory distress syndrome (ARDS) remain unexplored. In this analysis we aim to address these gaps using individual patient data four large observational studies.MethodsIn pooled harmonised from ERICC, LUNG SAFE, PRoVENT, PRoVENT-iMiC prospective studies, which were conducted June, 2011, December, 2018, 534 ICUs 54 countries. We...
OBJECTIVE: To define the epidemiological profile and main determinants of morbidity mortality in noncardiac high surgical risk patients Brazil. METHODS: This was a prospective, observational multicenter study. All admitted to intensive care units, i.e., those considered risk, within 1-month period were evaluated monitored daily for maximum 7 days unit determine complications. The 28-day postoperative, hospital rates evaluated. RESULTS: Twenty-nine units participated Surgeries performed...
Abstract Acute neurological emergencies are highly prevalent in intensive care units (ICUs) and impose a substantial burden on patients. This study aims to describe the epidemiology of patients requiring neurocritical Brazil, their differences based primary acute diagnoses identify predictors mortality unfavourable outcomes, along with disease each condition at unit admission. prospective cohort included admitted 36 ICUs four Brazilian regions who were followed for 30 days or until ICU...
This study aimed to analyze outcome, clinical and epidemiological characteristics severity factors in adult patients admitted with a diagnosis of infection by virus A (H1N1) public private intensive care units, Paraná, Brazil.Cohort medical charts older than 12 years 11 units 6 cities the state Parana, Brazil, during period 45 days, swine influenza. The was made real time polymerase chain reaction (RT-PCR) nasopharyngeal secretion, or strong suspicion when other causes had been ruled out...
The treatment of tracheal pathologies remains challenging.Nanotechnology allows adding substances to decellularized human amniotic membrane (DHAM), such as 15-Deoxy-∆12,14ProstaglandinJ2 nanoparticles (15D-PGJ2-NC).This study performed a tracheotomy in rabbits randomized into three groups.The tissue repair process was evaluated when treated with DHAM associated or not 15D-PGJ2-NC.The average the area control group 54.76% smaller than and 41.98% + 15D-PGJ2-NC (p=0.004 for both).The had...
RESUMO Introdução A hipertensão intra-abdominal e a sepse são condições clínicas de grande importância alta prevalência em pacientes criticamente enfermos. O diagnóstico precoce permite um tratamento adequado melhora do prognóstico dos doentes. Objetivo objetivo estudo foi analisar os níveis lactato componentes da gasometria ratos submetidos à intra-abdominal. Método experimento utilizou 40 linhagem Wistar divididos 4 grupos: controle, grupo sepse, + induzida pela ligadura punção ceco gerada...
The profiles of polytraumatized patients in intensive care units were characterized. Serum and salivary markers compared with normality between Classes I II APACHE periods hospitalization; these results correlated. This was a prospective study on saliva charts collection (n = 70). Profile: male, 27 years old, blunt traumas collisions. parameters normality: decrease pH, creatinine at admission to Class I, 48 72 hours both classes; K+ h II; Ca+ classes I. Increase urea II, glucose all times...
Most transplanted organs are obtained from brain-dead donors. Inflammation results in a higher rate of rejection. Objectives: The objective this animal model brain death (BD) was to evaluate the effect progressive institution volume expansion, norepinephrine, and combined hormone therapy on clinical, laboratory, histological aspects. Methods: Twenty rabbits were divided: A (control), B (induction BD + infusion crystalloid), C (BD crystalloid noradrenaline (NA)), D vasopressin levothyroxine...
To compare, within a cohort of patients with acute respiratory failure, the phenotypes and without COVID-19 in context pandemic evaluate whether is an independent predictor intensive care unit mortality.
OBJECTIVE: To compare, within a cohort of patients with acute respiratory failure, the phenotypes and without COVID-19 in context pandemic evaluate whether is an independent predictor intensive care unit mortality. METHODS: This historical study evaluated 1001 failure suspected admitted to 8 hospitals. Patients were classified as cases non-COVID-19 according real-time polymerase chain reaction results. Data on clinical demographic characteristics collected admission, well daily laboratory...
Em dezembro de 2019, o mundo se deparou com a eclosão uma pandemia, impactando diretamente nos hábitos e rotinas da população. Dentre as áreas saúde afetadas, estão os programas doação transplantes órgãos. Este estudo objetivou descrever impactos SARS-CoV-2 nas contraindicações clínicas potenciais doadores no estado do Paraná. Trata-se um descritivo dados período entre abril 2018 março 2022. Neste período, foram analisadas notificações Morte Encefálica foco principal desfecho não por...