Emmanuel Nsutebu

ORCID: 0000-0003-4750-1235
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About
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Research Areas
  • Sepsis Diagnosis and Treatment
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial Identification and Susceptibility Testing
  • Antibiotic Use and Resistance
  • Infective Endocarditis Diagnosis and Management
  • Streptococcal Infections and Treatments
  • Global Maternal and Child Health
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Clinical Reasoning and Diagnostic Skills
  • Patient Satisfaction in Healthcare
  • Health Systems, Economic Evaluations, Quality of Life
  • Salmonella and Campylobacter epidemiology
  • Disaster Response and Management
  • Healthcare Systems and Technology
  • Emergency and Acute Care Studies
  • Neonatal and Maternal Infections
  • COVID-19 Clinical Research Studies
  • HIV/AIDS Research and Interventions
  • Diphtheria, Corynebacterium, and Tetanus
  • Central Venous Catheters and Hemodialysis
  • Intensive Care Unit Cognitive Disorders
  • Antibiotic Resistance in Bacteria
  • Climate Change and Health Impacts
  • Trauma and Emergency Care Studies
  • Antifungal resistance and susceptibility

Sheikh Shakhbout Medical City
2020-2025

Royal Liverpool and Broadgreen University Hospital NHS Trust
2012-2022

Hacettepe University
2022

Dr. Behçet Uz Çocuk Hastalıkları Hastanesi
2022

Hospital for Tropical Diseases
2022

Royal Liverpool University Hospital
2014-2021

University of Liverpool
2014-2021

Office of Infectious Diseases
2020

Liverpool Hospital
2014

Bradford Royal Infirmary
2009

Cases of human monkeypox are rarely seen outside west and central Africa. There few data regarding viral kinetics or the duration shedding no licensed treatments. Two oral drugs, brincidofovir tecovirimat, have been approved for treatment smallpox demonstrated efficacy against in animals. Our aim was to describe longitudinal clinical course a high-income setting, coupled with dynamics, any adverse events related novel antiviral therapies.

10.1016/s1473-3099(22)00228-6 article EN cc-by-nc-nd The Lancet Infectious Diseases 2022-05-24

Abstract Updates This is the fourteenth version (thirteenth update) of living guideline, replacing earlier versions (available as data supplements). New recommendations will be published updates to this guideline. Clinical question What role drugs in treatment patients with covid-19? Context The evidence base for therapeutics covid-19 evolving numerous randomised controlled trials (RCTs) recently completed and underway. Emerging SARS-CoV-2 variants subvariants are changing therapeutics. new?...

10.1136/bmj.m3379 article EN BMJ 2020-09-04

The third international consensus definition for sepsis recommended use of a new prognostic tool, the quick Sequential Organ Failure Assessment (qSOFA), based on its ability to predict inhospital mortality and prolonged intensive care unit (ICU) stay in patients with suspected infection. While several studies have compared accuracy qSOFA Systemic Inflammatory Response Syndrome (SIRS) criteria sepsis, few SIRS widely used National Early Warning Score (NEWS).This was retrospective cohort study...

10.1136/emermed-2017-207120 article EN Emergency Medicine Journal 2018-02-21

Abstract Clinical question What is the role of drugs in preventing covid-19? Why does this matter? There widespread interest whether drug interventions can be used for prevention covid-19, but there uncertainty about which drugs, if any, are effective. Recommendations The second version living guideline reiterates previous strong recommendation against use hydroxychloroquine and includes a new conditional tixagevimab-cilgavimab individuals who do not have covid-19. How was created This from...

10.1136/bmj.n526 article EN BMJ 2021-03-01
Guy Thwaites Matthew Scarborough Alexander J. Szubert Emmanuel Nsutebu Robert Tilley and 95 more Julia Greig Sarah Wyllie Peter Wilson Cressida Auckland Janet Cairns Denise Ward Pankaj Lal Achyut Guleri Neil Jenkins Julian Sutton Martin Wiselka Armando González-Ruiz Clive Graham Paul Chadwick Gavin Barlow N Claire Gordon Bernadette C. Young Sarah Meisner Paul McWhinney Ashley Price David Harvey Deepa Nayar Dakshika Jeyaratnam Tim Planche Jane Minton Fleur Hudson Susan Hopkins John Williams M. Estée Török Martin Llewelyn Jonathan D. Edgeworth Timothy M. Walker Matthew Scarborough Musa Kamfose Ana de Veciana N Claire Gordon Leon Peto Gemma Pill Tiphanie Clarke Laura Watson Bernadette C. Young D. Ll. Griffiths A. N. Vaughn Luke Anson Elian Liu Sanuki Perera Lydia Rylance-Knight Carmen Cantell Ruth Moroney Jonathan D. Edgeworth Guy Thwaites Karen Bisnauthsing Antonio Querol-Rubiera Charlotte Gibbs Amita Patel Carolyn Hemsley Anna L. Goodman Duncan Wyncoll Jason S. Biswas Jennifer M. Fitzpatrick L. Jackson Roberts James Millard N. E. Stone Angela Cape Lisa Hurley Chi Kai Tam Emmanuel Nsutebu Marie-Claire Hoyle Kate Maitland Leona Trainor Helen Reynolds Jennifer Harrison Jim Anson Joseph M. Lewis Jonathan Folb Lynsey Goodwin Nicholas J. Beeching Sarah Dyas Helen Winslow Elizabeth A. Foote Paul C. Roberts Pavithra Natarajan Aleš Chrdle Manuel Fenech Hannah Allsop Robert Tilley Rachel Austin-Hutchison Louise Barrett Karen Brookes Leanne Carwithen Andrew Conbeer Richard Cunningham Charlotte Eglinton Rosie Fok Hannah Gott

BackgroundStaphylococcus aureus bacteraemia is a common cause of severe community-acquired and hospital-acquired infection worldwide. We tested the hypothesis that adjunctive rifampicin would reduce bacteriologically confirmed treatment failure or disease recurrence, death, by enhancing early S killing, sterilising infected foci blood faster, reducing risks dissemination metastatic infection.MethodsIn this multicentre, randomised, double-blind, placebo-controlled trial, adults (≥18 years)...

10.1016/s0140-6736(17)32456-x article EN cc-by The Lancet 2017-12-14

Home-based care coverage in Africa is currently very low and likely to reduce drastically the near future. This paper investigates of home-based programmes uses two projects Zambia as case studies. The limited involvement governments provision services appears be one main reasons behind Africa. Governments therefore should provide some form basic and/or strengthen support other institutions providing care. In order facilitate governments' activities, an analysis tasks performed by community...

10.1093/heapol/16.3.240 article EN Health Policy and Planning 2001-09-01

10.1007/s10096-023-04561-5 article EN European Journal of Clinical Microbiology & Infectious Diseases 2023-02-15

Background In 2021, Sheikh Shakhbout Medical City (SSMC) faced an increase in hospital-onset multidrug-resistant organisms; Candida auris increased to 1.4 per 1000 patient days, within critical care areas. This rise prompted the infection prevention and control team enhance cleaning disinfection practices, aiming reduce transmission risks. The focus was on adherence a structured protocol, which included high standards of equipment disinfection, regular audits establishment roles...

10.1136/bmjoq-2024-002958 article EN cc-by-nc-nd BMJ Open Quality 2025-04-01

To analyse the adherence and impact of quality-of-care indicators (QCIs) in management Staphylococcus aureus bloodstream infection a prospective multicentre cohort.Analysis prospective, international S. Aureus Collaboration cohort cases observed between January 2013 April 2015. Multivariable analysis was performed to evaluate QCIs on 90-day mortality.A total 1784 were included. Overall, mortality 29.9% mean follow-up period 118 days. Adherence 67% (n = 1180/1762) for blood cultures, 31%...

10.1016/j.cmi.2022.10.019 article EN cc-by-nc-nd Clinical Microbiology and Infection 2022-10-23

Summary Typhoid fever is difficult to differentiate from other causes of infection such as malaria because their signs and symptoms often overlap. There has been an unprecedented increase in the number typhoid cases diagnosed Cameroon. Febrile patients are treated for simultaneously. This cross‐sectional study was carried out determine prevalence 200 consecutive with clinically compatible verify recent estimates a high Patients were enrolled three 10 provinces Blood culture, thick thin blood...

10.1046/j.1365-3156.2003.01012.x article EN Tropical Medicine & International Health 2003-06-01

ObjectivesTo describe current practice in testing for transmitted antiretroviral drug resistance (TDR) and the prevalence of TDR a large UK HIV-1 cohort.

10.1093/jac/dkn228 article EN Journal of Antimicrobial Chemotherapy 2008-06-10

Staphylococcus aureus bacteraemia is a common and serious infection, with an associated mortality of ~25%. Once in the blood, S. can disseminate to infect almost any organ, but bones, joints heart valves are most frequently affected. Despite infection’s severity, evidence guiding optimal antibiotic therapy weak: fewer than 1,500 patients have been included 16 randomised controlled trials investigating treatment. It uncertain which antibiotics effective, their route administration duration,...

10.1186/1745-6215-13-241 article EN cc-by Trials 2012-12-01

Introduction: Sepsis is a leading cause of morbidity and mortality worldwide particularly in Africa where awareness low resources are limited. There limited reports on the epidemiology, management outcomes sepsis syndromes from Africa. However, this region likely to account for significant proportion global burden which goes unrecognized. It imperative address through research, increased awareness, capacity building introduction practical clinical guidelines. Infections responsible an...

10.11604/pamj.2015.21.323.6462 article EN cc-by Pan African Medical Journal 2015-01-01
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