A5113166496- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Disaster Response and Management
- Hemodynamic Monitoring and Therapy
- Neonatal and Maternal Infections
- Cardiac Arrest and Resuscitation
- Clinical Reasoning and Diagnostic Skills
- Liver Disease and Transplantation
- Traumatic Brain Injury and Neurovascular Disturbances
- Heme Oxygenase-1 and Carbon Monoxide
- Renal function and acid-base balance
- Family and Patient Care in Intensive Care Units
- Climate Change and Health Impacts
- Streptococcal Infections and Treatments
- Emergency and Acute Care Studies
- Drug-Induced Adverse Reactions
- Cardiac, Anesthesia and Surgical Outcomes
- Antibiotic Use and Resistance
- Global Maternal and Child Health
- Pharmacovigilance and Adverse Drug Reactions
- Central Venous Catheters and Hemodialysis
- Machine Learning in Healthcare
- Infective Endocarditis Diagnosis and Management
The UK Sepsis Trust
2012-2025
University Hospitals Birmingham NHS Foundation Trust
2019-2025
Heart of England NHS Foundation Trust
2010-2023
Johns Hopkins University
2018
Kimal (United Kingdom)
2016
Groote Schuur Hospital
2016
University of Cape Town
2016
Farr Institute
2016
University of Manchester
2016
Derriford Hospital
2016
The World Health Organization has adopted a resolution on improving the prevention, diagnosis, and management of sepsis. Millions lives can be saved if politicians, policymakers, health care administrators, researchers, clinicians take coordinated actions.
<h3>Background</h3> Severe sepsis is likely to account for around 37 000 deaths annually in the UK. Five years after international Surviving Sepsis Campaign (SSC) care bundles were published, standards management of patients with severe are achieved fewer than one seven patients. <h3>Methods</h3> This was a prospective observational cohort study across 500-bed acute general hospital, assess delivery and impact two interventions: SSC resuscitation bundle new intervention designed facilitate...
Acute rheumatic fever (ARF) and heart disease (RHD) remain major causes of failure, stroke death among African women children, despite being preventable imminently treatable.From 21 to 22 February 2015, the Social Cluster Africa Union Commission (AUC) hosted a consultation with RHD experts convened by Pan-African Society Cardiology (PASCAR) in Addis Ababa, Ethiopia, develop 'roadmap' key actions that need be taken governments eliminate ARF eradicate Africa.Seven priority areas for action...
ObjectiveThe huge burden of inaccurate penicillin allergy labels (PALs) is an important driver antimicrobial resistance. This magnified by insufficient specialists and lack 'point-of-care' tests. We investigated the feasibility non-allergy healthcare professionals (HCPs) delivering direct oral challenges (DPCs) for de-labelling.MethodsThis prospective observational study was conducted in three hospitals England across settings (acute medical, pre-surgical haematology-oncology). Patients with...
In this study, we aim to describe the post-sepsis syndrome from perspective of sepsis survivors. The study is a prospective, observational online international survey. Sepsis survivors enrolled via social media 13 September 2014 2016. None. Physiologic, physical and psychological function post-sepsis; patient satisfaction with sepsis-centered care. 1731 completed surveys 41 countries were analyzed, 79.9% female respondents, age 47.6 ± 14.4 years. majority respondents (47.8%) had within last...
Sepsis, worldwide the leading cause of death in children, has now been recognized as global health emergency it is. On May 26, 2017, World Health Assembly, decision-making body Organization, adopted a resolution proposed by Global Sepsis Alliance to improve prevention, diagnosis, and management sepsis.To discuss implications this for children worldwide.The highlights sepsis threat urges 194 United Nations member states take specific actions implement appropriate measures reduce its human...
Sepsis is associated with significant morbidity and mortality if not promptly recognized treated. Since the development of early goal-directed therapy, rates have decreased, but sepsis remains a major cause death in patients arriving at emergency department or staying hospital. In this forum article, we asked clinicians researchers expertise care to discuss importance rapid detection treatment condition, as well special considerations different patient groups.
Sepsis kills more people than lung cancer, and bowel breast cancer put together. The costs to the NHS are significant; it is estimated that in Europe, patients with severe sepsis cost healthcare funders around 7.6 billion euros per year (Daniels et al, 2007). Costs United States at $16 annually (Angus 2001), Kingdom up 46% of intensive care unit (ICU) bed days used by (Padkin 2003), each ICU costing £1700 day. In 2002 an international campaign was launched: Surviving Campaign. main aim this...
Prehospital staff have made a significant contribution in recent years to improving care for patients with acute coronary syndrome, multiple trauma and stroke. There is, however, another group of that is not currently being targeted, similar time-critical condition. This those severe sepsis septic shock they could also benefit greatly from timely prehospital care. article will consider how can improve the outcome sepsis, particular aid emergency departments identifying initiating treatment sepsis.
<h3>Background</h3> Severe sepsis/septic shock (SS/SS) has a high mortality. The past decade lays witness to concerted international effort tackle this problem through the Surviving Sepsis Campaign (SSC). However, bundle delivery remains problematic. In 2009, College of Emergency Medicine (CEM) set out guidelines for management SS/SS. These standards audit. <h3>Objectives</h3> To assess recognition and patients presenting with SS/SS across three emergency departments (EDs) within West...
Some text in this abstract has been adapted from Krishna MT, Bhogal R, Ng BY, Kildonaviciute K, Jani YH, Williams I, et al . A multicentre observational study to investigate feasibility of a direct oral penicillin challenge de-labelling ‘low risk’ patients with allergy by non-allergy healthcare professionals (SPACE study): Implications for systems. J Infect 2024; 88 :106116. https://doi.org/10.1016/j.jinf.2024.01.015. This is an Open Access article distributed accordance the terms Creative...
Background Sepsis is a common cause of serious illness and death. management remains challenging suboptimal. To support rapid sepsis diagnosis treatment, screening tools have been embedded into hospital digital systems to appear as alerts. The implementation alerts improve the deterioration complex intervention that has fit with team workflow views practices staff. Despite importance human decision-making behavior in optimal implementation, there are limited qualitative studies explore...
The fight against sepsis is an ongoing healthcare challenge, where digital tools are increasingly used with some promising results. experience of survivors and their family members can help optimize alerts for sepsis/deterioration. This study pairs the experiences journey knowledge views on role alerts. A qualitative online, semi-structured interviews focus groups in England. Data were analyzed inductively using thematic analysis. We included 11 survivors, 5 recruited via charities other...
Worldwide, sepsis is one of the most common deadly diseases.It few conditions to strike with equal ferocity in resource-poor areas and developed world.Globally, 20 30 million patients are estimated be afflicted every year.Every hour, about 1,000 people each day around 24,000 die from worldwide.Despite accounting for over 8 lives lost annually, it least well known diseases.In developing world, accounts 60-80% childhood, more than 6 neonates children affected by annually.Sepsis responsible...
Abstract Background Evidence-based interventions may reduce mortality in surgical patients. This study documented the prevalence of sepsis, adherence to guidelines its management, and timing source control general patients presenting as an emergency. Methods Patients aged 16 years or more with emergency surgery problems were identified over a 7-day period then screened for sepsis compliance (using Sepsis Six standards, devised severe sepsis) (whether radiological surgical). Exploratory...
Over 95% of penicillin allergy labels are inaccurate and may be addressed in low-risk patients using direct oral challenge (DPC). This study explored the behaviour, attitudes acceptability patients, healthcare professionals (HCPs) managers DPC patients.