A5076761071- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Antibiotic Resistance in Bacteria
- Tuberculosis Research and Epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Bacterial Infections and Vaccines
- COVID-19 and Mental Health
- Mycobacterium research and diagnosis
- Antibiotic Use and Resistance
- HIV Research and Treatment
- Antimicrobial Resistance in Staphylococcus
- SARS-CoV-2 and COVID-19 Research
- Streptococcal Infections and Treatments
- Hepatitis C virus research
- Urinary Tract Infections Management
- Infective Endocarditis Diagnosis and Management
- COVID-19 and healthcare impacts
- Infectious Diseases and Mycology
- Vibrio bacteria research studies
- HIV/AIDS drug development and treatment
- Ear Surgery and Otitis Media
- Burkholderia infections and melioidosis
- Parasitic infections in humans and animals
- Intramuscular injections and effects
- Infectious Aortic and Vascular Conditions
Ospedale Garibaldi
2020-2025
University of Catania
2020-2025
Azienda USL di Bologna
2023-2024
University of Bologna
2023-2024
Policlinico S.Orsola-Malpighi
2024
University of Messina
2021-2023
Ospedale Cannizzaro
2021
Sapienza University of Rome
1988
Lack of specific definitions clinical characteristics, disease severity, and risk preventive factors post-COVID-19 syndrome (PCS) severely impacts research discovery new therapeutics drugs.This prospective multicenter cohort study was conducted from February 2020 to June 2022 in 5 countries, enrolling SARS-CoV-2 out- in-patients followed at 3-, 6-, 12-month diagnosis, with assessment biochemical features, antibody (Ab) response, Variant Concern (VoC), physical mental quality life (QoL)....
Since late December 2019, severe acute respiratory syndrome coronavirus 2 has spread across the world, which resulted in World Health Organization declaring a global pandemic. Coronavirus disease 2019 (COVID-19) presents highly variable spectrum with regard to severity of illness. Most infected individuals exhibit mild moderate illness (81%); however, 14% have serious and 5% develop distress (ARDS), requiring intensive care support. The mortality rate COVID-19 continues rise world. Data...
HCV treatment became available for all infected patients regardless of their comorbidities, especially HIV coinfected subjects, leading to an improvement in both clinical and immunological conditions. We retrospectively analyzed a cohort HIV/HCV treated with DAA therapies; data regarding epidemiological, viral-immunological, hepatic parameters before after administration have been collected. Drug-drug interactions between antiretroviral therapy non-ART-drugs were also evaluated; the study...
Abstract Background Performance of active screening for multidrug‐resistant Gram‐negative bacteria (MDR‐GNB) and administration targeted antibiotic prophylaxis (TAP) in colonized patients undergoing liver (LT) and/or kidney transplantation (KT) are controversial issues. Methods Self‐administered electronic cross‐sectional survey disseminated from January to February 2022. Questionnaire consisted four parts: hospital/transplant program characteristics, standard prophylaxis, clinical vignettes...
Acute Otitis Media (AOM) typically affects previously healthy children and can be recurrent. This inter-society consensus aims to provide evidence-based recommendations for the antibiotic therapy of mild, severe recurrent otitis media in Italy.A systematic literature review was conducted identify most recent/relevant evidence. The Embase, Scopus, PubMed, Cochrane databases were used with terms "children," "acute media", "recurrent "antibiotics," from 2012 April 2024, no language...
Among nucleos(t)ide analogue therapies for hepatitis B virus (HBV) treatment, entecavir (ETV) and tenofovir disoproxil fumarate (TDF)/tenofovir alafenamide are associated with the lowest rate of drug resistance. ETV is a requiring at least three substitutions in reverse transcriptase (RT) domain to develop resistance, which rare occasion treatment‑naïve patients. However, pre‑existing or acquired single mutations RT could lead virological breakthrough, after viral suppression. The present...
Although the mortality rate among individuals diagnosed during pre-Highly Active Antiretroviral Treatment era has been substantial, a considerable number of them survived. Our study aimed to evaluate prevalence HIV long-term survivors in cohort People Living with between 1985 and 1994 speculate about potential predictive factors associated long survival. This is retrospective single-center study. Subjects surviving more than 300 months (25 years) from diagnosis were defined as Long Term...
Nontuberculous mycobacteria (NTM) infections still represent a large group of insidious diseases hard to deal with. Traditionally, immunocompromised patients suffer from NTM infections, especially with respiratory involvement or disseminated due MAC (Mycobacterium avium complex). Here we report rare case Mycobacterium intracellulare infection involving skin and soft tissue, manifested as chronic cutaneous ulcer in an immunocompetent patient several comorbidities, including seizures. Accurate...
Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has been shown to increase the risk of thrombotic events due a hypercoagulable state caused by several factors. The case 59-year-old woman affected hypertension and metabolic disorders, treated for COVID-19 infection who developed cardiac symptoms during first days hospitalization is reported. Electrocardiogram analysis cardiac-ultrasound confirmed ST-segment elevation myocardial infarction (STEMI) diagnosis, thus patient underwent...
Enterococcus faecalis infective endocarditis (EFIE) continues to be a very serious disease, showing considerable morbidity and mortality rates which are influenced by the spread of multi-drug resistant strains occurred in last decades. Although aminoglycosides were considered treatment choice EIFE, recent years several studies have investigated alternative therapeutic approaches, including combinations beta-lactams, mainly because aminoglycoside-renowned nephrotoxicity widespread development...
Patients with sickle cell disease (SCD) are more susceptible to severe coronavirus 2019 (COVID‑19) infection, in comparison the general population, due possibility that inflammatory state, along hypoxia and hypercoagulability may increase risk of developing acute SCD‑related complications. The present study reports case a 33‑year‑old female affected by SCD, who although vaccinated against COVID‑19, tested positive for SARS‑CoV‑2 developed febrile pneumonia. During hospitalization, patient...
BACKGROUND:Nontuberculous mycobacteria (NTM) are environmental pathogens that cause an increasing number of diseases, in particular immunosuppressed patients. Diagnosing NTM infections may be difficult because clinical presentation is unspecific and resembles other conditions such as tuberculosis, lymphomas, or septicemia. CASE REPORT:We report the case a 62-year-old male with recent history autologous bone marrow transplantation for follicular lymphoma admitted to our department...
Background: A large number of central nervous system impairments occur in subjects with chronic HCV infection regardless liver disease. Brain-derived neurotrophic factor (BDNF) plays an essential role the adult brain concerning its development and proper functioning. Our study aimed at contributing to discussion on involvement BDNF neurocognitive disorders associated infection. Objectives: We evaluate prevalence a cohort HCV-infected subjects, measure serum levels same according degree...
ObjectiveFrom 2011 to 2017, the total number of refugees arriving in Europe, particularly Italy, climbed dramatically. Our aim was diagnose pulmonary TB migrants coming from African coast using a clinical-based port arrival (PoA) screening program.MethodsFrom 2016 2018, via Mediterranean Route were screened for body temperature and presence cough directly on dock: if they feverish with productive cough, their sputum examined NAAT; dry underwent Chest-X-ray (CXR). Those positive NAAT or CXR...
L'articolo esplora la complessità delle separazioni e dei divorzi, evidenziando le differenze tra il distacco emotivo percorso legale che non sempre procedono si risolvono in contem-poranea. Queste fanno sì possano essere rapide o interminabili, a seconda della questioni legali emotive coinvolte. Al supporto è ne-cessario, quindi, affiancare anche una consulenza psicologica finanziaria per affrontare queste situazioni, ma spesso viene trascurato, rendendo lavoro dell'avvocato fami-liarista...
Heart infections are not limited to infectious endocarditis. In fact, prosthetic vascular graft among the most severe complications associated with and cardiac surgery. The risk of developing an infection on material is estimated be ~5%. mortality rate ~10‑25% within 30 days 50% after 1 year. present article describes a case methicillin‑sensitive <em>Staphylococcus aureus</em> (MSSA) following heart Fontan procedure. To best our knowledge, only one other extracardiac prosthesis‑related...