Alper Şener
A5037858197- Hepatitis B Virus Studies
- Hepatitis C virus research
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Infection Control in Healthcare
- Infectious Diseases and Tuberculosis
- Diabetic Foot Ulcer Assessment and Management
- Hepatitis Viruses Studies and Epidemiology
- Nosocomial Infections in ICU
- Dermatological and COVID-19 studies
- COVID-19 and Mental Health
- Infective Endocarditis Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Bacillus and Francisella bacterial research
- Bacterial Infections and Vaccines
- Surgical site infection prevention
- Syphilis Diagnosis and Treatment
- Streptococcal Infections and Treatments
- Sepsis Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Antimicrobial Resistance in Staphylococcus
Izmir University
2025
Izmir Kâtip Çelebi University
2021-2024
Çanakkale Onsekiz Mart Üniversitesi
2015-2024
Sağlık Bilimleri Üniversitesi
2022
Weatherford College
2022
Acıbadem Adana Hospital
2021
Sivas State Hospital
2019
Ege University
2012-2016
University of Maryland Medical Center
2008
University of Maryland, Baltimore
2008
Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report results of International Infection Control Consortium (INICC) study conducted Turkey from August 2003 through October 2012. A DA-HAI surveillance 63 adult, paediatric ICUs and neonatal (NICUs) 29 hospitals, 19 cities using methods definitions U.S. NHSN INICC methods. collected prospective data 94,498 ICU patients for 647,316 bed days. Pooled...
BackgroundThe aim of this study was to delineate mortality indicators in pneumococcal meningitis with special emphasis on therapeutic implications.MethodsThis retrospective, multicenter cohort involved a 15-year period (1998–2012). Culture-positive cases (n = 306) were included solely from 38 centers.ResultsFifty-eight patients received ceftriaxone plus vancomycin empirically. The rest given third-generation cephalosporin alone. Overall, 246 (79.1%) isolates found be penicillin-susceptible,...
Objective: Treponema pallidum and HIV are transmitted frequently through sexual contact, these agents with epidemiological similarities co-infect the same host. The current number of HIV-infected cases in Turkey is increasing. For this reason, we aimed to reveal characteristics syphilis HIV/AIDS cases. Methods: A retrospective longitudinal cohort study was performed, patients were followed up at 24 clinics 16 cities from all seven regions between January 2010 April 2018. We examined...
Objective: The aim of this study was to analyze the temporal trends HIV epidemiology in Turkey from 2011 2016. Method: Thirty-four teams 28 centers at 17 different cities participated retrospective study. Participating were asked complete a structured form containing questions about epidemiologic, demographic and clinical characteristics patients presented with new diagnosis between Demographic data all (complete or partial) included analyses. For cascade care analysis, 15 that provided full...
ABSTRACT Aim This study aimed to determine the important features and cut‐off values after demonstrating detectability of cirrhosis using routine laboratory test results chronic hepatitis C (CHC) patients in machine learning (ML) algorithms. Methods retrospective multicenter (37 referral centers) included data obtained from Hepatitis Turkey registry 1164 with biopsy‐proven CHC. Three different ML algorithms were used classify presence/absence determined features. Results The highest...
Abstract Aims and objectives To determine the factors affecting first‐attempt success of peripheral intravenous catheter (PIVC) placement in older emergency department patients. Background In patients who require treatment, establishing a PIVC as fast possible is clinically important. Design This prospective, observational, descriptive study. Methods Using data collection form, researchers questioned both patient nurse performing procedure terms patient‐ operator‐related factors. study...
This multicentre (22 centres in Turkey) retrospective cohort study aimed to assess the clinical outcomes of patients with neutropenic fever and SARS-CoV-2 positivity. Study period was 15 March 2020-15 August 2021. A total 170 cases (58 female, aged 59 ± 15.5 years) that fulfilled inclusion criteria were included study. One-month mortality rate (OMM) 44.8%. The logistic regression analysis showed following significant variables for mentioned dependent variables: (i) achieving PCR negativity:...
Tuberculous meningitis (TBM) caused by Mycobacterium tuberculosis resistant to antituberculosis drugs is an increasingly common clinical problem. This study aimed evaluate drug resistance profiles of TBM isolates in adult patients nine European countries involving 32 centers provide insight into the empiric treatment TBM. was cultured from cerebrospinal fluid (CSF) 142 and tested for susceptibility first-line drugs, streptomycin (SM), isoniazid (INH), rifampicin (RIF) ethambutol (EMB)....
Abstract Background Tuberculous meningitis (TBM) represents a diagnostic and management challenge to clinicians. The “ Thwaites’ system” “Lancet consensus scoring are utilized differentiate TBM from bacterial but their utility in subacute chronic where is an important consideration unknown. Methods A multicenter retrospective study of adults with meningitis, defined by symptoms greater than 5 days less 30 for (SAM) (CM). “Thwaites’ scores the accuracy sensitivity, specificity, area under...
The ethanolic extracts obtained from the leaves of Verbascum sinuatum L. (Scrophulariaceae) were investigated for their antimicrobial activities against pathogens causing complicated urine tract infection (Enterococcus faecalis, Escherichia coli, Klebsiella pnemoniae, Pseudomonas aeruginosa, Proteus mirabilisand Candida albicans) disk diffusion method and microdilution method. Some antibacterial antifungal antibiotics used as a positive reference standard to determine sensitivity of strains....
Background: Before the introduction of direct-acting antivirals in treatment chronic hepatitis C patients, combination peginterferon alpha and ribavirin was standard therapy.Observational studies that investigated sustained virological response (SVR) rates by these drugs yielded different outcomes.Aims: The goal study to demonstrate real life data concerning SVR rate achieved plus patients who were treatment-naïve.Study Design: A multicenter, retrospective observational study. Methods:The...
Aims: There is no report on the factors affecting resolution of symptoms related to meningitis during treatment tuberculous (TBM). Thus, we examined associated with early therapeutic responses.Materials and Methods: This multicenter study included 507 patients microbiologically confirmed TBM. However, 94 eligible for analysis were in this from 24 centers. Six out died statistical was performed 88 survivors. Early late responder groups compared analysis. P < 0.05 considered show a significant...