A5101487228- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- HIV Research and Treatment
- COVID-19 Clinical Research Studies
- HIV, Drug Use, Sexual Risk
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Syphilis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Cytomegalovirus and herpesvirus research
- Hepatitis Viruses Studies and Epidemiology
- Infectious Diseases and Tuberculosis
- Bacteriophages and microbial interactions
- COVID-19 diagnosis using AI
- Islamic Thought and Society Studies
- Viral gastroenteritis research and epidemiology
- Sex work and related issues
- Bayesian Modeling and Causal Inference
- Phytochemicals and Antioxidant Activities
- Orthopedic Infections and Treatments
- Ottoman and Turkish Studies
Antalya IVF
2020-2025
Akdeniz University
2025
Antalya Eğitim ve Araştırma Hastanesi
2018-2024
Akdeniz University Hospital
2023-2024
Sağlık Bilimleri Üniversitesi
2018-2022
Gazi University
2021
Antalya Bilim University
2021
Objectives. The outbreak of coronavirus disease 2019 (COVID-19) was first reported in December 2019. Until now, many drugs and methods have been used the treatment disease. However, no effective option has found only case-based successes achieved so far. This study aims to evaluate COVID-19 options using multicriteria decision-making (MCDM) techniques. Methods. In this study, we evaluated available by MCDM techniques, namely, fuzzy PROMETHEE VIKOR. These techniques are based on evaluation...
Objective: Treponema pallidum and HIV are transmitted frequently through sexual contact, these agents with epidemiological similarities co-infect the same host. The current number of HIV-infected cases in Turkey is increasing. For this reason, we aimed to reveal characteristics syphilis HIV/AIDS cases. Methods: A retrospective longitudinal cohort study was performed, patients were followed up at 24 clinics 16 cities from all seven regions between January 2010 April 2018. We examined...
In December 2019, cases of pneumonia were detected in Wuhan, China, which caused by the highly contagious coronavirus. This study is aimed at comparing confusion regarding selection effective diagnostic methods to make a mutual comparison among existing SARS-CoV-2 tests and determining most one. Based on available published evidence clinical practice, coronavirus disease (COVID-19) evaluated multi-criteria decision-making (MCDM) methods, namely, fuzzy preference ranking organization method...
Background: About 10% of individuals with latent tuberculosis infection (LTBI) develop (TB) disease during their lifetime. People living HIV (PLWH) have a significantly higher risk developing from compared to those without HIV. Many treatment guidelines recommend screening and treating for LTBI. Objective: This study aimed investigate the LTBI frequency PLWH rates development follow-up. Methods: A total 483 were admitted 3 research hospitals between January 2005 April 2020. Patients who 18...
ABSTRACT Aim This study aimed to determine the important features and cut‐off values after demonstrating detectability of cirrhosis using routine laboratory test results chronic hepatitis C (CHC) patients in machine learning (ML) algorithms. Methods retrospective multicenter (37 referral centers) included data obtained from Hepatitis Turkey registry 1164 with biopsy‐proven CHC. Three different ML algorithms were used classify presence/absence determined features. Results The highest...
Background: In chronic hepatitis B patients with or exposed to the risk of osteoporosis renal dysfunction, switching from tenofovir disoproxil fumarate (TDF) alafenamide (TAF) entecavir (ETV) may be right choice. Objectives: This study aimed present real-life data in terms efficacy and safety a TAF/ETV treatment change while receiving TDF. Methods: retrospective was conducted on 344 adult 10 centers. The who had changed ETV (n = 107) TAF 237) TDF were analyzed. collected at 0 6 months...
Rapid initiation of antiretroviral therapy (ART) reduces the transmission HIV infection in community. This study aimed to determine whether rapid ART is effective compared standard treatment our country.Patients were grouped based on time initiation. RNA levels, CD+4 T cell count, CD4/CD8 ratio, and regimens recorded at baseline follow-up visits for 12 months.There 368-ART naive adults (treatment initiated diagnosis; 143 first day, 48 second-seventh 177 after seventh day). Although...
Human immunodeficiency virus (HIV)/acquired immundeficiency syndrome (AIDS) is a critical global public health problem that significantly affects both life expectancy and the overall quality of individuals in all age groups. The landscape HIV infection has changed recent years due to introduction effective combination antiretroviral therapies (ART). A key component first-line ART regimens for treatment abacavir, nucleoside reverse transcriptase inhibitor. Although abacavir suppressing viral...
With the use of fuzzy PROMETHEE method, current study analysed and evaluated preferred alternative post-exposure prophylaxis (PEP) regimens that can be used in infants children. PEP is a combination anti-HIV drugs prescribed after possible exposure to HIV infection with aim preventing infection. The method multi-criteria decision maker technique which allows mutual comparison different alternatives system. Thus, were using this their corresponding parameters. relative importance (weights)...
Chronic hepatitis C (CHC) is now a more curable disease with new direct acting antivirals (DAA). Although high sustained virologic response rates, failures still occur in DAA regimens. Our objective this study was to characterize the real-life presence of clinically relevant resistance - associated substitutions (RASs) HCV NS5A gene CHC patients whose regimen has failed.The enrolled 53 who experienced failure as prospective longitudinal cohort between 2017-2019. Genotypic testing performed...
By using the PROMETHEE technique, we have evaluated available HIV pediatric antiretroviral drug regimens in three different groups of children which are from ≥3 years to <;6 old, ≥6 <;12 and; ≥ 12 and older, with sexual maturity rating (SMR) 1-3. This technique is a multi-criteria decision maker that mutually compares options. The most frequently used were for determined aged analysed corresponding their parameters by technique. Linguistic fuzzy scale was order evaluate compare between...
In this study, we analyzed the best treatment options in HIV pediatric cases among many antiretroviral drug combinations and each combination has different properties. Such can cause confusion for physicians practice. For aim, proposed fuzzy PROMETHEE technique, a multi-criteria decision-making technique based on mutual comparison of options. The most common used treatments (for infants children aged less than 3 years) were evaluated compared corresponding to their parameters by technique....
In the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), reverse transcriptase-PCR (RT-PCR) technique is often used. We evaluated compatibility SARS-CoV-2 RT-PCR kits containing different gene targets during pandemic.Samples were tested by Bio-Speddy® (RdRp gene) and Diagnovital® + E genes). The correlation between two assays determined Deming regression analysis chi-square analyses.Diagnovital PCR kit showed amplification in a narrow Ct range conveniently sharper...
Integrase strand transfer inhibitors (INSTIs) are currently the standard of practice for first-line HIV therapy most patients. We evaluated mutations associated with INSTI resistance in naive HIV-1 infected patients and treated them antiretrovirals (ART).The study, conducted 2018 - 2020 period, included 50 ART-naïve patients, 69 free ART-experienced 82 INSTI-experienced were interpreted using Stanford University HIVdb Program algorithm.INSTI was not detected ART naïve At least one mutation...
Single-tablet regimens (STRs) can increase treatment success and even improve the quality of life human immunodeficiency virus (HIV) patients. In this study, we aim to analyze real-life efficacy tolerability data people living with HIV (PLWH) initiated on or switched bictegravir/emtricitabine/tenofovir alafenamide fumarate (BIC/FTC/TAF) as first-line treatment.This retrospective analysis was performed in HIV-1-positive patients who were BIC/FTC/TAF clinic between June 2020 2022. Patients...
Chronic inflammation that contributes to the deterioration of mechanical form both vascular wall and function endothelial has been shown cause dysfunction in patients with human immunodeficiency virus (HIV). Nailfold videocapillaroscopy (NVC) is a noninvasive simple technique used analyze dermal microvasculature. The aims our study were detect morphological functional properties microcirculation HIV-positive utilizing NVC compare results those obtained from healthy individuals investigate...
HIV infection increase the risk of serious disease resulting from common vaccine-preventable infections. Vaccinations are particularly important for infected adults. We aimed to investigate immunity rates against measles, mumps, rubella, hepatitis A, B, and tetanus in newly diagnosed patients.Patients who admitted outpatient clinics three centers with infection, between 1 January 2015 31 June 2017 were included. Measles, varicella zoster virus, antibody levels measured by commercial...
The number and proportion of elderly patients living with chronic hepatitis C are expected to increase in the coming years. We aimed compare real-world efficacy safety direct-acting antiviral treatment younger Turkish adults infected C.In this multicenter prospective study, 2629 eligible treated antivirals between April 2017 December 2019 from 37 referral centers were divided into 2 age groups: (≥65 years) (<65 their was compared groups evaluable population. Then, by matching for...
Bu çalışmada, Hatay’da farklı bölgelerde yetiştirilen Halhalı türü zeytin (Olea europaea)ağaçlarının yapraklarının metanol ekstraktlarının antioksidan aktiviteleri belirlenmiştir. Toplam fenolik madde miktarları Folin-Ciocaltaeu yöntemi ile tayin edilmiştir. Antioksidan özelliklerini belirlemek için kullanılan diğer yöntemler DPPH radikal süpürme yöntemi, FRAP indirgeme gücü metodu ve β-karoten-linoleik asit emülsiyon yöntemidir. Sonuçlar standart antioksidanlar (BHA, BHT) kıyaslanmıştır....
<b><i>Objective:</i></b> In recent years, there has been worldwide recognition of the problems associated with Human Immunodeficiency Virus (HIV) infection and Acquired Immune Deficiency Syndrome (AIDS). The prevalence cardiovascular disease in HIV-infected population is increasing. Repolarization abnormalities, significant contributor to life-threatening arrhythmias mortality, are most frequent electrocardiographic changes this population. This study aimed evaluate...
To effectively control the HIV epidemic and meet global targets, policymakers recommend rapid initiation of antiretroviral therapy (ART). Our study aims to investigate effect ART programs on individuals diagnosed with HIV, considering varying coverage days after diagnosis, compare it standard-of-care treatment in Turkey. We used a dynamic compartmental model simulate dynamics infection Rapid treatment, defined as within 7 was contrasted which starts 30 diagnosis. This considered three levels...
Introduction: Coronavirus diseases-2019 (COVID-19) have been ongoing for more than two years.Despite the scientific research conducted in this process, there is still no widely accepted definitive treatment disease.For treating COVID-19, using antiviral agents previously used of other RNA-virus infections has seen as a fast way to solution, and favipiravir one leading agents.This prospective, multicenter, observational study was designed investigate safety 500 patients treated with...