Yeşim Yıldız

ORCID: 0000-0003-3006-4112
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • COVID-19 and Mental Health
  • Vaccine Coverage and Hesitancy
  • HIV/AIDS Research and Interventions
  • HIV, Drug Use, Sexual Risk
  • Nosocomial Infections in ICU
  • Recreation, Leisure, Wilderness Management
  • Family and Patient Care in Intensive Care Units
  • Cancer Immunotherapy and Biomarkers
  • Respiratory viral infections research
  • Pneumonia and Respiratory Infections
  • COVID-19 Impact on Reproduction
  • COVID-19 and healthcare impacts
  • Oral and Maxillofacial Pathology
  • Ottoman and Turkish Studies
  • Liver Disease Diagnosis and Treatment
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Diverse Aspects of Tourism Research
  • Patient Satisfaction in Healthcare
  • Tumors and Oncological Cases
  • Apelin-related biomedical research

Gazi University
2015-2025

Bridge University
2024

Gazi Hastanesi
2024

Inonu University
2023

European Society of Clinical Microbiology and Infectious Diseases
2023

Ankara (Czechia)
2022

Mardin Artuklu University
2019-2021

Selçuk Üniversitesi Tıp Fakültesi Hastanesi
2019-2020

Istanbul University
2020

Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi
2020

Interleukin 40 (IL-40) is a novel cytokine that has been associated with B lymphocytes, particularly IgA-secreting cells in gut mucosa. Considering mucosal association of IL-40, we aimed to determine serum IL-40 levels patients Covid-19. We compared concentrations healthy people both mild symptoms SARS-CoV-2 infection and pneumonia. was measured by ELISA. Serum IgA were tested nephelometry. For the first time, demonstrated increased significantly. The elevation related severity infection....

10.1371/journal.pone.0321578 article EN cc-by PLoS ONE 2025-05-02

Background: In chronic hepatitis B patients with or exposed to the risk of osteoporosis renal dysfunction, switching from tenofovir disoproxil fumarate (TDF) alafenamide (TAF) entecavir (ETV) may be right choice. Objectives: This study aimed present real-life data in terms efficacy and safety a TAF/ETV treatment change while receiving TDF. Methods: retrospective was conducted on 344 adult 10 centers. The who had changed ETV (n = 107) TAF 237) TDF were analyzed. collected at 0 6 months...

10.5812/hepatmon.118721 article EN Hepatitis Monthly 2022-01-09

Introduction The efficacy of immune checkpoint inhibitors (ICIs) against malignant melanoma and numerously solid tumors has been demonstrated in several clinical studies. incidence immune-related adverse effects (irAEs) increased after the rapidly expanding indications applications ICIs. We present a case nivolumab ipilimumab-induced encephalitis with worsening consciousness full recovery following ICIs suspension high-dose steroid coupled intravenous immunoglobulin (IVIG). Case Report A...

10.1177/10781552221118529 article EN Journal of Oncology Pharmacy Practice 2022-08-08

ABSTRACT We aimed to investigate the immune responses homologous and heterologous COVID‐19 booster vaccinations in renal transplant recipients (RTRs) identify factors affecting these responses. In this prospective multicenter observational study, we measured antibody kinetics of 90 RTRs using chemiluminescent microparticle immunoassay method. The mean age participants was 45.2 ± 11.4 years, with 35.6% being female. On 42nd day after first vaccine dose, median level 16.7 (IQR 2.5−249.5)...

10.1002/jmv.70030 article EN cc-by-nc-nd Journal of Medical Virology 2024-10-28

Objective: There are many difficulties in diagnosing and treating Stenotrophomonas maltophilia bacteremia. In this study, we aimed to evaluate “true” “false-positive bacteremia” assess mortality risk factors the impact of different treatment regimens. Materials Methods: Hospitalized adult patients with S. maltophilia-positive blood cultures were assessed by a two-stage analysis. First, clinical significance was assessed, divided into groups. Then, excluding false positives, analyzed...

10.36519/idcm.2022.187 article EN cc-by-nc Infectious Diseases and Clinical Microbiology 2022-12-21

ObjectivesThis study aimed to evaluate the long-term antibody kinetics after vaccinating with an inactivated COVID-19 Vero cell vaccine (CoronaVac) in healthcare workers (HCWs) at a single center Turkey.MethodsFor this prospective observational study, Chemiluminescence immunoassay (CLIA) and enzyme-linked immunosorbent assay (ELISA) were used for determination of binding antibodies (bAb) neutralizing (nAb), respectively. Antibody compared potential influencing factors, propensity score...

10.1016/j.ijid.2022.05.007 article EN cc-by-nc-nd International Journal of Infectious Diseases 2022-05-11

Objective: We aimed to investigate the vaccination status and risk factors for intensive care unit (ICU) support need of laboratory-confirmed breakthrough COVID-19 infection inpatients. Materials Methods: This multi-center point-prevalence study was conducted on inpatients, divided into two groups as ‘fully’ ‘partially’ vaccinated according status. Results: Totally 516 patients were included in study. The median age 65 (55-77), 53.5% (n=276) male. Hypertension (41.9%, n=216), diabetes...

10.36519/idcm.2023.216 article EN cc-by-nc Infectious Diseases and Clinical Microbiology 2023-06-23

To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired (CAP) in Turkey and to investigate compare features PP non-PP CAP patients.This multicenter, non-interventional, prospective, observational study included adult (age ≥ 18 years). Diagnosis was based on presence at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum urinary antigen [UAT]) radiographic findings pneumonia.Four hundred sixty-five were diagnosed...

10.5152/turkthoracj.2021.20223 article EN Turkish Thoracic Journal 2021-07-14

Amaç: Aşı tereddüdü hem Türkiye de dünya için toplumsal tehdit oluşturan bir tutumdur. Bu konuda Türkçeye validasyonu yapılmış ölçek bulunmamaktadır. çalışmanın amacı Opel ve ark. tarafından 2011 yılında geliştirilip 2013 revize edilen ‘Parent Attitudes About Childhood Vaccines Survey ‘isimli ölçeğin dil validasyonunun yapılmasıdır. Gereç Yöntem : Çalışma çalışması olarak gerçekleştirilmiştir. DJ arkadaşları geliştirilen ‘Seri yöntem’ kullanılarak yapılmıştır. Ölçeğin çeviri, gözden geçirme,...

10.31362/patd.748886 article TR cc-by-nc Pamukkale Medical Journal 2020-07-17

Aim: COVID-19 pandemic has affected all aspects of life. With this study, we aimed to evaluate the effects on quality life (QOL) oncology patients. Material and Methods: This study was conducted 220 outpatients inpatients medical clinics Gazi University Hospital, through face-to-face interviews in period between August 2020 February 2021. Data were collected with WHOQOL Scale original questionnaire. Results: Being younger, being a higher level education, living metropolitan cities, having...

10.18663/tjcl.1460996 article EN Turkish Journal of Clinics and Laboratory 2024-06-29

The uncertain treatment duration for nucleos(t)ide analogues (NA) used in the of chronic hepatitis B (CHB) is an important problem both patients and physicians. aim this study was to evaluate determinants virologic relapse (VR) optimum time discontinuation follow-up CHB who voluntarily discontinued after virological suppression achieved under NA use.

10.1097/meg.0000000000002722 article EN European Journal of Gastroenterology & Hepatology 2024-02-23

Abstract Aim To evaluate the vaccine response and effect of booster dose on COVID‐19 positivity in haemodialysis (HD) peritoneal dialysis (PD) patients who received did not receive BNT162b2 as a after two doses CoronaVac. Methods The study included 80 PD 163 HD patients, had been administered Antibody levels were measured Days 42 90 first dose. Measurements repeated Day 181 that 28 third those also below 50 AU/mL considered negative. Results seropositivity rate was similar group ( p = 0.212...

10.1111/nep.14292 article EN Nephrology 2024-03-14

<title>Abstract</title> Aim: COVID-19 pandemic has affected all aspects of life. With this study, we aimed to evaluate the effects on quality life (QOL) oncology patients. Material and Methods: This study was conducted 220 outpatients inpatients medical clinics Gazi University Hospital, through face-to-face interviews in period between August 2020 February 2021. Data were collected with WHOQOL Scale original questionnaire. Results: Being younger, being a higher level education, living...

10.21203/rs.3.rs-4850956/v1 preprint EN cc-by Research Square (Research Square) 2024-09-02

Excessive inflammatory immune response during SARS-CoV-2 infection contributes to severe disease in COVID-19 patients. Recently, some researchers hypothesized that dysregulation of the bradykinin (BK) system may also play a role pathogenesis disease. Des-Arg(9)-bradykinin (DABK), an active metabolite BK, is responsible for vasodilatation and increased permeability lungs regulated by angiotensin converting enzyme 2 (ACE-2). Viral inhibition ACE-2 increases DABK levels. Serum levels this be...

10.7754/clin.lab.2021.211110 article EN Clinical Laboratory 2022-01-01
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