A5050658473- COVID-19 Clinical Research Studies
- Diphtheria, Corynebacterium, and Tetanus
- Hepatitis B Virus Studies
- Monoclonal and Polyclonal Antibodies Research
- Immunotherapy and Immune Responses
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Clostridium difficile and Clostridium perfringens research
- Circadian rhythm and melatonin
- Hepatitis C virus research
- Gastrointestinal motility and disorders
- Tuberculosis Research and Epidemiology
- Systemic Lupus Erythematosus Research
- Inflammatory Bowel Disease
- Acute Ischemic Stroke Management
- Liver Disease Diagnosis and Treatment
- Influenza Virus Research Studies
- HER2/EGFR in Cancer Research
- Neurological Disorders and Treatments
- Veterinary medicine and infectious diseases
- Pituitary Gland Disorders and Treatments
- Long-Term Effects of COVID-19
- Cerebrovascular and Carotid Artery Diseases
- Infective Endocarditis Diagnosis and Management
- Nosocomial Infections in ICU
Gazi University
2012-2025
Gazi Hastanesi
2012-2021
Zeynep Kamil Hospital
2019
Purpose Cytokines are major mediators of COVID-19 pathogenesis and several them already being regarded as predictive markers for the clinical course outcome cases. A pitfall many cytokine studies is lack a benchmark sampling timing. Since cytokines their relative change during an infectious disease quite dynamic, we evaluated value serially measured Methods In this single-center, prospective study, broad spectrum were determined by multiplex ELISA assay in samples collected at admission...
Interleukin 40 (IL-40) is a novel cytokine that has been associated with B lymphocytes, particularly IgA-secreting cells in gut mucosa. Considering mucosal association of IL-40, we aimed to determine serum IL-40 levels patients Covid-19. We compared concentrations healthy people both mild symptoms SARS-CoV-2 infection and pneumonia. was measured by ELISA. Serum IgA were tested nephelometry. For the first time, demonstrated increased significantly. The elevation related severity infection....
Immunoassays are simple, efficient and reliable means for testing patient samples in the modern hospital. Their specificity sensitivity have provided robust by which detection of analytes can be achieved with ease. The underlying principle antigen-antibody reactions forming a measurable complex exposes immunoassays to possible interference from proteins other reactants structural similarities antibodies or analytes. Accounting test its reliability, impact interferents both endogenous like...
Objective: There may be an association between hyperprolactinemia and autoimmune diseases, possibly because of the immunostimulatory effect prolactin.The aim this study was to investigate prevalence thyroid non-thyroid serum B-cell activating factor (BAFF), proliferation-inducing ligand (APRIL) levels as indicators increased autoimmunity, quality life, depression, anxiety in patients with prolactinoma.Methods: Fifty-six premenopausal women prolactinoma 50 healthy were included...
Abstract We observed significant differences in measured human epidermal growth factor (hEGF) levels for the same individual's serum/plasma samples between different tube types (glass, polystyrene, plastic with clot activator, without EDTA, polypropylene tubes). For all individuals, hEGF plasma were found to be below detection limit. The discrepancy of serum and was attributed platelet derived EGF by analyzing lyzate size exclusion chromotography demonstrating immunoreactivity fractions...
ObjectivesThis study aimed to evaluate the long-term antibody kinetics after vaccinating with an inactivated COVID-19 Vero cell vaccine (CoronaVac) in healthcare workers (HCWs) at a single center Turkey.MethodsFor this prospective observational study, Chemiluminescence immunoassay (CLIA) and enzyme-linked immunosorbent assay (ELISA) were used for determination of binding antibodies (bAb) neutralizing (nAb), respectively. Antibody compared potential influencing factors, propensity score...
Background/aim: The aim of this study was to compare the distribution interstitial Cajal cells, eosinophils, and mast cells in normal inflamed appendices, evaluate correlation presence these with severity inflammation appendicitis. Materials methods: appendicitis group (n = 30) divided further into three groups according macroscopic description histological findings. Ten appendices served as controls. Tissue samples were processed for routine examination. Additionally, all sections...
Objective: To determine the value of patient characteristics, laboratory parameters, and imaging procedures in assessment severity prognosis diabetic foot infections (DFIs). Material Methods: Demographic clinical characteristics 71 patients with DFI were evaluated retrospectively. Patient data including diabetes status wound related information, radiologic findings, outcomes recorded. Results: In between 35 60 years old, frequency recurrent four half-times higher than those over (OR 4.55,...
Abstract A new, very simple method for increasing the sensitivity and recovery rate of enzyme‐linked immunosorbent assay (ELISA) precise quantification antigen in human serum is described. The design uses CATNF6A4c IgG2a monoclonal antibody biotinylated anti‐human tumor necrosis factor‐α (hTNF‐α) polyclonal mouse IgG as capture tracer antibodies, respectively. completed within 4 hours at room temperature capable detecting both recombinant native TNF‐α. incorporates use saturated ammonium...
Diphtheria is of great epidemiological concern. Although mainly observed during childhood, unvaccinated adults and relatively immunocompromised patients are at increased risk for acquiring diphtheria. We aimed to determine the rates certain determinants protection against diphtheria in adult hemodialysis (HD) patients. Protection 322 HD were compared with 65 diabetes mellitus type 2 (DM) healthy controls. A questionnaire was held regard smoking habits alcohol intake. Antibody levels assessed...