A5012083790- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- HER2/EGFR in Cancer Research
- Advanced Breast Cancer Therapies
- Inflammatory Biomarkers in Disease Prognosis
- Renal cell carcinoma treatment
- Cancer Immunotherapy and Biomarkers
- Cancer Treatment and Pharmacology
- Nutrition and Health in Aging
- Ovarian cancer diagnosis and treatment
- Economic and Financial Impacts of Cancer
- Artificial Intelligence in Healthcare and Education
- Esophageal Cancer Research and Treatment
- Radiomics and Machine Learning in Medical Imaging
- GDF15 and Related Biomarkers
- Brain Metastases and Treatment
- Lung Cancer Research Studies
- Peptidase Inhibition and Analysis
- PARP inhibition in cancer therapy
- Head and Neck Cancer Studies
- Cancer, Lipids, and Metabolism
- Multiple and Secondary Primary Cancers
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Macrophage Migration Inhibitory Factor
Memorial Ankara Hospital
2024-2025
Gazi University
2019-2024
Ankara University
2019-2023
Introduction and aim To investigate the effect of prognostic nutritional index on treatment response survival in patients with metastatic renal cell cancer. Methods We retrospectively analyzed modalities; demographic, clinical pathological features 396 RCC index. Based median value, were grouped as having low high values. Kaplan-Meier method was used for analysis, Cox-regression analysis multivariate analysis. Results The overall 39 months (95% CI 26.1–51.8), 28 17.9–38) 7 4.7–9.2)...
This study aims to report the efficacy and safety of capecitabine plus temozolomide (CAPTEM) across different lines treatment in patients with metastatic neuroendocrine tumors (NETs).
This study aims to investigate the prognostic value of systemic immune-inflammation index (SII)and its impact on survival in patients with metastatic renal cell carcinoma (mRCC). A total 706patients mRCC treated tyrosine kinase inhibitors (TKIs)between January 2007 and June 2020 (i.e., sunitinib, pazopanib) were included this study. SII was calculated 621 following formula:[neutrophil (cellsx109/L) x platelet (cellsx109/L)] / lymphocyte (cellsx109/L).All classified into SII-high SII-low...
Background To describe the prognostic value of neutrophil–lymphocyte ratio and its effect on survival in patients with advanced renal cell carcinoma. Methods We retrospectively analyzed 331 patients. The cut-off was specified as “3” which is mostly close—and also clinically easily applicable—to median level our study group. High group identified >3 (n = 160) low ≤3 163). Results A total (with 211 male 120 female) were enrolled to study. age 58. International Metastatic RCC Database...
We aimed to evaluate the relationship between sarcopenia, myosteatosis, and systemic inflammatory response biomarkers their prognostic role in stage 2 3 gastric cancer patients.This study included 84 patients with or who underwent a gastrectomy. Computed tomography scans were used determine skeletal muscle index (SMI) at third lumbar vertebra level for sarcopenia myosteatosis.Based on Asian Working Group of Sarcopenia (AWGS2019) criteria, incidence was 36.9% that myosteatosis 46.4%....
Introduction The efficacy of immune checkpoint inhibitors (ICIs) against malignant melanoma and numerously solid tumors has been demonstrated in several clinical studies. incidence immune-related adverse effects (irAEs) increased after the rapidly expanding indications applications ICIs. We present a case nivolumab ipilimumab-induced encephalitis with worsening consciousness full recovery following ICIs suspension high-dose steroid coupled intravenous immunoglobulin (IVIG). Case Report A...
Introduction:The aim of this retrospective study was to assess the prognostic significance geriatric nutritional risk index (GNRI) for elderly patients diagnosed with early-stage colon cancer.Materials and Methods: Medical records 114 cancer who underwent curative surgery received chemotherapy were analyzed.The calculation GNRI derived from measurement serum albumin levels assessment body weight.Patients divided into two categories: low-GNRI (GNRI: <98), high-GNRI ≥98) compared. Results:The...
AbstractThe aim of our study was to evaluate the association between increased splenic volume (SV) and liver fibrosis indices in colon cancer patients receiving oxaliplatin-based adjuvant chemotherapy. Patients who received regimens with diagnosis stage II III were evaluated. Splenic measurements, function tests, platelet count, non-invasive [NAFLD score (NFS), AST ratio (APRI), Fibrosis-4 (FIB-4)] measured before after treatment. A 30% increase SV chemotherapy compared baseline considered...
Niraparib, a strong poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitor, contributed significantly to progression-free survival as maintenance therapy in the platinum-sensitive period both first-line and recurrent ovarian cancer, regardless of BRCA mutation. Grade 3-4 anemia, which has manageable side effect profile, especially hematological, is seen almost 1 out every 4 patients. To best our knowledge, there been no reported case pure red cell aplasia (PRCA) induced by niraparib...
We aimed to evaluate the efficacy and safety of trastuzumab emtansine in patients with metastatic breast cancer previously treated pertuzumab plus taxane. reviewed medical records who were diagnosed Human Epidermal Growth Factor Receptor 2 (HER-2) positive received then TDM-1 between January 2014 2021 from twenty- five centers. The Kaplan- Meier method estimated progression-free survival (PFS) overall (OS). Additionally, objective response rate (ORR), clinical benefit (CBR), evaluated. One...
Background: Immunotherapy has transformed cancer treatment; however, predicting treatment response remains challenging. Serum biomarkers can help identify patients who are most likely to benefit from immunotherapy. Objective: This study evaluates the relationship between serum growth differentiation factor 15 (GDF-15) and interleukin-6 (IL-6) levels outcomes in undergoing second-line Methods: We conducted a prospective observational involving 85 with non-small-cell lung (NSCLC), renal cell...
Objective This study aimed to assess the efficacy and safety of FOLFIRI paclitaxel in patients with advanced gastric cancer (AGC) who were previously treated first-line modified docetaxel, cisplatin, 5-fluorouracil (mDCF), or 5-fluorouracil, oxaliplatin, docetaxel (FLOT).
The fact that the human epidermal growth factor receptor 2 (HER2)-low group, historically classified as HER2 negative in breast cancer histology, benefited from HER2-targeted treatments similarly to HER2-positive group indicates this has a distinct histology HER2-0 group. effectiveness of cyclin-dependent kinase 4/6 inhibitors, which are standard first-line treatment for hormone receptor-positive, HER2-negative advanced cancer, newly defined histological subgroup remains topic debate. In our...