Şebnem Şenol Akar

ORCID: 0000-0001-7438-7306
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Antifungal resistance and susceptibility
  • Pneumonia and Respiratory Infections
  • Urinary Tract Infections Management
  • Hydrogels: synthesis, properties, applications
  • Antibiotic Resistance in Bacteria
  • Vaccine Coverage and Hesitancy
  • HIV, Drug Use, Sexual Risk
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Streptococcal Infections and Treatments
  • COVID-19 Clinical Research Studies
  • Bacterial Infections and Vaccines
  • Nosocomial Infections in ICU
  • Advanced Drug Delivery Systems
  • Fungal Infections and Studies
  • Urinary Bladder and Prostate Research
  • Advancements in Transdermal Drug Delivery
  • Infectious Diseases and Mycology
  • Infective Endocarditis Diagnosis and Management
  • Pediatric Urology and Nephrology Studies
  • Reproductive System and Pregnancy
  • COVID-19 Impact on Reproduction
  • Infectious Diseases and Tuberculosis
  • Photopolymerization techniques and applications

Manisa Celal Bayar University
2011-2024

Yıldız Technical University
2018-2023

Samsun University
2023

Ege Üniversitesi Tıp Fakültesi Hastanesi
2011

Ege University
2007

AbstractThe aim of this observational prospective study was to compare the effect fosfomycin tromethanol (FT) and carbapenems (meropenem or imipenem cilastatin) in treatment extended-spectrum beta-lactamase (ESBL)- producing Escherichia coli-related complicated lower urinary tract infection (CLUTI). Inclusion criteria were: patients who were aged >18 yr with dysuria problems frequency urgency passing urine; those >20 leukocytes/mm3 urine microscopy culture-proven ESBL-producing carbapenem...

10.1179/joc.2010.22.5.355 article EN Journal of Chemotherapy 2010-10-01

Early and accurate risk prediction is an important clinical demand in patients with infective endocarditis (IE). The platelet-to-lymphocyte ratio (PLR) independent predictor of worse prognosis various cardiovascular diseases. aim this study was to determine the value PLR in-hospital mortality among IE patients. We retrospectively analyzed clinical, laboratory, echocardiographic data 59 adult definite 40 controls. In-hospital occurred 16 (27%) Vegetation size, levels high-sensitive C-reactive...

10.1016/j.kjms.2015.10.004 article EN publisher-specific-oa The Kaohsiung Journal of Medical Sciences 2015-11-07

The aim of this prospective cohort study was to investigate the effect coronavirus disease 2019 (COVID-19) vaccinations on menstrual cycle and ovarian reserve in reproductive aged-women. Health care providers (n = 258) vaccinated with inactivated (CoronaVac) mRNA based (Pfizer-BioNTech®) COVID-19 vaccines were included. All subjects completed a gynaecological history questionnaire Anti-Mullerian Hormone (AMH) levels measured serum samples collected before first vaccination at 1st, 3rd, 6th...

10.1080/14647273.2023.2181710 article EN Human Fertility 2023-01-01

In this study, it was aimed to prospectively evaluate the efficacy, side effects and seroconversion data of inactive severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), CoronaVac® (Sinovac, China) vaccine in healthcare workers. A total 1053 workers who were initially seronegative (COV2T® SARS-CoV-2 Total Siemens, USA) vaccinated with inactivated included study. Quantitative IgG antibodies (ADVIA Centaur® IgG, investigated 28 days after first (n= 939) second 771). addition,...

10.5578/mb.20219705 article EN Mikrobiyoloji Bulteni 2021-10-18

Infectious diseases (ID) trainees should be familiar with duties relevant to consultation practice. In this study we aimed analyze the ID trainee night/weekend shift process in terms of consultant characteristics, types recommendations, and compliance recommendations.All consultations performed by on night at weekends between 10 June August 2004 were recorded prospectively standardized forms. specialists assessed appropriateness recommendations day after each consultation. Recommendations...

10.1016/j.ijid.2007.02.003 article EN publisher-specific-oa International Journal of Infectious Diseases 2007-04-30

Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised patients. Many cases pulmonary, cutaneous, cerebral, paranasal sinus immunocompetent patient were defined literature but disseminated very rare. Here we present an case with extrapulmonary due to Aspergillus niger, totally recovered after effective antifungal treatment voriconazole.

10.1155/2013/385190 article EN cc-by Case Reports in Infectious Diseases 2013-01-01

Abstract The purpose of the present investigation was to prepare pH-sensitive hydrogels from photo-crosslinked poly(ethylene glycol) diacrylate (PEG-DA). Rutile titanium dioxide (TiO 2 ) employed modify PEG-DA hydrogels. rutile nanoparticles were prepared by direct oxidation in presence polyethylene glycol (PEG) at high temperature. characterized FT-IR, XRD and SEM. influence experimental conditions, such as pH, type amount photoinitiators on release profiles donepezil hydrochloride (active...

10.2478/msp-2020-0054 article EN Materials Science-Poland 2020-09-01

Colistin is used as a salvage therapy for multidrug-resistant and extremely drug-resistant gram-negative bacterial infections. Our aim was to evaluate colistin efficiency toxicity in the treatment of these resistant infections.This retrospective study carried out tertiary care hospital during 2011-2013. Study data were collected from medical records consultations infectious diseases clinic.The group included 158 patients with nosocomial infections 136 (86.1%) them hospitalized ICU....

10.3906/sag-1506-125 article EN other-oa TURKISH JOURNAL OF MEDICAL SCIENCES 2016-01-01

In this multicenter prospective cohort study, it was aimed to evaluate the bacterial and viral etiology in community-acquired central nervous system infections by standart bacteriological culture multiplex polymerase chain reaction (PCR) methods. Patients hospitalized with between April 2012 February 2014 were enrolled study. Demographic clinical information of patients collected prospectively. Cerebrospinal fluid (CSF) samples examined methods, PCR (Seeplex meningitis-B ACE Detection...

10.5578/mb.57358 article EN Mikrobiyoloji Bulteni 2017-07-10

Sorption and pervaporation experiments were carried out for pure ethanol, ethyl acetate their binary mixtures using zeolite 13X-filled poly(dimethylsiloxane) membranes prepared by the solution–casting method. The sorption values increased in proportion with amount of mixtures. excess Gibbs free energies activity coefficients calculated UNIFAC method used simultaneously to determine interaction parameters acetate–ethanol mixture. effects temperature feed concentration on flux selectivity...

10.1080/00986445.2021.1940155 article EN Chemical Engineering Communications 2021-06-22

Each year, approximately 125 million people visit malaria-endemic countries. This study aimed to investigate the clinical characteristics of imported Plasmodium falciparum malaria infections in Türkiye.The included patients diagnosed with P. between 1996 and 2022. A retrospective evaluation was conducted on whole blood samples and/or smears, as well detailed medical histories, manifestations, laboratory findings. total 131 cases were study.Among patients, 121 male. Of these, 101 had traveled...

10.4274/tpd.galenos.2023.99815 article TR cc-by-nc-nd Turkish Journal of Parasitology 2023-12-27

The aim of the present study is to develop hydroxyapatite modified PEG-DA and PEG-DA/HEMA based hydrogels for release Donepezil HCl potential treatment Alzheimer’s disease. [2,2-Dimethoxy-2-phenyl-acetophenone] (Irgacure 651), 1 Hydroxycyclohexyl phenyl ketone 184) 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone 2959) were used as photo-initiators in synthesis was modifying hydrogels. Fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM) digital utilized...

10.18596/jotcsa.485817 article EN Journal of the Turkish Chemical Society Section A Chemistry 2019-01-11

Background/aim: Broad-spectrum antibiotics have become available for use only with the approval of infectious disease specialists (IDSs) since 2003 in Turkey. This study aimed to analyze tendencies doctors who are not (non-IDSs) towards restriction antibiotics. Materials and methods: A questionnaire form was prepared, which included a total 22 questions about impact antibiotic (AR) policy, role IDSs restriction, perception this change consumption. The completed by each participating...

10.3906/sag-1405-26 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2016-01-01

Solid organ transplantasyonu (SOT) son dönem yetmezliği olan hastaların yaşam kalitesini ve sağkalım süresini arttıran bir tedavi yöntemidir.Bu hasta gruplarına verilen immünsüpresif tedaviler invazif fungal enfeksiyonların (İFİ) gelişmesine yatkınlık oluşturabilmektedir.SOT alıcılarında İFİ insidansı, transplante edilen organa bağlı olup %5-42 arasında değişmektedir.Transplant yapılan göre değişmekle birlikte en sık izole etken Candida spp.olup bunu Aspergillus spp.takip etmektedir.Gelişen...

10.4274/mjima.2015.7 article TR cc-by-nc-nd Mediterranean Journal of Infection Microbes and Antimicrobials 2015-12-01

: 2-hydroxyl ethyl methacrylate/poly(ethylene glycol) diacrylate (HEMA/PEG-DA) based hydrogels are attractive drug carriers due to their appealing properties such as biodegradability and sustained release. The scope of this study was investigate the swelling release behaviors HEMA/PEG-DA-based filled with low concentrations nanoparticle titanium dioxide (TiO2). Hydrogels have been synthesized successfully by photopolymerization. 2,2-Dimethoxy-2-Phenyl-Acetophenone (Irgacure 651),...

10.31202/ecjse.887855 article EN El-Cezeri Fen ve Mühendislik Dergisi 2021-05-04

<title>Abstract</title> Objectives To determine the epidemiology and prognosis of sepsis in cancer patients influence on mortality patients. Methods In this multicenter, prospective, observational study, hospitalized without followed up until discharge or a maximum 90 days were included. The incidence follow-up period, risk factors for sepsis, 28-day with 90-day entire group determined. Results During 790 Sepsis developed 72 (9.1%) during follow-up. Older age, hospitalization due to any...

10.21203/rs.3.rs-3978336/v1 preprint EN cc-by-nc-sa Research Square (Research Square) 2024-02-27

ÖZ Giriş: Achromobacter xylosoxidans (AX) cinsi bakterilere bağlı gelişen

10.5578/flora.20226565 article TR Flora the Journal of Infectious Diseases and Clinical Microbiology 2022-03-25
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