- SARS-CoV-2 and COVID-19 Research
- Antifungal resistance and susceptibility
- Pneumonia and Respiratory Infections
- Urinary Tract Infections Management
- Hydrogels: synthesis, properties, applications
- Antibiotic Resistance in Bacteria
- Vaccine Coverage and Hesitancy
- HIV, Drug Use, Sexual Risk
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Streptococcal Infections and Treatments
- COVID-19 Clinical Research Studies
- Bacterial Infections and Vaccines
- Nosocomial Infections in ICU
- Advanced Drug Delivery Systems
- Fungal Infections and Studies
- Urinary Bladder and Prostate Research
- Advancements in Transdermal Drug Delivery
- Infectious Diseases and Mycology
- Infective Endocarditis Diagnosis and Management
- Pediatric Urology and Nephrology Studies
- Reproductive System and Pregnancy
- COVID-19 Impact on Reproduction
- Infectious Diseases and Tuberculosis
- Photopolymerization techniques and applications
Manisa Celal Bayar University
2011-2024
Yıldız Technical University
2018-2023
Samsun University
2023
Ege Üniversitesi Tıp Fakültesi Hastanesi
2011
Ege University
2007
AbstractThe aim of this observational prospective study was to compare the effect fosfomycin tromethanol (FT) and carbapenems (meropenem or imipenem cilastatin) in treatment extended-spectrum beta-lactamase (ESBL)- producing Escherichia coli-related complicated lower urinary tract infection (CLUTI). Inclusion criteria were: patients who were aged >18 yr with dysuria problems frequency urgency passing urine; those >20 leukocytes/mm3 urine microscopy culture-proven ESBL-producing carbapenem...
Early and accurate risk prediction is an important clinical demand in patients with infective endocarditis (IE). The platelet-to-lymphocyte ratio (PLR) independent predictor of worse prognosis various cardiovascular diseases. aim this study was to determine the value PLR in-hospital mortality among IE patients. We retrospectively analyzed clinical, laboratory, echocardiographic data 59 adult definite 40 controls. In-hospital occurred 16 (27%) Vegetation size, levels high-sensitive C-reactive...
The aim of this prospective cohort study was to investigate the effect coronavirus disease 2019 (COVID-19) vaccinations on menstrual cycle and ovarian reserve in reproductive aged-women. Health care providers (n = 258) vaccinated with inactivated (CoronaVac) mRNA based (Pfizer-BioNTech®) COVID-19 vaccines were included. All subjects completed a gynaecological history questionnaire Anti-Mullerian Hormone (AMH) levels measured serum samples collected before first vaccination at 1st, 3rd, 6th...
In this study, it was aimed to prospectively evaluate the efficacy, side effects and seroconversion data of inactive severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), CoronaVac® (Sinovac, China) vaccine in healthcare workers. A total 1053 workers who were initially seronegative (COV2T® SARS-CoV-2 Total Siemens, USA) vaccinated with inactivated included study. Quantitative IgG antibodies (ADVIA Centaur® IgG, investigated 28 days after first (n= 939) second 771). addition,...
Infectious diseases (ID) trainees should be familiar with duties relevant to consultation practice. In this study we aimed analyze the ID trainee night/weekend shift process in terms of consultant characteristics, types recommendations, and compliance recommendations.All consultations performed by on night at weekends between 10 June August 2004 were recorded prospectively standardized forms. specialists assessed appropriateness recommendations day after each consultation. Recommendations...
Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised patients. Many cases pulmonary, cutaneous, cerebral, paranasal sinus immunocompetent patient were defined literature but disseminated very rare. Here we present an case with extrapulmonary due to Aspergillus niger, totally recovered after effective antifungal treatment voriconazole.
Abstract The purpose of the present investigation was to prepare pH-sensitive hydrogels from photo-crosslinked poly(ethylene glycol) diacrylate (PEG-DA). Rutile titanium dioxide (TiO 2 ) employed modify PEG-DA hydrogels. rutile nanoparticles were prepared by direct oxidation in presence polyethylene glycol (PEG) at high temperature. characterized FT-IR, XRD and SEM. influence experimental conditions, such as pH, type amount photoinitiators on release profiles donepezil hydrochloride (active...
Colistin is used as a salvage therapy for multidrug-resistant and extremely drug-resistant gram-negative bacterial infections. Our aim was to evaluate colistin efficiency toxicity in the treatment of these resistant infections.This retrospective study carried out tertiary care hospital during 2011-2013. Study data were collected from medical records consultations infectious diseases clinic.The group included 158 patients with nosocomial infections 136 (86.1%) them hospitalized ICU....
In this multicenter prospective cohort study, it was aimed to evaluate the bacterial and viral etiology in community-acquired central nervous system infections by standart bacteriological culture multiplex polymerase chain reaction (PCR) methods. Patients hospitalized with between April 2012 February 2014 were enrolled study. Demographic clinical information of patients collected prospectively. Cerebrospinal fluid (CSF) samples examined methods, PCR (Seeplex meningitis-B ACE Detection...
Sorption and pervaporation experiments were carried out for pure ethanol, ethyl acetate their binary mixtures using zeolite 13X-filled poly(dimethylsiloxane) membranes prepared by the solution–casting method. The sorption values increased in proportion with amount of mixtures. excess Gibbs free energies activity coefficients calculated UNIFAC method used simultaneously to determine interaction parameters acetate–ethanol mixture. effects temperature feed concentration on flux selectivity...
syndrome coronavirus-2 (SARS-CoV-2
Each year, approximately 125 million people visit malaria-endemic countries. This study aimed to investigate the clinical characteristics of imported Plasmodium falciparum malaria infections in Türkiye.The included patients diagnosed with P. between 1996 and 2022. A retrospective evaluation was conducted on whole blood samples and/or smears, as well detailed medical histories, manifestations, laboratory findings. total 131 cases were study.Among patients, 121 male. Of these, 101 had traveled...
The aim of the present study is to develop hydroxyapatite modified PEG-DA and PEG-DA/HEMA based hydrogels for release Donepezil HCl potential treatment Alzheimer’s disease. [2,2-Dimethoxy-2-phenyl-acetophenone] (Irgacure 651), 1 Hydroxycyclohexyl phenyl ketone 184) 2-Hydroxy-4'-(2-hydroxyethoxy)-2-methylpropiophenone 2959) were used as photo-initiators in synthesis was modifying hydrogels. Fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM) digital utilized...
Background/aim: Broad-spectrum antibiotics have become available for use only with the approval of infectious disease specialists (IDSs) since 2003 in Turkey. This study aimed to analyze tendencies doctors who are not (non-IDSs) towards restriction antibiotics. Materials and methods: A questionnaire form was prepared, which included a total 22 questions about impact antibiotic (AR) policy, role IDSs restriction, perception this change consumption. The completed by each participating...
Solid organ transplantasyonu (SOT) son dönem yetmezliği olan hastaların yaşam kalitesini ve sağkalım süresini arttıran bir tedavi yöntemidir.Bu hasta gruplarına verilen immünsüpresif tedaviler invazif fungal enfeksiyonların (İFİ) gelişmesine yatkınlık oluşturabilmektedir.SOT alıcılarında İFİ insidansı, transplante edilen organa bağlı olup %5-42 arasında değişmektedir.Transplant yapılan göre değişmekle birlikte en sık izole etken Candida spp.olup bunu Aspergillus spp.takip etmektedir.Gelişen...
: 2-hydroxyl ethyl methacrylate/poly(ethylene glycol) diacrylate (HEMA/PEG-DA) based hydrogels are attractive drug carriers due to their appealing properties such as biodegradability and sustained release. The scope of this study was investigate the swelling release behaviors HEMA/PEG-DA-based filled with low concentrations nanoparticle titanium dioxide (TiO2). Hydrogels have been synthesized successfully by photopolymerization. 2,2-Dimethoxy-2-Phenyl-Acetophenone (Irgacure 651),...
<title>Abstract</title> Objectives To determine the epidemiology and prognosis of sepsis in cancer patients influence on mortality patients. Methods In this multicenter, prospective, observational study, hospitalized without followed up until discharge or a maximum 90 days were included. The incidence follow-up period, risk factors for sepsis, 28-day with 90-day entire group determined. Results During 790 Sepsis developed 72 (9.1%) during follow-up. Older age, hospitalization due to any...
ÖZ Giriş: Achromobacter xylosoxidans (AX) cinsi bakterilere bağlı gelişen