We enrolled consecutive IBS-M patients (n = 25) according to Rome IV criteria. Fecal samples were obtained from all twice (pre-and post-intervention) and high-throughput 16S rRNA sequencing was performed. Six weeks of personalized nutrition diet 14) for group 1 a standard IBS 11) 2 followed. AI-based designed based on optimizing nutritional strategy by an algorithm regarding individual gut microbiome features. The IBS-SSS evaluation pre- post-intervention exhibited significant improvement (p...

INTRODUCTION: Personalized management strategies are pivotal in addressing irritable bowel syndrome (IBS). This multicenter randomized controlled trial focuses on comparing the efficacy of a microbiome-based artificial intelligence-assisted personalized diet (PD) with low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) for IBS management. METHODS: One hundred twenty-one patients participated, 70 assigned to PD group 51 FODMAP group. subtypes, demographics,...

<ns4:p>While the stramenopile <ns4:italic>Blastocystis</ns4:italic>, first discovered in 1911, is considered most prevalent enteric protist humans, its biology remains largely unexplored. Clinical studies have only recently begun investigating role of <ns4:italic>Blastocystis</ns4:italic> gut and relationship with microbiome, whether it plays a pathogenic human animal health. Aiming to gather leading researchers field encourage stimulate cross-disciplinary dialogue while fostering long-term...

İnsanlığın karşı karşıya kaldığı en önemli halk sağlığı sorunlarından biri olan ilaç direnci, antilayşmanyal ajan geliştirmede yeni stratejileri ve yaklaşımları zorunlu kılmaktadır. Dışa atım pompa inhibitörleri (DAPİ) diğer aday ajanlar ile ilgili gelişmeler umut verici olmakla birlikte, mevcut antilayşmanyallerin kullanım sürelerini etkinliklerini artırabilme arayışları da devam etmektedir. Bu çalışmada rezerpin (REZ), berberin (BER) verapamil (VER) olmak üzere üç adet DAPİ'nin...

Leishmania infantum is widely recognized as the primary causative agent of visceral leishmaniasis (VL) in Turkey, while tropica predominantly causes cutaneous (CL). Although L. capable causing VL, such cases remain exceedingly rare. This study aimed to identify genetic factors underlying visceralization potential by comparing isolates from VL and CL patients. Fourteen patients diagnosed with infection, confirmed parasite detection genotyping between 2012 2022, were included: seven CL....

Intestinal protozoan parasites are common causes of infectious diarrhea in children receiving anticancer therapy or undergoing transplantation. Additionally, immunosuppression such patients may exacerbate the symptoms related to these parasitic infections. The aim this study was evaluate prevalence and diagnostic importance infections treated for malignancies transplantation, highlight control intestinal immunosuppressed at a hospital İzmir, Turkey. In total, 82 stool samples from 62 were...

Parasites might cause atypical and severe infections in immunocompromised hosts. The prevalence of diarrhea among common variable immune deficiency (CVID) syndrome patients varies between 20% 94%, which indicates that gastrointestinal system (GIS) complaints could be the second leading morbidity CVID after respiratory tract infections. This study aimed to assess intestinal parasites with GIS diarrhea.In this study, all cases followed up Immunology Allergy Clinic Ege University School...

Background: Currently, medications and behavioral modifications have limited success in the treatment of functional constipation (FC). An individualized diet based on microbiome analysis may improve symptoms FC. In present study, we aimed to investigate impacts modulation chronic constipation. Methods: Between December 2020−December 2021, 50 patients fulfilling Rome IV criteria for were randomized into two groups. The control group received sodium picosulfate plus conventional treatments...

Amaç: Bağışık yetmezliklilerde intestinal parazitik enfeksiyonlar sıktır.Gelişmekte olan ülkelerde HIV (insan immünyetmezlik virüsü) pozitif olgularda enfeksiyonlara bağlı ishal sıklığı %90'ın üzerindedir.Bu çalışmada pozitifliği nedeni ile takip edilen ve gastrointestinal yakınmaları hastalarda bağırsak protozoonlarının varlığının retrospektif olarak incelenmesi amaçlandı.Yöntemler: Çalışmaya 14 kadın (%21,5), 51 erkek (%78,5) olmak üzere toplam 65 hastanın dışkı örneği dahil edildi

The Prevalance of Blastocystosis among Patients with Gastrointestinal and Dermatologic Complaints Effects Blastocystis spp.Density on Symptomatology ÖZ Amaç: diyare, karın ağrısı, gaz hissi gibi non-spesifik belirtilerle ilişkilendirilmektedir.Bu çalışmada, blastocystosisin ürtiker ve gastrointestinal sistem yakınmaları ile olan ilişkisinin araştırılması amaçlanmıştır

Aim and objectives: Trichomonas vaginalis is the most prevalent nonviral sexually transmitted infection globally. The current treatment, 5-nitroimidazole derivatives has raised concerns as a result of drug reliance, allergies, resistance, driving efforts to identify alternative therapies. Vitex species recognized for their pharmacological attributes including anti-inflammatory, antibacterial, antifungal, antimicrobial properties are promising candidates further investigation. Methods: In...

This study examines the risk of malaria, leishmaniasis, and scabies following earthquakes in southeastern Türkiye. The focus is on impact local population Syrian immigrants. Recommendations for prevention include vector control measures such as indoor residual spraying distribution insecticidal nets. Surveillance early detection through rapid diagnostic tests active case finding are important. Public awareness campaigns community engagement crucial promoting protective measures....

Each year, approximately 125 million people visit malaria-endemic countries. This study aimed to investigate the clinical characteristics of imported Plasmodium falciparum malaria infections in Türkiye.The included patients diagnosed with P. between 1996 and 2022. A retrospective evaluation was conducted on whole blood samples and/or smears, as well detailed medical histories, manifestations, laboratory findings. total 131 cases were study.Among patients, 121 male. Of these, 101 had traveled...

The most common types of malaria in the world are Plasmodium vivax and P. falciparum. In countries where both species endemic, falciparum coinfection also occurs. Thus, possibility mixed Turkey should always be considered cases with a traveling history to these countries. Here, we report case vivax/P. infection that was diagnosed as Ethiopia. However, administered treatment inadequate, recurred because miss diagnosis malaria, for which an effective drug hypnozoites not administered. This...

Objective: Visceral Leishmaniasis (VL) is a widespread infectious disease of the reticuloendothelial system which mostly caused by Leishmania infantum and L.donovani. VL zoonotic infection dogs act as main reservoirs while vectors are female Phlebotomus, that to say, sandflies. Although spp. attributed reproduce asexually, genetic exchange between different strains has recently been demonstrated causes interspecific hybrids. We aimed present complete cycle hybrid strain infantum/donovani...