Eu Suk Kim
A5039627231- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Infectious Diseases and Tuberculosis
- Antibiotics Pharmacokinetics and Efficacy
- Nosocomial Infections in ICU
- Viral Infections and Vectors
- Long-Term Effects of COVID-19
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Mosquito-borne diseases and control
- Pneumocystis jirovecii pneumonia detection and treatment
- Infection Control in Healthcare
- Neutropenia and Cancer Infections
- Mycobacterium research and diagnosis
- Viral gastroenteritis research and epidemiology
- Orthopedic Infections and Treatments
- Fungal Infections and Studies
- Bacterial biofilms and quorum sensing
Seoul National University Bundang Hospital
2016-2025
Seoul National University
2016-2025
Seoul National University Hospital
2018-2024
National University College
2017-2023
New Generation University College
2014-2023
Chonnam National University Hospital
2022
Weatherford College
2022
Chung-Ang University Hospital
2022
Namseoul University
2022
Inje University Sanggye Paik Hospital
2020-2022
BackgroundSevere coronavirus disease 2019 (Covid-19) is associated with dysregulated inflammation. The effects of combination treatment baricitinib, a Janus kinase inhibitor, plus remdesivir are not known.MethodsWe conducted double-blind, randomized, placebo-controlled trial evaluating baricitinib in hospitalized adults Covid-19. All the patients received (≤10 days) and either (≤14 or placebo (control). primary outcome was time to recovery. key secondary clinical status at day 15.ResultsA...
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China December 2019.In this retrospective multicenter study, we investigated the clinical course and outcomes of novel disease 2019 (COVID-19) from early cases Republic Korea.Methods: All confirmed by real time polymerase chain reaction were enrolled 1st to 28th patient nationwide.Clinical data collected analyzed for changes severity including laboratory, radiological, virologic...
Abstract We investigated the kinetics of Middle East respiratory syndrome coronavirus (MERS-CoV) neutralizing and spike protein antibody titers over course 1 year in 11 patients who were confirmed by reverse transcription PCR to have been infected during outbreak South Korea 2015. Robust responses detected all survivors had severe disease; remained detectable, albeit with some waning, for <1 year. The duration viral RNA detection (but not load) sputum significantly correlated response...
Clinical Progression and Cytokine Profiles of Middle East Respiratory Syndrome Coronavirus InfectionClinical progression over time cytokine profiles have not been well defined in patients with respiratory syndrome coronavirus (MERS-CoV) infection.We included 17 laboratory-confirmed MERS-CoV during the 2015 outbreak Korea.Clinical laboratory parameters were collected prospectively.Serum chemokine levels serial serum samples measured using enzyme-linked immunosorbent assay.All presented...
Abstract Background Coronavirus disease 2019 (COVID-19) was introduced in Korea early with a large outbreak mid-February. We reviewed the public health interventions used during COVID-19 and describe impact on seasonal influenza activity Korea. Methods National response strategies, daily COVID-19–confirmed cases were pandemic. surveillance data compared between 7 sequential seasons. Characteristics of each season, including rate influenza-like illness (ILI), duration epidemic, date...
Acquired somatic mutations in hematopoietic stem and progenitor cells (clonal hematopoiesis or CH) are associated with advanced age, increased risk of cardiovascular malignant diseases, decreased overall survival. These adverse sequelae may be mediated by altered inflammatory profiles observed patients CH. A pro-inflammatory immunologic profile is also worse outcomes certain infections, including SARS-CoV-2 its disease Covid-19. Whether CH predisposes to severe Covid-19 other infections...
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that was recently identified in China, South Korea and Japan. The objective of the study to evaluate epidemiologic clinical characteristics SFTS Korea.SFTS a reportable Korea. We included all cases reported Centers for Disease Control Prevention (KCDC) from January 2013 December 2015. Clinical information gathered by reviewing medical records, were analyzed using both KCDC surveillance data patient records....
Abstract We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody developed third week illness. Delayed with test were associated more severe disease.
Background: From May to July 2015, the Republic of Korea experienced largest outbreak Middle East respiratory syndrome (MERS) outside Arabian Peninsula.A total 186 patients, including 36 deaths, had been diagnosed with MERS-coronavirus (MERS-CoV) infection as September 30th, 2015.Materials and Methods: We obtained information patients who were confirmed have MERS-CoV infection.MERS-CoV was using real-time reverse-transcriptase polymerase chain reaction assay. Results:The median age 55 years...
We investigated the kinetics of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in 7 asymptomatic persons and 11 patients with pneumonia. The geometric mean titer declined from 219.4 at months to 143.7 5 after infection, indicating a waning antibody response.
Clinical and Epidemiologic Characteristics of Spreaders Middle East Respiratory Syndrome Coronavirus during the 2015 Outbreak in Korea Nosocomial transmission is an important characteristic (MERS-CoV) infection.Risk factors for MERS-CoV healthcare settings are not well defined.During Korean outbreak 2015, 186 patients had laboratory-confirmed infection.Those suspected as a source viral were categorized into spreader groups (super-spreader [n = 5] usualspreader 10]) compared to non-spreader...
Stereotypic antibody clonotypes exist in healthy individuals and may provide protective immunity against viral infections by neutralization. We observed that 13 of 17 patients with COVID-19 had stereotypic variable heavy chain (V
ObjectivesWe hypothesized that immune response may contribute to progression of coronavirus disease-19 (COVID-19) at the second week illness. Therefore, we compared cell-mediated (CMI) responses between severe and mild COVID-19 cases.MethodsWe examined peripheral blood mononuclear cells laboratory-confirmed patients from their first third weeks Severe pneumonia was defined as an oxygen saturation ≤93% room air. Expressions molecules related T-cell activation functions were analyzed by flow...
We retrospectively reviewed medical records to identify the factors that affect results of culture in patients with pyogenic vertebral osteomyelitis. In multivariate analysis, presence paravertebral abscess was associated positive microbiologic culture. Prior antibiotic exposure, especially longer duration, strongly negative results.
Asymptomatic bacteriuria (ABU) is common and often leads to unnecessary antimicrobial use. Reducing antibiotic overuse for ABU therefore an important issue stewardship. We performed this study investigate the appropriateness of management evaluate physicians' knowledge practice regarding ABU.We reviewed all urine cultures ≥10(5) cfu/mL bacteria among inpatients in a 900-bed hospital 2011. Each episode was classified into or urinary tract infection (UTI). defined as positive culture (≥10(5)...
As the coronavirus disease 2019 (COVID-19) has rapidly spread worldwide, there are growing concerns about patients' mental health. We investigated psychological problems in COVID-19 patients assessed with self-reported questionnaires including Patient Health Questionnaire-9, Generalized Anxiety Disorder-7 scale, and Impact of Event Scale-Revised Korean version. Ten who recovered from pneumonia without complications underwent 1 month after discharge. Of them, 10% reported depression...