A5006073568- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Prostate Cancer Treatment and Research
- Lung Cancer Treatments and Mutations
- Radiopharmaceutical Chemistry and Applications
- Neurological disorders and treatments
- Breast Lesions and Carcinomas
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- MRI in cancer diagnosis
- Myasthenia Gravis and Thymoma
- Assisted Reproductive Technology and Twin Pregnancy
- Thyroid Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Glioma Diagnosis and Treatment
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Protease and Inhibitor Mechanisms
- Parkinson's Disease Mechanisms and Treatments
- Neuroblastoma Research and Treatments
- Infectious Diseases and Tuberculosis
- Lymphoma Diagnosis and Treatment
- Blood properties and coagulation
- Renal and Vascular Pathologies
University of California, Los Angeles
2024
Maria Fertility Hospital
2023
Weatherford College
2021
Ewha Womans University
1986-2021
Kyung Hee University
2010-2021
Ewha Womans University Medical Center
2020-2021
Ulsan College
2009-2020
Asan Medical Center
2009-2020
Health Insurance Review and Assessment Service
2018-2020
University of Ulsan
2009-2020
Parkinson disease (PD), progressive supranuclear palsy (PSP), and multiple-system atrophy (MSA) are known to affect dopaminergic neurons of the brain stem striatum with different preferential involvement. Here we investigated differences in striatal subregional dopamine transporter loss PD, PSP, MSA assessed diagnostic value <sup>18</sup>F-fluorinated-<i>N</i>-3-fluoropropyl-2-β-carboxymethoxy-3-β-(4-iodophenyl)nortropane (<sup>18</sup>F-FP-CIT) PET differentiating PSP from PD....
Background: From May to July 2015, the Republic of Korea experienced largest outbreak Middle East respiratory syndrome (MERS) outside Arabian Peninsula.A total 186 patients, including 36 deaths, had been diagnosed with MERS-coronavirus (MERS-CoV) infection as September 30th, 2015.Materials and Methods: We obtained information patients who were confirmed have MERS-CoV infection.MERS-CoV was using real-time reverse-transcriptase polymerase chain reaction assay. Results:The median age 55 years...
Background and PurposezzUnstable carotid atherosclerotic plaques are characterized by cap rupture, leading to thromboembolism stroke.Matrix metalloproteinases (MMPs) have been implicated in the progression of atherosclerosis plaque rupture.The aim this study was assess relationship between expressions MMP-2 MMP-9 instability.MethodszzEighty were collected from 74 patients undergoing endarterectomy.Clinical information obtained each patient, morphology examined at macroscopic microscopic...
The comparative effectiveness of antipsychotic long-acting injections (LAIs) and oral medication is not clear due to various methodological problems.To compare the LAIs antipsychotics in preventing readmission patients with schizophrenia, we performed a within-subject analysis data collected from 75,274 hospitalized schizophrenia over 10-year period (2008-2017). Readmission rates were compared according status (non-medication, alone, LAI medication). Each admission episodes before...
The aim of this study was to explore the ability <sup>18</sup>F-fluoroestradiol (<sup>18</sup>F-FES) PET/CT imaging predict pathologic response neoadjuvant therapy in postmenopausal women with estrogen receptor (ER)–rich breast cancer. <b>Methods:</b> This a prospective, single-center conducted as substudy chemotherapy versus endocrine patients primary cancer (NEOCENT) trial. Patients ER-rich were randomized (NC) or (NET). baseline SUV<sub>max</sub> <sup>18</sup>F-FES measured. assessed by...
To evaluate the usefulness of F-18 fluoro-fluorodeoxygulose positron emission tomography computed (F-18 FDG PET-CT) in detecting clinically defined active disease patients with Takayasu arteritis.F-18 PET-CT was performed 32 arteritis. Disease activity assessed by National Institutes Health (NIH) criteria. In 10 patients, while were taking immunosuppressive drugs. Two nuclear physicians visually degree uptake walls aorta, its major branches and pulmonary artery using a 4-point scale from...
This study evaluated the usefulness of adding single-photon emission computed tomography (SPECT)/computed (CT) (SPECT/CT) to technetium Tc 99m (Tc) hexamethylpropylene amine oxime (HMPAO)-labeled leukocyte imaging for diagnosing infections in hip or knee joint prostheses.The Tc-HMPAO-labeled scans 164 patients (71 with prostheses and 93 prostheses) clinically suspected prosthetic were reviewed retrospectively. Planar images taken 4 6 21 26 hours after injecting labeled leukocytes SPECT/CT...
The pathogenesis of osteonecrosis the femoral head (ONFH) has been implicated in hypofibrinolysis and blood supply interruption. Previous studies have demonstrated that decreased fibrinolytic activity due to elevated plasminogen activator inhibitor-1 (PAI-1) levels correlates with ONFH pathogenesis. -675 4G/5G single nucleotide polymorphism (SNP rs1799889) PAI-1 gene promoter is associated plasma level. We investigated whether rs1799889 two other SNPs (rs2227631, -844 G/A promoter; rs11178,...
The purpose of this study was to determine the 18F-FDG avidity MALT lymphoma and additional utility PET/CT in staging. Pretreatment scans 222 patients with 227 lesions were retrospectively analyzed. noted 28%. proportion lower for gastric lymphomas than non-gastric (9% vs. 60%, p<0.0001) higher mass-forming superficial (82% 2%, p<0.0001). showed presence 23 patients: four six true-positive had avid primary lesions, 15 17 false-positive 18F-FDG-non lesions. differed according location gross...
Sarcopenia- or cachexia-related muscle atrophy is due to imbalanced energy metabolism and oxidative stress-induced dysfunction. Monoterpenes play biological pharmacological reactive oxygen species (ROS) scavenging roles. Hence, we explored the effects of camphene, a bicyclic monoterpene, on skeletal in vitro vivo. We treated L6 myoblast cells with camphene then examined ROS-related stress using Mito TrackerTM Red FM anti-8-oxoguanine antibody staining. To investigate lipid metabolism,...
To explore the added value of histogram analysis apparent diffusion coefficient (ADC) values over magnetic resonance (MR) imaging and fluorine 18 ((18)F) fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed (CT) for detection occult palatine tonsil squamous cell carcinoma (SCC) in patients with cervical nodal metastasis from a cancer an unknown primary site.The institutional review board approved this retrospective study, requirement informed consent was waived. Differences...
<h3>Importance</h3> Current guidelines recommend that women delay pregnancy for 6 to 12 months after the receipt of radioactive iodine treatment (RAIT) following thyroidectomy differentiated thyroid carcinoma. Although concerns exist regarding risks associated with RAIT, no large-scale study, date, has investigated association between RAIT and outcomes. <h3>Objective</h3> To investigate whether was increases in adverse outcomes among South Korean who received cancer evaluate appropriate...
Abstract Nontuberculous mycobacteria (NTM) are important pathogens in humans, and hospital-based studies have shown an increased incidence of NTM infection. However, little is known about the treatment pattern infection with respect to number cases per population South Korea. This study evaluated trends infection, respiratory comorbidities, patterns National claims data from Health Insurance Review Assessment service database for years 2009 2015 were reviewed, codes related comorbidities...
(4S)-4-(3-[18F]Fluoropropyl)-L-glutamic acid (18F-FSPG) is a radiopharmaceutical for PET imaging of system xC- activity, which can be upregulated in prostate cancer. We present data on the first evaluation patients with newly diagnosed or recurrent cancer this radiopharmaceutical.Ten primary and 10 were enrolled prospective multicenter study. After injection 300 MBq 18F-FSPG, three whole-body PET/CT scans obtained. Visual analysis was compared step-section histopathology when available as...
The aim of this study was to evaluate 3′-deoxy-3′-<sup>18</sup>F-fluorothymidine (<sup>18</sup>F-FLT) PET for early prediction the standard anatomic response and survival outcomes in patients with metastatic colorectal cancer (mCRC) receiving leucovorin, 5-fluorouracil (5-FU), oxaliplatin (FOLFOX). <b>Methods:</b> main eligibility criteria included histologically confirmed mCRC, ≥1 extrahepatic measurable lesions, no prior chemotherapy a setting. Chemotherapy consisted leucovorin on day 1,...
Synchronous colorectal cancer liver metastasis (SCLM) remains a clinical challenge, largely because of the limited availability tools that use reliable prognostic indicators to guide treatment. This study assessed ability preoperative (18)F-FDG PET/CT in patients with SCLM who had undergone curative-intent and surgery.All included simultaneous hepatic surgery treat SCLM. Cox regression for survival analysis was undertaken using clinicopathologic variables metabolic parameters (metabolic...
: The microbiome is important in the development and progression of breast cancer. This study investigated effects derived from Klebsiella on endocrine therapy cancer using MCF7 cells. bacterial extracellular vesicles (EVs) that affect were established through experiments focused tamoxifen efficacy.
This study aimed to evaluate the metabolic characteristics of lipiodolized hepatocellular carcinomas (HCCs) and diagnostic accuracy (18)F-FDG PET/CT in assessing viability HCCs.Thirty-six patients (age range, 32-73 y) with 38 HCCs who had undergone transcatheter arterial chemoembolization (TACE) lipiodol before (2-434 d) 55 36-77 57 treatment-naïve not been treated TACE were retrospectively studied. All underwent hepatic lobectomy or transplantation within 1 mo after multiphasic...
Abstract Purpose This study investigated radioactive iodine treatment (RAIT) patterns and the secondary cancer incidence among children young adults receiving RAIT after thyroidectomy for thyroid cancer. Methods population-based cohort used Health Insurance Review Assessment database of South Korea to identify a total 18 617 (0–29 years) who underwent between 2008 2018. We recorded age at surgery, sex, interval from surgery RAIT, doses RAI, number sessions, incidence. Results A 9548 (51.3%)...
Purpose This study was performed to evaluate the usefulness of lymphoscintigraphy in predicting surgical outcomes lymphaticovenous anastomosis (LVA) a patient with extremity lymphedema. Patients and Methods We retrospectively evaluated 133 patients lymphedema who underwent followed by LVA surgery from February 2018 March 2020. Lymphoscintigraphic findings were on following parameters: extent dermal backflow (small/large), lymphatic flow patterns (trunk pattern/proximal-restricted...