A5014189807- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- Antibiotic Resistance in Bacteria
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- COVID-19 and Mental Health
- Influenza Virus Research Studies
- Traditional Chinese Medicine Studies
- Antifungal resistance and susceptibility
- Respiratory viral infections research
- Liver Disease and Transplantation
- Bacterial biofilms and quorum sensing
- Acupuncture Treatment Research Studies
- HIV/AIDS drug development and treatment
- Immune cells in cancer
- Central Venous Catheters and Hemodialysis
- Streptococcal Infections and Treatments
- Brucella: diagnosis, epidemiology, treatment
- Functional Brain Connectivity Studies
- Ultrasound in Clinical Applications
- Biochemical and Structural Characterization
Seoul Medical Center
2019-2024
Yonsei University
2016-2019
Severance Hospital
2015-2018
Korea Institute of Oriental Medicine
2016
Chung-Ang University Hospital
2014-2015
Youngdong University
2015
Yeungnam University
2005
Asan Medical Center
2001
University of Ulsan
2001
National Institute of Agricultural Science and Technology
2001
Remdesivir demonstrated clinical benefit in a placebo-controlled trial patients with severe coronavirus disease 2019 (COVID-19), but its effect moderate is unknown.
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma been expected to increase survival rates as in the case with other emerging viral infections.We describe two cases of COVID-19 treated infusion.Both patients presented pneumonia distress and showed a favorable outcome after use addition systemic corticosteroid.To our knowledge, this is first report therapy for Korea.
Stenotrophomonas maltophilia is a nosocomial pathogen associated with high morbidity and mortality, particularly in immunocompromised or critically ill patients. In this study, we investigated the risk factors for mortality patients S. bacteremia. Retrospectively, medical records from all bacteremia between December 2005 2014 at Severance Hospital, 2000-bed tertiary care hospital Seoul, Korea, were reviewed. Analysis was performed to identify 28-day mortality. total, 142 enrolled study. The...
HIV-associated neurocognitive disorder (HAND) can occur in patients without prior AIDS defining illness and be debilitating. This study aimed to evaluate the difference patterns of intrinsic brain activity between with or HAND for deepening our understanding HAND.We evaluated 24 HIV-infected individuals, 12 previously diagnosed HAND, 11 seronegative individuals. These individuals then underwent repeat NP testing a functional MRI scan. For analysis, seed-based analysis bilateral precuneus...
Recovery mechanisms supporting upper extremity motor recovery following stroke are well established, but cortical mechanism associated with lower is unknown. The aim of this study was to assess reorganization in a hemiparetic patient.Six control subjects and 17 year-old woman left intracerebral hemorrhage due an arterio-venous malformation rupture were evaluated. function the paretic (left) hip knee had recovered slowly extent her being able overcome gravity for 10 months after onset stroke....
The incidence of Proteus mirabilis antimicrobial resistance, especially that mediated by extended-spectrum β-lactamases (ESBLs), has increased. We investigated the impact ESBL production on mortality patients with P. bacteremia in Korea. Patients diagnosed between November 2005 and December 2013 at a 2000-bed tertiary care center South Korea were included this study. Phenotypic molecular analyses performed to assess expression. Characteristics treatment outcomes among ESBL-producing...
Several studies have evaluated the impact of matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) combined with antimicrobial stewardship in patients positive blood cultures; clinical outcomes improved. However, many hospitals, is not available because restricted medical resources. Thus, we investigated evaluation by MALDI-TOF MS on bacteremia and fungemia treated a setting lacking an program (ASP).We designed pre-post quasi experimental study...
Abstract Background Coronavirus disease 2019 (COVID-19) is associated with acute respiratory distress syndrome, and corticosteroids have been considered as possible therapeutic agents for this disease. However, there limited literature on the appropriate timing of corticosteroid administration to obtain best patient outcomes. Methods This was a retrospective cohort study including patients severe COVID-19 who received treatment from March 2 June 30, 2020 in seven tertiary hospitals South...
Spontaneous bacterial peritonitis (SBP) in patients with cirrhosis is typically caused by gram-negative bacteria. However, the number of SBP cases due to gram-positive bacteria steadily increasing. To date, little known about predictive factors involved infections. We performed a retrospective cohort study (>18 years) and -negative who were enrolled from January 2006 December 2013 at Severance Hospital Seoul, Korea where incidences hepatitis B virus associated chronic liver disease,...
Severe sepsis is associated with functional disability among patients surviving an acute phase of infection. Efforts to improve impairment are important. We assessed the effects early exercise rehabilitation on outcomes in severe sepsis. A prospective, single-center, case-control study was conducted between January 2013 and May 2014 at a tertiary care center Korea. Patients septic shock were enrolled randomized receive standard treatment or intervention. Intervention involved targeted...
Multiple comorbidities among HIV-positive individuals may increase the potential for polypharmacy causing drug-to-drug interactions and older with comorbidities, particularly those cognitive impairment, have difficulty in adhering to complex medications. However, effects of age-associated on treatment outcomes combination antiretroviral therapy (cART) are not well known. In this study, we investigated therapeutic cART adults Asian countries.
ABSTRACT. Cryptococcus neoformans infections occur most frequently in immunocompromised patients. Here, we report a case of cryptococcal meningitis previously immunocompetent 78-year-old female patient after treatment COVID-19. Underlying diseases included hypertension, hyperlipidemia, and diabetes. The was critically ill treated with remdesivir, baricitinib, dexamethasone. During hospitalization, her mental state changed, C. detected the cerebrospinal fluid. She died despite receiving...
A novel antiviral agent, remdesivir (RDV), is a promising candidate treatment for coronavirus disease 2019 (COVID-19) in the absence of any proven therapy.This retrospective case series included 10 patients with clinically and laboratory confirmed diagnosis severe COVID-19 pneumonia who had received RDV 5 days (n = 5) or Phase III clinical trial (GS-US-540-5773) conducted by Gilead Sciences. The data these were extracted.One patient 10-day group only because nausea elevated liver...
Acinetobacter baumannii is an aerobic Gram-negative coccobacillus that causes nosocomial pneumonia in patients on mechanical ventilation or previously treated with broad-spectrum antibiotics.Nevertheless, community-acquired (CAP) caused by A. baumannii, especially multi-drug resistant (MDR) strains, rare.We experienced the first case of CAP MDR Korea a 78-year-old man.This shows can cause Korea.
Abstract Backgrounds Remdesivir (RDV) is an antiviral agent approved for the treatment of coronavirus disease 2019 (COVID-19); however, not recommended patients with renal impairment. Due to limitations associated prospective clinical trials, real-world data on safety and efficacy RDV in impairment are necessary. Methods Propensity score-matched (PSM) retrospective analysis was conducted between March 2020 September 2022 COVID-19 eGFR < 30 mL/min four Korean hospitals. The group matched...
Introduction. The purpose of this study was to examine the differences in temperament between So-Yang (SY) and So-Eum (SE) Sasang types using Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scale elucidate biopsychological mechanism underlying typology, a traditional Korean personalized medicine. Methods. 248 university students were categorized into three types, series t-tests conducted, separately for male female participants, difference (BIS), (BAS), BAS-Drive (BAS-D),...
Background This study aimed to determine the parameters for worsening oxygenation in non-severe coronavirus disease 2019 (COVID-19) pneumonia. Methods retrospective cohort included cases of confirmed COVID-19 pneumonia a public hospital South Korea. The group was defined as that with SpO2 ≤94% or received oxygen mechanical ventilation (MV) throughout clinical course versus non-worsening did not experience any respiratory event. Parameters were compared, and extent viral from an initial chest...
Mpox is a viral illness with characteristic skin rash caused by the monkeypox virus. In 2022, spread throughout world, and an epidemic through domestic transmission started in South Korea early 2023. This study aimed to summarize clinical features of patients Korea.
Gastric adenocarcinoma is the most prevalent cancer in South Korea, and Helicobacter pylori (H. pylori) infection also common. This study was performed to examine association between H. gastric cancer, taking into account various other factors. To investigate infection, determined by urease-positive reaction CLO test, a total of 175 paired specimens (175 tumor tissues adjacent tumor) stomach patients 113 control were obtained. The positive rates 78.9% (138/175) among or 41.6% (47/113)...
Brucellosis is a zoonotic infection that usually transmitted from cattle to humans through ingestion of animal milk, direct contact with parts, or inhalation aerosolized particles.In Korea, brucellosis seem be close blood, fetus, urine, and placenta domestic cow has been infected by Brucella abortus, B. arbortus while examining slaughtering cow.Brucella melitensis rare in Korea there have no reported cases originating other countries until now.This report details case complicated infective...
Respiratory viruses (RVs) are considered to be important respiratory pathogens in adult patients, and the multiplex reverse transcription-polymerase chain reaction (RT-PCR) test is used frequently patients with infections. However, clinical data regarding utilization of RT-PCR for RVs lacking.We investigated at Chung-Ang University Hospital Seoul, Korea, between January 2012 April 2013.During study period, was performed 291 patients. The frequency 4.9% rapid influenza antigen detection tests...