A5101988195- Antibiotic Resistance in Bacteria
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- Clostridium difficile and Clostridium perfringens research
- HIV Research and Treatment
- Infection Control and Ventilation
- Myasthenia Gravis and Thymoma
- Infective Endocarditis Diagnosis and Management
- Antifungal resistance and susceptibility
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Pericarditis and Cardiac Tamponade
- Infections and bacterial resistance
- HIV-related health complications and treatments
- Celiac Disease Research and Management
- SARS-CoV-2 detection and testing
- Peripheral Neuropathies and Disorders
- Inflammatory Biomarkers in Disease Prognosis
- Chemical Looping and Thermochemical Processes
Yonsei University
2016-2022
Yonsei University Health System
2021-2022
Severance Hospital
2020-2021
Stenotrophomonas maltophilia is a nosocomial pathogen associated with high morbidity and mortality, particularly in immunocompromised or critically ill patients. In this study, we investigated the risk factors for mortality patients S. bacteremia. Retrospectively, medical records from all bacteremia between December 2005 2014 at Severance Hospital, 2000-bed tertiary care hospital Seoul, Korea, were reviewed. Analysis was performed to identify 28-day mortality. total, 142 enrolled study. The...
Abstract Background Multidrug-resistant organisms (MDROs) such as vancomycin-resistant enterococci (VRE) and carbapenemase-producing Enterobacteriaceae (CPE) are associated with prolonged hospitalisation, increased medical costs, severe infections. Faecal microbiota transplantation (FMT) has emerged an important strategy for decolonisation. This study aimed to evaluate the genetic response of MDROs FMT. Methods A single-centre prospective was conducted on patients infected VRE, CPE, or...
HIV-associated neurocognitive disorder (HAND) can occur in patients without prior AIDS defining illness and be debilitating. This study aimed to evaluate the difference patterns of intrinsic brain activity between with or HAND for deepening our understanding HAND.We evaluated 24 HIV-infected individuals, 12 previously diagnosed HAND, 11 seronegative individuals. These individuals then underwent repeat NP testing a functional MRI scan. For analysis, seed-based analysis bilateral precuneus...
Novel coronavirus (named SARS-CoV-2) can spread widely in confined settings including hospitals, cruise ships, prisons, and places of worship. In particular, a healthcare-associated outbreak could become the epicenter disease (COVID-19). This study aimed to evaluate effects different intervention strategies on hospital within tertiary hospital. A mathematical model was developed for COVID-19 transmission 2500-bed South Korea. The SEIR (susceptible-exposed-infectious-recovered) with...
According to the new definition of septic shock, vasopressor therapy and hyperlactatemia are essential for diagnosis. However, there is controversy regarding cutoff value lactate, prognostic factors in patients with shock hypolactatemia. This study evaluated significance lactate level patients.The retrospective observational cohort enrolled 1043 aged ≥18 years who meet revised shock. Clinical outcomes were compared hypolactatemia.Of 1022 eligible patients, 369 had an arterial ≤2 mmol/L. More...
The incidence of Proteus mirabilis antimicrobial resistance, especially that mediated by extended-spectrum β-lactamases (ESBLs), has increased. We investigated the impact ESBL production on mortality patients with P. bacteremia in Korea. Patients diagnosed between November 2005 and December 2013 at a 2000-bed tertiary care center South Korea were included this study. Phenotypic molecular analyses performed to assess expression. Characteristics treatment outcomes among ESBL-producing...
Abstract Background Coronavirus disease 2019 (COVID-19) is associated with acute respiratory distress syndrome, and corticosteroids have been considered as possible therapeutic agents for this disease. However, there limited literature on the appropriate timing of corticosteroid administration to obtain best patient outcomes. Methods This was a retrospective cohort study including patients severe COVID-19 who received treatment from March 2 June 30, 2020 in seven tertiary hospitals South...
Background: Septic shock remains a leading cause of death, despite advances in critical care management.The Surviving Sepsis Campaign (SSC) has reduced morbidity and mortality.This study evaluated risk factors for mortality patients with septic who received treatment following the SSC bundles.Materials Methods: This retrospective cohort included treatments bundles an urban emergency department between November 2007 2011.Primary secondary endpoints were all-cause 7-and 28-day...
Abstract Objectives We aim to compare the trends of non‐communicable diseases (NCDs) and death among people living with HIV (PLWH) uninfected controls in South Korea. Methods identified PLWH from a nationwide database all Korean citizens enrolled 1 January 2004 31 December 2016. A control cohort was randomly selected for by frequency matching age sex 20:1 ratio. To NCD between groups, adjusted incidence rate ratios outcomes across ages, calendar years times after diagnosis were calculated....
Severe sepsis is associated with functional disability among patients surviving an acute phase of infection. Efforts to improve impairment are important. We assessed the effects early exercise rehabilitation on outcomes in severe sepsis. A prospective, single-center, case-control study was conducted between January 2013 and May 2014 at a tertiary care center Korea. Patients septic shock were enrolled randomized receive standard treatment or intervention. Intervention involved targeted...
In areas where Mycobacterium tuberculosis is endemic, known to be the most common cause of pericarditis. However, difficulty in diagnosis may lead late complications such as constrictive pericarditis and increased mortality. Therefore, identification patients at a high risk for poor prognosis, prompt initiation treatment are important outcome TB The aim this study identify predictive factors unfavorable outcomes HIV-uninfected persons an intermediate burden country. A retrospective review 87...
Brucellosis is a zoonotic infection that usually transmitted from cattle to humans through ingestion of animal milk, direct contact with parts, or inhalation aerosolized particles.In Korea, brucellosis seem be close blood, fetus, urine, and placenta domestic cow has been infected by Brucella abortus, B. arbortus while examining slaughtering cow.Brucella melitensis rare in Korea there have no reported cases originating other countries until now.This report details case complicated infective...
Background: Antepartum, intrapartum, and postpartum preventive measures with antiretroviral drugs, appropriate delivery methods, discouraging breastfeeding significantly decrease the risk of mother-to-child transmission human immunodeficiency virus (HIV) infection.Herein, we investigated pregnancy outcomes in HIV-infected Korean women.Methods: We retrospectively reviewed medical records childbearing-age women between January 2005 June 2017 at four tertiary care hospitals Korea.Results: Among...
Background Brain abscess can be life-threatening and manifest various neurological findings, although the mortality rate has decreased recently. We investigated risk factors for unfavorable outcomes of patients with brain abscess. Methods A retrospective cohort study examined seen from May 2005 to December 2018 in a tertiary care hospital Seoul, South Korea. reviewed medical records clinical therapeutic modalities, prognostic Unfavorable were defined as death, moderate severe disability...
Molecular epidemiology can help clarify the properties and dynamics of HIV-1 transmission networks in both global regional scales. We studied 143 HIV-1-infected individuals recruited from four medical centers three cities South Korea between April 2013 May 2014. env V3 sequence data were generated (337-793 bp) analyzed using a pairwise distance-based clustering approach to infer putative networks. Participants whose viruses ≤2.0% divergent according Tamura-Nei 93 genetic distance defined as...
Gastrectomy is a proxy of malnutrition, which may lead to increased risk for developing pulmonary tuberculosis (TB). Malabsorption in gastrectomy patients could low serum levels rifampicin, be related higher treatment failure. However, there limited information on outcomes TB who have undergone gastrectomy. This study aims determine and adverse effects treated after undergoing gastric cancer. During the period, 112 were active that developed Among them, we selected 15 culture positive at...
Purpose: With changing fungal epidemiology and azole resistance in Aspergillus species, identifying species susceptibility patterns is crucial to the management of aspergillosis mucormycosis.The objectives this study were evaluate performance panfungal polymerase chain reaction (PCR) assays on formalin-fixed paraffin embedded (FFPE) samples identification detection azole-resistance mutations fumigatus cyp51A gene at a South Korean hospital.Materials Methods: A total 75 FFPE specimens with...
In areas where Mycobacterium tuberculosis is endemic, known to be the most common cause of pericarditis. However, difficulty in diagnosis may lead late complications such as constrictive pericarditis and increased mortality. Therefore, identification patients at a high risk for poor prognosis, prompt initiation treatment are important outcome TB The aim this study identify predictive factors unfavorable outcomes HIV-uninfected persons an intermediate burden country. A retrospective review 87...
Moo Hyun Kim, Do Kyun Jung Ho Jin Young Ahn, Su Jeong, Nam Ku, Joon-Sup Yeom, Jun Yong Choi. Korean J healthc assoc Infect Control Prev 2022;27:85-9. https://doi.org/10.14192/kjicp.2022.27.1.85