A5032103760- Sepsis Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Infective Endocarditis Diagnosis and Management
- Antibiotic Resistance in Bacteria
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Mycobacterium research and diagnosis
- Bacterial Identification and Susceptibility Testing
- Antimicrobial Resistance in Staphylococcus
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Antifungal resistance and susceptibility
- Streptococcal Infections and Treatments
- Infections and bacterial resistance
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 and COVID-19 Research
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- HIV, Drug Use, Sexual Risk
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Lymphoma Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Nosocomial Infections in ICU
Yonsei University
2016-2025
University of California, Los Angeles
2023-2025
Severance Hospital
2009-2024
Yonsei University Health System
2019-2024
Seoul Institute
2014-2022
University of California Davis Medical Center
2020
APLA Health
2016
Gangnam Severance Hospital
2014
Christie's
2012
Zero to Three
2012
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma been expected to increase survival rates as in the case with other emerging viral infections.We describe two cases of COVID-19 treated infusion.Both patients presented pneumonia distress and showed a favorable outcome after use addition systemic corticosteroid.To our knowledge, this is first report therapy for Korea.
Sepsis, including severe sepsis and septic shock, is a major cause of morbidity mortality. Albumin C-reactive protein (CRP) are considered as good diagnostic markers for sepsis. Thus, initial CRP albumin levels were combined to ascertain their value an independent predictor 180-day mortality in patients with shock.We conducted retrospective cohort study involving 670 (>18 years old) who admitted the emergency department had received standardized resuscitation algorithm (early goal-directed...
Red blood cell distribution width (RDW) is known to be a predictor of severe morbidity and mortality in some chronic diseases such as congestive heart failure. However, our knowledge, little about RDW patients with Gram-negative bacteremia, major nosocomial cause intra-abdominal infections, urinary tract primary bacteremia. Therefore, we investigated whether an independent Clinical characteristics, laboratory parameters, outcomes 161 bacteremia from November 2010 March 2011 diagnosed at...
Some of the previously reported clinical isolates Elizabethkingia meningoseptica may be later named species We determined accuracy identification (with two matrix-assisted laser desorption ionization-time flight mass spectrometry [MALDI-TOF MS] systems and Vitek 2 GN card), relative prevalence three spp. in specimens, antimicrobial susceptibility identified by 16S rRNA gene sequencing. Specimens for culture were collected from patients a university hospital Seoul, South Korea, between 2009...
A 46-year-old previously healthy female developed flu-like symptoms several days prior to presenting a local hospital. The patient did not note recent travel history, specifically denying China. Sick contact exposure was known. Chest X-ray and computed tomography of the chest showed findings concerning for lobar pneumonia. Subsequent radiology studies worsening lung along with respiratory necessitating intubation ventilation. She transferred university hospital due need an elevated level...
Stenotrophomonas maltophilia is a nosocomial pathogen associated with high morbidity and mortality, particularly in immunocompromised or critically ill patients. In this study, we investigated the risk factors for mortality patients S. bacteremia. Retrospectively, medical records from all bacteremia between December 2005 2014 at Severance Hospital, 2000-bed tertiary care hospital Seoul, Korea, were reviewed. Analysis was performed to identify 28-day mortality. total, 142 enrolled study. The...
Stenotrophomonas maltophilia is an important nosocomial pathogen. This pathogen has intrinsic or acquired resistance to a number of antibiotics classes. Furthermore, infections have been associated with high mortality, mainly in immunocompromised patients. Accordingly, we conducted retrospective cohort study on the clinical data, microbiological characteristics, and outcomes patients S. (SM) bacteremia. A was at two tertiary care referral hospitals Seoul, South Korea. Data were collected...
Purpose: Over the last 30 years, Serratia marcescens (S. marcescens) has emerged as an important pathogen, and a common cause of nosocomial infections.The aim this study was to identify risk factors associated with mortality in patients S. bacteremia.Materials Methods: We performed retrospective cohort 98 who had one or more blood cultures positive for between January 2006 December 2012 tertiary care hospital Seoul, South Korea.Multiple were compared association 28-day all-cause...
Abstract Unfortunately, the options for treating multidrug-resistant (MDR) Acinetobacter baumannii ( A . ) infections are extremely limited. Recently, fosfomycin and minocycline were newly introduced as a treatment option MDR infection. Therefore, we investigated efficacy of combination colistin with minocycline, respectively, therapeutic in pneumonia. We examined carbapenem-resistant isolated from clinical specimens at Severance Hospital, Seoul, Korea. The effect fosfomycin, on bacterial...
Interest in complications and sequelae following Coronavirus disease 2019 (COVID-19) is increasing. Several articles have reported COVID-19-associated autoimmune diseases the association between autoantibodies severity of COVID-19. Thromboembolic are frequent patients with COVID-19, anti-phospholipid antibodies (aPL) frequently detected. We conducted this study to investigate prevalence, clinical significance, persistence anti-nuclear (ANA) aPLs COVID-19.We enrolled diagnosed COVID-19 oxygen...
HIV-associated neurocognitive disorder (HAND) can occur in patients without prior AIDS defining illness and be debilitating. This study aimed to evaluate the difference patterns of intrinsic brain activity between with or HAND for deepening our understanding HAND.We evaluated 24 HIV-infected individuals, 12 previously diagnosed HAND, 11 seronegative individuals. These individuals then underwent repeat NP testing a functional MRI scan. For analysis, seed-based analysis bilateral precuneus...
Only a few observational studies investigated the association between hypochloremia and mortality in critically ill patients, these included small number of septic patients. Also, no study has evaluated effect an increase chloride (Cl-) concentration on mortality. A total 843 Korean patients were divided into three groups based their baseline Cl- level, Cox analyses performed to evaluate 28-day Moreover, change level (ΔCl) from 24, 48, or 72 hour was determined, also conducted relationship...
ObjectivesThe aim of this study was to elucidate patterns severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clearance in the natural course asymptomatic disease 2019 (COVID-19).MethodsConsecutive patients with non-severe COVID-19 were included retrospectively. Asymptomatic a normal body temperature and no evidence pneumonia throughout assigned group. The reverse transcription PCR (RT-PCR) assay repeated every two five days after first follow-up RT-PCR assay. Negative conversion...
The treatment of infective endocarditis (IE) has become more complex with the current myriad healthcare-associated factors and regional differences in causative organisms. We aimed to investigate overall trends, microbiological features, outcomes IE South Korea.A 12-year retrospective cohort study was performed. Poisson regression used estimate time trends incidence mortality rate. Risk for in-hospital were identified multivariable logistic regression, model comparison performed evaluate...
Elizabethkingia species (spp.), which can colonize hospital environments, are emerging nosocomial pathogens presenting high mortality. Due to their intrinsic resistance a broad range of antibiotics, optimal antibiotic dosage has yet be determined against infections caused by spp. This study aimed investigate the risk factors for mortality and assess clinical implications antimicrobial susceptibility patterns. Data from 210 patients affected Elizabethkingia-induced pneumonia bacteremia...
Infections caused by Fusobacterium species are rare; however serious infections with complications or mortality may occur occasionally. We conducted a retrospective study to investigate the clinical features of patients and differences between F . necrophorum , nucleatum varium Additionally, we attempted identify risk factors for -associated mortality. This included all at large tertiary care teaching hospital in South Korea from January 2006 April 2021. Demographic, clinical, laboratory,...
Background: Bacteremia with multidrug-resistant (MDR) Acinetobacter baumannii carbapenem resistance is an important healthcare-associated infection that increases morbidity and mortality in immunocompromised patients. The aim of this study was to assess the annual incidence clinical characteristics such bacteremia identify risk factors for hematopoietic stem cell transplantation (HSCT) recipients. Methods: A retrospective cohort case–control conducted 483 HSCT recipients between January 2005...