A5102950527- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 detection and testing
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 epidemiological studies
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Amoebic Infections and Treatments
- Infections and bacterial resistance
- Vaccine Coverage and Hesitancy
- Diphtheria, Corynebacterium, and Tetanus
- Microscopic Colitis
- Gallbladder and Bile Duct Disorders
- Fungal Biology and Applications
- Antifungal resistance and susceptibility
- Infection Control in Healthcare
Korea University
2017-2023
Korea University Medical Center
2022-2023
Yonsei University
2011-2016
We investigated how differences in age, sex, or vaccine type can affect humoral and cellular immune responses after vaccination with vector (ChAdOx1 nCoV-19), mix-and-match (first, ChAdOx1 nCoV-19, second, BNT162b2), mRNA (BNT162b2 mRNA-1273) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Venous blood was collected from 573 subjects (vector, 396; mix-and-match, 96; mRNA, 81) before the first (
Background/Aims: This study aimed to investigate the clinical characteristics and outcomes of fluorescent antinuclear antibody (FANA)-positive patients admitted for coronavirus disease 2019 (COVID‐19) identify FANA as a prognostic factor mortality.Methods: retrospective was conducted at university-affiliated hospital with 1,048 beds from September 2020 March 2022. The participants were consecutive who required oxygenation through high-flow nasal cannula, non-invasive or mechanical...
Background: Hypervirulent Klebsiella pneumoniae (hvKP) has been the most significant pathogen for liver abscesses in East Asia including Republic of Korea (ROK).Although gastrointestinal colonization K. may cross intestinal barrier to invade liver, characteristics carriage hvKP abscess patients ROK are not well known.Methods: Characteristics isolated from stool samples and aspirate with at a tertiary care hospital between 2017 2018 were evaluated.Results: Out 37 abscess, 11 noted have...
The dynamic nature of coronavirus disease 2019 (COVID-19) pandemic requires us to be efficient and flexible in resource utilization. strategical preparedness response actions the healthcare system are key component contain COVID-19 decrease its case fatality ratio. Depending on epidemiological situation, each medical institution should systematically share responsibility for patient screening, disposition treatment according clinical severity. To overcome fast-paced pandemic, government...
The incidence of Clostridium difficile infection is increasing worldwide, and its severity resulting mortality are also on the rise. Metronidazole oral vancomycin remain treatments choice, but there concerns about treatment failure appearance resistant strains. Furthermore, antibiotic therapy results in recurrence rates at least 20%. Fecal transplantation may be a feasible option for recurrent C. infection; moreover, it an early severe infection. We report case treated with fecal using...
Abstract Background Critically ill patients in intensive care units (ICUs) often acquire opportunistic infections or are colonized by vancomycin-resistant enterococci (VRE), which limits therapeutic options and results high case-fatality rates. In clinical practice, the beneficial effects of universal chlorhexidine gluconate (CHG) bathing on control VRE remain unclear. This study aimed to investigate whether 2% CHG daily reduced acquisition setting a medical ICU (MICU) with endemicity....
Abstract We evaluated the performance of SARS-CoV-2 assays in vaccinated group using receptor-binding domain antibody (RBD Ab assay), neutralizing assay (nAb and interferon-gamma release (IGR assay). also compared based on vaccine type a large population. collected 1,851 samples from individuals with vector, mix-and-match (MM), mRNA vaccines. The RBD was assessed by IgG II Quant (Abbott Laboratories, Sligo, Ireland), (Beckman Coulter, CA, USA), anti-SARS-CoV-2 S (Roche Diagnostics GmbH,...
We evaluated the performance of SARS-CoV-2 assays in vaccinated group using receptor-binding domain antibody (RBD Ab assay), neutralizing assay (nAb and interferon-gamma release (IGR assay). also compared based on vaccine type a large population. collected 1851 samples from individuals with vector, mix-and-match (MM), mRNA vaccines. The RBD was assessed by IgG II Quant (Abbott Laboratories, Sligo, Ireland), (Beckman Coulter, CA, USA), anti-SARS-CoV-2 S (Roche Diagnostics GmbH, Mannheim,...
OBJECTIVESLong-term care facilities (LTCFs) are communal environments for patients with chronic diseases or older adults, making them particularly susceptible to significant harm during infectious disease outbreaks. Nonetheless, LTCFs have historically been subject less stringent infection prevention and control (IPC) mandates. This study aimed assess the current state of develop an IPC system tailored these following coronavirus 2019 (COVID-19) pandemic. METHODSWe conducted online survey...
This study seeks to find the correlation between case fatality rates (CFRs) and third-dose vaccination coverage in 244 counties (si/gun/gu) of South Korea during omicron variant wave. Multivariate regression analyses report that higher were correlated with lower regional CFRs, when controlling for age structure. If rate a county is by 10%, it would have CFR 0.05% (95% confidence interval, 0.03-0.08%). As number cumulative confirmed cases was 16,353,495 as April 20, 2022, 0.03-0.08%...
Since the coronavirus disease 2019 (COVID-19) outbreak, more than 150 million people in over 200 countries have been infected, with 3 dying due to it, as of May 1, 2021. Many researchers are working continuously find effective drug treatments for COVID-19; however, optimal treatment approach remains unclear. In this article, current advances pharmacological patients COVID-19 discussed. Data obtained from recent studies indicate a mortality benefit administration dexamethasone or adjunctive...
Nocardiosis is a rare, but potentially life-threatening condition. It difficult to diagnose, and bacterial culture identification can be time consuming. We investigated the characteristics of nocardiosis suitability treatment approach in Korea.
Abstract Background The aim of this study was to assess whether people living with HIV were at increased risk severe or critical COVID-19, compared HIV-negative individuals COVID-19. Methods This nationwide descriptive epidemiological performed in South Korea between January 2020 and February 2022. Demographic clinical characteristics analyzed using National Health Insurance claims data collected through the Review Assessment service (HIRA). We statistics Cox proportional hazards regression...
Pneumococcal meningitis (PM) is one of invasive pneumococcal disease (IPD) and considered as a medical emergency with notable morbidity mortality. This study was designed to characterize differences in clinical characteristics outcomes, serotypes, antimicrobial susceptibilities between PM bacteremic pneumonia (PBP) adult patients the Republic Korea (ROK) from prospective observational cohort. Adult IPD cases (≥18 years) were prospectively collected 20 hospitals participated surveillance...