A5010777783- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Respiratory viral infections research
- Emergency and Acute Care Studies
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Nosocomial Infections in ICU
- COVID-19 epidemiological studies
- Chronic Disease Management Strategies
- Sepsis Diagnosis and Treatment
- Legionella and Acanthamoeba research
- Tuberculosis Research and Epidemiology
- Vaccine Coverage and Hesitancy
- Intensive Care Unit Cognitive Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Neurological and metabolic disorders
- Travel-related health issues
- Antibiotic Resistance in Bacteria
- Tracheal and airway disorders
- Dental Research and COVID-19
- Neonatal Respiratory Health Research
- Nutrition and Health in Aging
Hospital Pulido Valente
2016-2025
Centro Hospitalar Lisboa Norte
2016-2025
Sociedade Portuguesa de Cardiologia
2007-2025
Intensive Care Foundation
2024
Universidade Nova de Lisboa
2013-2023
Ordem dos Médicos
2023
Hospital de Santa Maria
2013-2022
Hospital de São João
2022
University of Lisbon
2020
Ministry of Health
2014
Lower respiratory tract infections (LRTI) are the most frequent infectious complication in patients admitted to intensive care unit (ICU). We aim report clinical characteristics of ICU-admitted due nosocomial LRTI and describe their microbiology outcomes.A prospective observational study was conducted 13 countries over two continents from 9th May 2016 until 16th August 2019. Characteristics outcomes ventilator-associated pneumonia (VAP), tracheobronchitis (VAT), ICU hospital-acquired...
Objectives This study aimed to estimate the prevalence of diabetes mellitus (DM) in hospitalized patients with community-acquired pneumonia (CAP) and its impact on hospital length stay in-hospital mortality. Research design methods We carried out a retrospective, nationwide register analysis CAP adult admitted Portuguese hospitals between 2009 2012. Anonymous data from 157 291 were extracted National Hospital Discharge Database we performed DM-conditioned stratified by age, sex year...
Ventilator-associated pneumonia (VAP) is a prevailing nosocomial infection in critically ill patients requiring invasive mechanical ventilation (iMV). The impact of VAP profound, adversely affecting patient outcomes and placing significant burden on healthcare resources. This study assessed for the first time contemporary epidemiology Portugal its system clinical outcomes. Additionally, resource consumption (duration iMV, intensive care unit (ICU), hospital length stay (LOS)) empirical...
Limited information is available on pneumococcal colonization among adults. We studied carriage dynamics in healthy adults using high-sensitivity approaches.Eighty-seven (25-50 years old) were followed for 6 months Portugal. Nasopharyngeal, oropharyngeal, and saliva samples obtained monthly; carriers also sampled weekly. Carriage was investigated by quantitative polymerase chain reaction (targeting lytA piaB) culture. Positive serotyped.Approximately 20% of the intermittent carriers; 10%...
Influenza can have a domino effect, triggering severe conditions and leading to hospitalization or even death. Since influenza testing is not routinely performed, statistical modeling techniques are increasingly being used estimate annual hospitalizations deaths associated with influenza, overcome the known underestimation from registers coded influenza-specific diagnosis. The aim of this study was clinical economic burden in Portugal.The comprised ten epidemic seasons (2008/09-2017/18) two...
The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, vaccine coverage rate (VCR) older adults 18 European countries Israel. Published medical literature official documentation on disease participating were reviewed from 2010/11 until 2022/23 seasons. Information framework for monitoring provision ensuring had access to...
Background: Nosocomial lower respiratory tract infections (nLRTIs) are associated with unfavorable clinical outcomes and significant healthcare costs. nLRTIs include hospital-acquired pneumonia (HAP), ventilator-associated (VAP), other ICU-acquired phenotypes. While risk factors for mortality in these critical to guide preventive strategies, it remains unclear whether they vary based on their requirement of invasive mechanical ventilation (IMV) at any point during the hospitalization....
Recent studies in the USA and northern Europe have shown an increase community-acquired pneumonia (CAP). In southern Europe, this has not yet been documented. We carried out a retrospective analysis from encoded information Portuguese database for hospital admissions that included all individuals aged ≥18 years, with primary diagnosis of pneumonia, who were discharged between 2000 2009. excluded patients infected HIV, immunocompromised as result anti-cancer or immunosuppressive treatment,...
The COVID-19 pandemic has caused major damage and disruption to social, economic, health systems (among others). In addition, it posed unprecedented challenges public policy/decision-makers who have been responsible for designing implementing measures mitigate its strong negative impact. Portuguese authorities used decision analysis techniques assess the impact of implemented counties, regions, or across entire country. These tools subject some criticism many stakeholders requested novel...
Abstract Background Despite their higher risk of developing severe disease, little is known about the burden influenza in Portugal children aged < 5 years old. This study aims to cover this gap by estimating clinical and economic children, Portugal, during ten consecutive seasons (2008/09-2017/18). Methods We reviewed hospitalizations old using anonymized administrative data covering all public hospitals discharges mainland Portugal. The hospitalization in-hospital mortality directly...
In 2019, a new virus, SARS-CoV-2, responsible for the COVID-19 disease, was discovered. Asymptomatic and mildly symptomatic patients were forced to quarantine closely monitor their symptoms vital signs, most of time at home. This paper describes e-CoVig, novel mHealth application, developed as an alternative current monitoring paradigm, where are followed up by direct phone contact. The e-CoVig provides set functionalities remote reporting symptoms, other clinical information health services...
The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum lower respiratory tract infections (LRTI), defined specific epidemiological, and microbiological aspects. A European network for ICU-related (ENIRRIs), supported the Respiratory Society, has been recently established, with aim at studying all infective episodes except community-acquired ones. multicentre, observational study is in progress, enrolling more than 1000 fulfilling clinical,...
Current COVID-19 epidemics was declared on December 31, 2019 at the Wuhan city seafood market, rapidly spreading throughout China, and later reaching several countries (mainly South Korea, Japan, Italy Iran) and, since March 1, Portugal. Most of infected patients present with mild symptoms, not requiring hospitalization. Among those admitted to hospital, 6% 10% require admission intensive care unit. These recommendations are aimed support organization services respond COVID-19, providing...
Influenza, an infectious disease of the respiratory system, represents a major burden for public health. This affects all age groups with different prognosis, being life threatening vulnerable individuals. Despite influenza vaccine-preventable disease, control infection needs annual vaccination campaigns and constant improvements. Herein, main challenges in relation to pathogenic agent, available vaccines health impact identified during Light on Vax event, expert meeting organized by...
Background Pneumonia is one of the leading causes mortality and has a high burden in morbidity. In Portugal, 7-valent pneumococcal conjugated vaccine (PCV) was used since 2001 PCV10/13 2009, being last introduced into National Immunization Program 2015. Methods We conducted an ecological study to evaluate impact PCV7 PCV13 on pneumonia (PP) hospitalizations adults aged 65 years or more Portugal. hospital discharge registry data from 1998/99 2015/16 were used, PP hospitalization defined as...
Influenza affects millions of people worldwide each year and can lead to severe complications, hospitalizations, even death, especially among vulnerable populations such as older adults those with chronic medical conditions. Annual vaccination is considered the most effective measure for preventing influenza its complications. Despite widespread availability vaccines, however, coverage rates remain suboptimal in several countries. Based on latest scientific evidence expert opinions patients...