Rok Čivljak

ORCID: 0000-0001-8766-7438
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About
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Research Areas
  • Viral Infections and Vectors
  • Pneumonia and Respiratory Infections
  • COVID-19 Clinical Research Studies
  • Bacterial Infections and Vaccines
  • Infectious Diseases and Tuberculosis
  • Viral Infections and Outbreaks Research
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Influenza Virus Research Studies
  • Hepatitis Viruses Studies and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 epidemiological studies
  • Respiratory viral infections research
  • Vaccine Coverage and Hesitancy
  • Polyomavirus and related diseases
  • Tuberculosis Research and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Hepatitis B Virus Studies
  • HIV/AIDS Research and Interventions
  • Brucella: diagnosis, epidemiology, treatment
  • Nosocomial Infections in ICU
  • Infective Endocarditis Diagnosis and Management
  • HIV, Drug Use, Sexual Risk
  • Vector-borne infectious diseases
  • COVID-19 and Mental Health
  • Hepatitis C virus research

University Hospital for Infectious Diseases "Dr Fran Mihaljevic"
2015-2025

University of Zagreb
2015-2025

University Hospital Centre Zagreb
2004-2022

University of Rijeka
2020-2021

Catholic University of Croatia
2020-2021

Institut za kardiovaskularne bolesti Dedinje
2004

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
2004

Lower respiratory tract infections (LRTI) are the most frequent infectious complication in patients admitted to intensive care unit (ICU). We aim report clinical characteristics of ICU-admitted due nosocomial LRTI and describe their microbiology outcomes.A prospective observational study was conducted 13 countries over two continents from 9th May 2016 until 16th August 2019. Characteristics outcomes ventilator-associated pneumonia (VAP), tracheobronchitis (VAT), ICU hospital-acquired...

10.1007/s00134-023-07210-9 article EN cc-by-nc Intensive Care Medicine 2023-10-01

Background: Most respiratory viruses show pronounced seasonality, but for SARS-CoV-2, this still needs to be documented. Methods: We examined the disease progression of COVID-19 in 6,914 patients admitted hospitals Europe and China. In addition, we evaluated progress symptoms 37,187 individuals reporting into COVID Symptom Study application. Findings: Meta-analysis mortality risk seven European estimated odds ratios per 1-day increase admission date 0.981 (0.973–0.988, p < 0.001)...

10.3389/fmed.2020.607786 article EN cc-by Frontiers in Medicine 2021-01-20

Introduction Clinical case reports enrich medical literature by presenting rare issues. However, that do not adhere to a standard template often lack rigor and limit their usefulness in clinical guidance. Several guidelines for reporting have been structured, while further improvements are still required. The current guideline (CaReL) aims enhance the comprehensiveness of integrating detailed review. Methods In total, 56 researchers were selected based on specific publication criteria...

10.58742/bmj.v2i2.89 article EN cc-by-nc-nd Barw Medical Journal 2024-06-23

The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, vaccine coverage rate (VCR) older adults 18 European countries Israel. Published medical literature official documentation on disease participating were reviewed from 2010/11 until 2022/23 seasons. Information framework for monitoring provision ensuring had access to...

10.1080/17476348.2024.2340470 article EN cc-by-nc-nd Expert Review of Respiratory Medicine 2024-04-02

Background: Nosocomial lower respiratory tract infections (nLRTIs) are associated with unfavorable clinical outcomes and significant healthcare costs. nLRTIs include hospital-acquired pneumonia (HAP), ventilator-associated (VAP), other ICU-acquired phenotypes. While risk factors for mortality in these critical to guide preventive strategies, it remains unclear whether they vary based on their requirement of invasive mechanical ventilation (IMV) at any point during the hospitalization....

10.3390/antibiotics14020127 article EN cc-by Antibiotics 2025-01-26

Coronavirus disease (COVID-19) exhibits a wide spectrum of clinical severity and has been associated with specific biomarkers linked to progression outcomes. This retrospective study analyzed sera from 1222 adult COVID-19 patients hospitalized at the University Hospital for Infectious Diseases in Croatia. We examined association between several laboratory biomarker levels measured patient admission severity, fatal outcomes, viral variants parameters. Deceased surviving severe exhibited...

10.3390/life15040634 article EN cc-by Life 2025-04-10

Introduction: Although vaccines are the safest and most effective means to prevent control infectious diseases, increasing rate of vaccine hesitancy refusal (VHR) has become a worldwide concern. We aimed find opinions parents on vaccinating their children contribute available literature in order support fight against by investigating reasons for VHR global scale.
 Methodology: In this international cross-sectional multicenter study conducted Infectious Diseases International Research...

10.3855/jidc.16085 article EN cc-by The Journal of Infection in Developing Countries 2022-06-30

Healthcare-associated infections are an emerging cause of morbidity and mortality in COVID-19 intensive care units (ICUs) worldwide, especially those caused by multidrug-resistant (MDR) pathogens. The objectives this study were to assess the incidence bloodstream (BSIs) among critically ill patients analyze characteristics healthcare-associated BSIs due MDR Acinetobacter baumannii ICU. A single-center retrospective was conducted at a tertiary hospital during 5-month period. detection...

10.3390/microorganisms11030774 article EN cc-by Microorganisms 2023-03-17

The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum lower respiratory tract infections (LRTI), defined specific epidemiological, and microbiological aspects. A European network for ICU-related (ENIRRIs), supported the Respiratory Society, has been recently established, with aim at studying all infective episodes except community-acquired ones. multicentre, observational study is in progress, enrolling more than 1000 fulfilling clinical,...

10.1183/23120541.00092-2017 article EN cc-by-nc ERJ Open Research 2017-10-01

Tuberculous meningitis (TBM) caused by Mycobacterium tuberculosis resistant to antituberculosis drugs is an increasingly common clinical problem. This study aimed evaluate drug resistance profiles of TBM isolates in adult patients nine European countries involving 32 centers provide insight into the empiric treatment TBM. was cultured from cerebrospinal fluid (CSF) 142 and tested for susceptibility first-line drugs, streptomycin (SM), isoniazid (INH), rifampicin (RIF) ethambutol (EMB)....

10.1186/s12941-015-0107-z article EN cc-by Annals of Clinical Microbiology and Antimicrobials 2015-11-04

To investigate the viral etiology of acute respiratory infection (ARI) in hospitalized adults and elderly patients Croatia, compare prevalence detected viruses, to determine clinical characteristics seasonal occurrence investigated infections.From January 2016 June 2018, a total 182 adult presented with symptoms ARI admitted hospital were tested for 15 viruses by multiplex reverse-transcription polymerase chain reaction. Clinical data collected retrospective analysis patient's chart.A virus...

10.1002/jmv.25437 article EN Journal of Medical Virology 2019-02-26

ABSTRACT Background Most respiratory viruses show pronounced seasonality, but for SARS-CoV-2 this still needs to be documented. Methods We examined the disease progression of COVID-19 in 6,914 patients admitted hospitals Europe and China. In addition, we evaluated progress symptoms 37,187 individuals reporting into COVID Symptom Study application. Findings Meta-analysis mortality risk seven European estimated odds ratios per one day increase admission date 0.981 (0.973-0.988, p<0.001)...

10.1101/2020.07.11.20147157 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2020-07-14

Abstract According to anti-SARS-CoV-2 seroresponse in patients with COVID-19 from Croatia, we emphasised the issue of different serological tests and need for combining diagnostic methods diagnosis. Anti-SARS-CoV-2 IgA IgG ELISA IgM/IgG immunochromatographic assay (ICA) were used testing 60 sera 21 (6 severe, 10 moderate, 5 mild disease). The main clinical, demographic, haemato-biochemical data analysed. most common symptoms cough (95.2%), fever (90.5%), fatigue shortness breath (42.9%)....

10.1007/s10096-020-04019-y article EN cc-by European Journal of Clinical Microbiology & Infectious Diseases 2020-09-04
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