A5030976792- Vector-borne infectious diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- COVID-19 Clinical Research Studies
- Parasites and Host Interactions
- Yersinia bacterium, plague, ectoparasites research
- Leptospirosis research and findings
- Zoonotic diseases and public health
- Diabetes Management and Research
- COVID-19 and healthcare impacts
- Brucella: diagnosis, epidemiology, treatment
- Long-Term Effects of COVID-19
- Fire effects on ecosystems
- Viral Infections and Outbreaks Research
- Chronic Disease Management Strategies
Kazakh National Medical University
2018-2022
Over 60 years ago clinical patterns resembling tick-borne rickettsioses have been described for the first time in Kazakhstan. Since 1995 incidence of cases humans seems to be rising but studies on epidemiological data regarding occurring etiological agents, tick vector species, prevalence and distribution throughout Kazakhstan are still scarce date. The aim study was molecular investigation ticks spotted-fever group rickettsiae endemic Kyzylorda region so far considered as non-endemic Almaty...
The aim of this study was to detect the seroprevalence Crimean-Congo haemorrhagic fever virus (CCHFV) in patients with unknown origin (FUO) endemic (Kyzylorda) and non-endemic (Almaty) oblasts Kazakhstan.Paired serum samples from 802 FUO were collected. Serum investigated by ELISA IgG IgM antibodies against CCHFV. Sera suspected acute infection further RT-PCR viral RNA.IgG detected 12.7% sera both oblasts. Acute shown four Kyzylorda, only one developing severe CCHF. Viral RNA found other...
Abstract Background In the South of Kazakhstan, Almaty Oblastʼ (region) is endemic for tick-borne encephalitis, with 0.16–0.32 cases/100,000 population between 2016–2018. The purpose this study was to determine prevalence and circulating subtypes encephalitis virus (TBEV) in Kyzylorda Oblastʼ. Methods 2015 we investigated 2341 ticks from 7 sampling sites presence TBEV. Ticks were pooled 501 pools isolated RNA tested TBEV by RT-qPCR. For positive samples, E gene amplified, sequenced a...
Abstract Flaviviruses are a family of viruses that cause many diseases in humans. Their similarity the antigenic structure causes cross‐reaction, which complicates precise diagnostic disease causing agents. Tick‐borne encephalitis virus (TBEV), member flavivirus family, is tick‐borne (TBE). Worldwide awareness this raising, however, countries such as Republic Kazakhstan (KZ) there lack serological investigation flaviviruses In our study, we focused on two TBE endemic regions KZ (East Oblast...
Abstract Objective Orthohantaviruses are geographically widely distributed and present various clinical manifestations from mild symptoms to the severe form of haemorrhagic fever with renal syndrome (HFRS) in Eurasia. Official registration HFRS Kazakhstan started year 2000. However, true prevalence human infections by orthohantaviruses within is unknown. The aim this study was investigate seroprevalence orthohantavirus patients unknown origin (FUO) two regions, Almaty Kyzylorda region....
Undifferentiated febrile illness still represents a demanding medical problem all over the world, but primarily in low- and middle-income countries. Scientific clinical investigations related to undifferentiated rickettsial diseases Kazakhstan are lacking. This study reflects investigation of antibodies against spotted fever group (SFG) typhus (TG) rickettsiae patients with southern region (Almaty Kyzylorda oblasts). Paired serum samples were gathered from 13 hospitals these two oblasts...
Background. Rickettsia typh i belongs to the typhus group of rickettsiae and causes endemic typhus. Cases seropositivity R. typhi have been reported in neighbouring China Russia. However, little is known Kazakhstan. The purpose this study was evaluate prevalence IgG antibodies population southern region Methods. A total 253 individuals (142 women, 111 men) aged from 1 71 years were recruited into study. Detection serum against performed by enzyme-linked immunosorbent assay (ELISA). Results....
Objective . To identify clinical and laboratory differences of COVID-19 in patients with hypertension (HTN), as well to factors associated its severe course these patients. Design methods A retrospective analysis case histories 940 was performed. Statistical carried out by the method contingency tables using Pearson's Chi-square test Bonferroni correction, multiple logistic regression ROC-analysis were also applied. Results The group HTN showed a number significant compared without history....
<b>Objective:</b>&nbsp;To investigate the prevalence of diabetes mellitus in comorbidity structures and its effect on clinical course hospitalized COVID-19 patients south region Kazakhstan.<br /> <b>Material methods:</b> A retrospective analysis data from 918 with treated at City Clinical Infectious Diseases Hospital was carried out. Pearson's Chi-square test Student's t-test were conducted.<br <b>Results:</b> In Kazakhstan, occupies second...