A5071531851- HIV-related health complications and treatments
- Antibiotic Use and Resistance
- Diagnosis and treatment of tuberculosis
- Tuberculosis Research and Epidemiology
- HIV Research and Treatment
- Systemic Lupus Erythematosus Research
- Fungal Infections and Studies
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Pharmaceutical Practices and Patient Outcomes
- Antibiotic Resistance in Bacteria
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS drug development and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Neonatal and Maternal Infections
- Atherosclerosis and Cardiovascular Diseases
- Nuclear Structure and Function
- Intraperitoneal and Appendiceal Malignancies
- Cardiovascular Disease and Adiposity
- Enterobacteriaceae and Cronobacter Research
- Kawasaki Disease and Coronary Complications
- Leptospirosis research and findings
- Long-Term Effects of COVID-19
- Dermatological and COVID-19 studies
- Chronic Lymphocytic Leukemia Research
Ovidius University
2015-2023
Clinical Emergency Hospital Bucharest
2023
Chest Diseases Hospital
2021
Spitalul Clinic Judetean Mures
2016
Infections with carbapenem-resistant Enterobacteriaceae are emerging as an important challenge in healthcare settings. Currently, Klebsiella pneumoniae (CRKP) the species of CRE most commonly encountered hospitals. CRKP is resistant to almost all available antimicrobial agents, and infections have been associated high rates morbidity mortality, particularly among persons prolonged hospitalization exposed invasive devices. We report nine patients hospitalized intensive care unit (ICU) severe...
Since the beginning of COVID-19 pandemic, empiric antibiotics (ATBs) have been prescribed on a large scale in both in- and outpatients. We aimed to assess impact antibiotic treatment outcomes hospitalised patients with moderate severe coronavirus disease 2019 (COVID-19).We conducted prospective multicentre cohort study six clinical hospitals, between January 2021 May 2021.We included 553 patients, whom 58% (311/553) were antibiotics, while bacteriological tests performed 57% (178/311) them....
Introduction: Although vaccines are the safest and most effective means to prevent control infectious diseases, increasing rate of vaccine hesitancy refusal (VHR) has become a worldwide concern. We aimed find opinions parents on vaccinating their children contribute available literature in order support fight against by investigating reasons for VHR global scale.
 Methodology: In this international cross-sectional multicenter study conducted Infectious Diseases International Research...
It is well known that during the coronavirus disease 2019 (COVID-19) pandemic, antibiotics were overprescribed. However, less regarding arguments have led to this overuse. Our aim was understand factors associated with in-hospital antibiotic prescription for COVID-19, and rationale behind it. We chose a convergent design mixed-methods study. Quantitative data prospectively obtained from 533 adult patients admitted in six hospitals (services of internal medicine, infectious diseases...
The purpose of our study was to evaluate clinical and pathological characteristics as well treatment outcomes in HIV-infected patients with disseminated tuberculosis from the Regional HIV/AIDS Center Constanţa, Romania, determine associated risk factors.We analyzed adults diagnosed (TB) over past two years, monitored Constanţa.Out a total number 956 patients, 42 had been years (2011-2013) (4.39%) 16 them developed TB (38%). At time diagnosis, we recorded abnormal chest X-rays 8 (50%),...
Infective endocarditis represents a rare complication among patients infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2); it is often nosocomial infection and the symptomatology can be masked by failure symptoms from SARS-CoV-2 bronchopneumonia. Management of forms SARS-COV-2 who also have associated infective very difficult, especially in mono-specialty hospitals (such as infectious diseases hospitals) where access to cardiological investigations limited. The current...
Introduction Many Romanian children were infected nosocomially with human immunodeficiency virus (HIV) in the late 1980s.The Romanian-American Children's Center of Excellence Constanța continues to follow approximately 450 these patients.In 2001, 414 patients initiated on triple therapy including lopinavir/ritonavir.Data from this cohort treated through August 2006 published April 2007 demonstrating that treatment was well tolerated, 337 (81%) remaining after a median duration >4 years.The...
Objective To identify carbapenem-resistant Enterobacteriaceae (CRE) in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) and to determine whether they had different risk factors for the acquisition of CRE than without COVID-19. Methods This retrospective single-centre, case–control study enrolled The demographic, clinical, infection, colonization mortality data were compared between two groups. Results A total 38 COVID-19 26 enrolled. majority...
Emery–Dreifuss muscular dystrophy (EDMD) is a rare genetic disease that affects the musculoskeletal system, including heart, causing rhythm disorders and cardiomyopathy, sometimes requiring an implantable cardioverter-defibrillator (ICD) or heart transplantation due to severe damage. The case described herein concerns 16-year-old girl, with grade II obesity, without other known pathological antecedents cardiac pathology diagnosis given annual history of cardiological investigations. She was...
People living with HIV infection are at high risk for cardiovascular events due to inflammation and atherosclerosis. Also, some antiretroviral therapies may contribute the of complications. Immune status is highly dependent on level lymphocyte T helper CD4+. There data suggesting that immune CD4+ cell count be involved in development complications these patients. Our study longitudinal retrospective included a total number 50 patients associated acute coronary syndrome, divided into two...
The pathophysiology of accelerated atherosclerosis in people living with Human Immunofediciency virus (HIV) is complex. Coronary artery disease (CAD) has become an important cause mortality these patients. They often have atypical symptoms, leading to frequently missed diagnoses. We report a case 51-year-old male undergoing antiretroviral therapy who was admitted for acute coronary syndrome. He had severe that involved difficult management.
Background Clostridium difficile is currently considered a significant cause of nosocomial infection and associated with increasing morbidity mortality. The probability colonization hospitalized patients increases the length their hospital stay depends on local epidemiologic situation. study aimed to evaluate epidemiological, clinical treatment features colitis (CDC), relapse risk factors in Infectious Diseases Clinic Gastroenterology Clinic.
Thrombocytopenia is common in SARS-COV-2 infection, and about a quarter of cases have moderate thrombocytopenia. Severe thrombocytopenia less associated with severe forms COVID-19. The pathogenesis this appears to be complex, the immune mechanism being incriminated. Immune thrombocytopenic purpura (ITP) one complications COVID-19 has an increased risk mucosal or cutaneous bleeding.We present case 72-year-old woman admitted hospital who developed 13 days after onset COVID symptoms. Nine...
Kaposi`s Sarcoma (KS) is the most common malignancy in HIV-infected patients. It`s induced by an infection with Human Herpesvirus 8. AIDS-related Kaposi sarcoma tends to have aggressive clinical course because it may involve all skin, membranes, lymph nodes, stomach, gut, lung or liver. A 32-year-old patient was diagnosed 2009 HIV and disseminated KS. Purple macules nodules were on trunk, limbs lingual mucosa. He a late presenter CD4-T cell count 30 cells/µL 108,000 copies/mL HIV-RNA....
Abstract In the past years there have been numerous discoveries regarding treatment of patients with HIV. If at first doctors watched as live longer, now we want these to better regimens potent, safe, individualized and without side effects. HAART has revolutionized “the world HIV” caused a significant reduction in mortality, morbidity associated HIV-related opportunistic infections. However, effects HAART, metabolic toxicity (such abnormal fat distribution, lipid glucose metabolism, bone...
Perinatal infections include pregnancy associated infections, fetus infection during labor, and other types of including the early postnatal late ones that appeared in range one month after birth. They represent a constant threat to health conceptus, newborn. Therefore their diagnosis is fundamental terms establishing fair treatment maternal for prophylaxis product conception fetal illness neonatal infections. Starting from current practice realities, authors show need infectious disease...
The incidence of Mycobacterium avium Complex (MAC) Disease in HIV-infected individuals has significantly decreased recent years due to the introduction Highly Active Antiretroviral Therapy (HAART) and initiation Clarithromycin prophylaxis. We present case a patient with advanced AIDS, generalized lymphadenopathy digestive symptoms, diagnosed disseminated MAC, diagnosis which was based on results obtained from axillary lymph node intestinal biopsies. Considering time MAC relation...
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Abstract Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterised by a varied clinical picture. In some cases the evolution may be unfavourable, progressing to pneumonia and distress syndrome. Clinical case: A 70-years-old woman, with multiple comorbidities, was admitted for low-grade fever, dry cough loss of appetite, symptoms that started 4 days prior hospitalisation. She initially diagnosed mild disease 2019 (COVID-19). On 18th day illness,...