- Antibiotic Resistance in Bacteria
- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Urinary Tract Infections Management
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Bacterial Identification and Susceptibility Testing
- Clostridium difficile and Clostridium perfringens research
- Pneumonia and Respiratory Infections
- Salmonella and Campylobacter epidemiology
- Streptococcal Infections and Treatments
- Probiotics and Fermented Foods
- Fungal Infections and Studies
- Mycobacterium research and diagnosis
- Gut microbiota and health
- Actinomycetales infections and treatment
- Infective Endocarditis Diagnosis and Management
- Infectious Diseases and Mycology
- Infections and bacterial resistance
- Bacterial biofilms and quorum sensing
- Nosocomial Infections in ICU
- Viral gastroenteritis research and epidemiology
- Pediatric Urology and Nephrology Studies
- Nail Diseases and Treatments
- Microscopic Colitis
University Hospital of Heraklion
2016-2025
University of Crete
2001-2019
Sismanoglio General Hospital
2019
Hellenic Air Force
2019
Science and Technology Park of Crete
2014
Stenotrophomonas maltophilia is acquiring increasing importance as a nosocomial pathogen.We retrospectively studied the characteristics and outcome of patients with any type S. infection at University Hospital Heraklion, Crete, Greece, between 1/2005-12/2010. antimicrobial susceptibility was tested agar dilution method. Prognostic factors for all-cause in-hospital mortality were assessed multivariate logistic regression.Sixty-eight (median age: 70.5 years; 64.7% males) infection, not related...
Abstract Resistance of Acinetobacter baumannii to multiple clinically important antimicrobials has increased very high rates in Greece, rendering most them obsolete. The aim this study was determine the molecular epidemiology and susceptibilities A. isolates collected from different hospitals across Greece. Single-patient strains isolated blood cultures ( n = 271), 19 hospitals, a 6-month period (November 2020–April 2021) were subjected minimum inhibitory concentration determination testing...
The ESCPM group (Enterobacter species including Klebsiella aerogenes - formerly Enterobacter aerogenes, Serratia species, Citrobacter freundii complex, Providencia and Morganella morganii) has not yet been incorporated into systematic surveillance programs. We conducted a multicentre retrospective observational study analysing all strains isolated from blood cultures in 27 European hospitals over 3-year period (2020-2022). Diagnostic approach, epidemiology, antimicrobial susceptibility were...
This study evaluated the effects of broad-spectrum antibiotics on gastrointestinal (G.I.) yeast flora humans and correlated findings with those obtained from a mouse model G.I. colonization by Candida albicans. We prospectively studied 46 adult cancer patients who received one five (ceftriaxone, ceftazidime, ticarcillin-clavulanic acid, imipenem-cilastatin, aztreonam) as therapy for infections. Quantitative examination stools was conducted at baseline, end antibiotic treatment, 1 week after...
We evaluated the in vitro activity of fosfomycin against urinary isolates a region Greece that exhibits considerable antimicrobial resistance by evaluating retrospectively relevant susceptibility data retrieved from microbiological library University Hospital Heraklion, Crete, Greece. examined 578 isolates. In total, 516 (89.2%) were susceptible to fosfomycin; 415 gram negative, and 101 positive. Fosfomycin appears exhibit good levels
Background and aim A multicentre nationwide surveillance study was conducted in Greek hospitals to evaluate epidemiology of carbapenemase-producing Klebsiella pneumoniae clinical isolates, their susceptibilities last-line antibiotics. Methods: Minimum inhibitory concentrations (MICs) were evaluated by Etest, colistin MICs also broth microdilution SensiTest (now known as ComASP) Colistin. Carbapenemase genes detected PCR. Clonal relatedness assessed PFGE. Isolates prospectively collected...
Introduction Clinical case reports enrich medical literature by presenting rare issues. However, that do not adhere to a standard template often lack rigor and limit their usefulness in clinical guidance. Several guidelines for reporting have been structured, while further improvements are still required. The current guideline (CaReL) aims enhance the comprehensiveness of integrating detailed review. Methods In total, 56 researchers were selected based on specific publication criteria...
Onychomycosis is a chronic fungal nail infection caused by dermatophytes, yeasts or non-dermatophyte moulds (NDMs). It occurs worldwide and accounts for about 50% of all disorders. The incidence the disease prevalence pathogens involved vary in different geographical areas change with time. This study was undertaken to determine epidemiology onychomycosis Crete, Greece during 12-year period. Mycologic investigation (direct microscopy cultures) performed samples taken from 3317 patients...
Vulvovaginal candidiasis (VVC) is a common infection of the genital tract affecting millions women worldwide. Data on epidemiological trends VVC in Greece are scarce. This study was undertaken to evaluate prevalence among symptomatic Crete, Greece, identify Candida species involved and determine their susceptibility antifungals. Over 6-year period (2012-2017), 10 256 with vaginitis were evaluated. Isolation yeasts performed Sabouraud dextrose agar chloramphenicol, isolates identified using...
To investigate the extraintestinal manifestations of non-typhoidal Salmonellae (NTS) infection in immunocompetent infants and children.The study took place at University General Hospital Heraklion, Crete. Over a 10-year period from 1993-2002 we studied 1087 patients, whom 443 were children less than 14 years old, with culture-proven diagnosis NTS infection. Stool blood cultures routinely obtained patients presenting fever diarrhea. The cases invasive otherwise well children, including...
Primary biliary cirrhosis (PBC), a disease of probable autoimmune etiology that affects the small intrahepatic bile ducts mainly middle-aged women is commonly associated with pruritus, xanthomatous lesions, and melanosis. We conducted prospective study to systematically describe skin disorders group PBC patients.A evaluation analysis dermatological manifestations including oral genital lesions was carried out, in 49 patients (45 females 4 males). Median age 63 yr (range 35-87 yr). They were...
OBJECTIVES: To study potential differences in the clinical and microbiological features of hospitalized elderly patients with acute pyelonephritis without diabetes mellitus. DESIGN: Retrospective review medical records. SETTING: University hospital. PARTICIPANTS: Eighty‐eight aged 65 older mellitus (DM) (57 female; 64.8%) 118 controls DM (75 63.6%), matched for age sex, between January 1997 December 2005. MEASUREMENTS: Medical records were reviewed demographic, clinical, characteristics....
Pseudomonas aeruginosa is an unusual uropathogen that mostly responsible for nosocomial or catheter associated urinary tract infections in adults. Data about P. children are scarce. We investigated a well-defined area.Clinical, laboratory and radiological characteristics of all with were compared to those gender matched community acquired Escherichia coli during 12-year period.A total 35 43 infection episodes representing 6.7% cases the study period 70 E. infections. Children more often...
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, distribution of pathogenic species and predominating anatomical sites infection vary with geographical location change over time. The aim this study was to determine epidemiological aetiological factors dermatophytoses in Crete, Greece last 5-year period (2011-2015) their incidence relation gender age patients. We compared our findings those previously reported from same area other parts world. A...