A5078276132- Antibiotic Resistance in Bacteria
- Clostridium difficile and Clostridium perfringens research
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Microscopic Colitis
- Antimicrobial Resistance in Staphylococcus
- Bacterial Infections and Vaccines
- Gut microbiota and health
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Orthopedic Infections and Treatments
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Infective Endocarditis Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Influenza Virus Research Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Enterobacteriaceae and Cronobacter Research
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- Hepatitis Viruses Studies and Epidemiology
- Gastrointestinal motility and disorders
Microbiologie de l’alimentation au service de la santé
2018-2025
Université Paris-Saclay
2015-2025
AgroParisTech
2020-2025
Hôpital Paris Saint-Joseph
2015-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2022
Université Paris-Sud
2014-2021
European Society of Clinical Microbiology and Infectious Diseases
2021
Hôpital Saint Joseph
2019-2020
Hôpital Saint-Louis
2020
Assistance Publique – Hôpitaux de Paris
2020
The ESCPM group (Enterobacter species including Klebsiella aerogenes - formerly Enterobacter aerogenes, Serratia species, Citrobacter freundii complex, Providencia and Morganella morganii) has not yet been incorporated into systematic surveillance programs. We conducted a multicentre retrospective observational study analysing all strains isolated from blood cultures in 27 European hospitals over 3-year period (2020-2022). Diagnostic approach, epidemiology, antimicrobial susceptibility were...
We aimed to describe the clinical presentation, treatment, outcome and report on factors associated with mortality over a 90-day period in Clostridioides difficile infection (CDI). Descriptive, univariate, multivariate regression analyses were performed data collected retrospective case-control study conducted nine hospitals from seven European countries. A total of 624 patients included, which 415 deceased (cases) 209 still alive 90 days after CDI diagnosis (controls). The most common...
In the context of increasing antimicrobial resistance in Enterobacterales, management these UTIs has become challenging. We retrospectively assess prevalence Enterobacterales isolates recovered from urinary tract samples France, between 1 September 2017, to 31 August 2018. Twenty-six French clinical laboratories provided susceptibility 134,162 17 antimicrobials. The most frequent species were E. coli (72.0%), Klebsiella pneumoniae (9.7%), Proteus mirabilis (5.8%), and Enterobacter cloacae...
Despite being implicated in a wide spectrum of community- and healthcare-acquired infections, anaerobes have not yet been incorporated into systematic surveillance programs Europe. We conducted multicentre retrospective observational study analysing all anaerobic strains isolated from blood cultures 44 European Hospital Centres over 4-year period (2020-2023). Diagnostic approach, epidemiology, antimicrobial susceptibility according to EUCAST v. 15.0 were investigated. Our included 14,527...
Non-typable Haemophilus influenzae (NT-Hi) infection is frequently associated with acute otitis media (AOM) treatment failure, recurrence or chronic media. Persistence of otopathogens in a biofilm-structured community was implicated these situations. Here, we compared biofilm production by H. strains obtained culture middle ear fluid (MEF) from children AOM failure and isolated nasopharyngeal (NP) samples healthy those (first episode recurrence). We aimed to evaluate an association clinical...
The immunogenicity of bacterial flagellin has been reported in different studies. By its close interaction with the immune system, represents an interesting adjuvant and vaccine candidate. Salmonella Typhimurium already tested as to stimulate mucosal immunity. Here, we assessed ability Clostridium difficile FliC act a adjuvant, first combined ovalbumin antigen second C. surface protein, precursor S-layer proteins SlpA. Using antigen, compared gut adjuvanticity cholera toxin. Two routes...
Bloodstream infections (BSI) can potentially be life-threatening and are associated with a high crude mortality, moreover an inappropriate first-line antibiotic therapy. Bacterial resistance is more frequently observed. New strategies of BSI management urgently needed.During 18-months period, we prospectively evaluated the clinical impact rapid bacterial identification by MALDI-TOF MS technology combined antimicrobial stewardship team (AST) intervention. Furthermore, during 8-months this...
Abstract Background In a previous study, we demonstrated that rapid antibiotic susceptibility tests (ASTs) can be performed directly on blood culture samples tested Mueller–Hinton Rapid agar (MHR-SIR) with time delay of 6–8 h. Objectives Using this disc diffusion method, analysed the clinical impact associated reporting results in our hospital setting. Methods All patients bloodstream infections (BSIs) related to Enterobacteriaceae or Staphylococcus aureus were prospectively included study....