A5089452702- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Nail Diseases and Treatments
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Actinomycetales infections and treatment
- Streptococcal Infections and Treatments
- Bacterial biofilms and quorum sensing
- Pneumocystis jirovecii pneumonia detection and treatment
- Fungal Infections and Studies
- Bacterial Infections and Vaccines
- Enterobacteriaceae and Cronobacter Research
- Infections and bacterial resistance
- Plant Pathogens and Fungal Diseases
- Reproductive tract infections research
- Urinary Tract Infections Management
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Metabolism and Applications
- Medical Imaging and Pathology Studies
- Chemotherapy-related skin toxicity
- Diverticular Disease and Complications
Agios Pavlos General Hospital
2024-2025
University Hospital of Heraklion
2023-2024
University of Crete
2016-2024
Abstract Resistance of Acinetobacter baumannii to multiple clinically important antimicrobials has increased very high rates in Greece, rendering most them obsolete. The aim this study was determine the molecular epidemiology and susceptibilities A. isolates collected from different hospitals across Greece. Single-patient strains isolated blood cultures ( n = 271), 19 hospitals, a 6-month period (November 2020–April 2021) were subjected minimum inhibitory concentration determination testing...
The ESCPM group (Enterobacter species including Klebsiella aerogenes - formerly Enterobacter aerogenes, Serratia species, Citrobacter freundii complex, Providencia and Morganella morganii) has not yet been incorporated into systematic surveillance programs. We conducted a multicentre retrospective observational study analysing all strains isolated from blood cultures in 27 European hospitals over 3-year period (2020-2022). Diagnostic approach, epidemiology, antimicrobial susceptibility were...
Onychomycosis is a chronic fungal nail infection caused by dermatophytes, yeasts or non-dermatophyte moulds (NDMs). It occurs worldwide and accounts for about 50% of all disorders. The incidence the disease prevalence pathogens involved vary in different geographical areas change with time. This study was undertaken to determine epidemiology onychomycosis Crete, Greece during 12-year period. Mycologic investigation (direct microscopy cultures) performed samples taken from 3317 patients...
Vulvovaginal candidiasis (VVC) is a common infection of the genital tract affecting millions women worldwide. Data on epidemiological trends VVC in Greece are scarce. This study was undertaken to evaluate prevalence among symptomatic Crete, Greece, identify Candida species involved and determine their susceptibility antifungals. Over 6-year period (2012-2017), 10 256 with vaginitis were evaluated. Isolation yeasts performed Sabouraud dextrose agar chloramphenicol, isolates identified using...
Background/Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) poses significant treatment challenges, particularly in community settings. Limited data are available on S. aureus-associated infected dermatoses (ID) outpatient dermatology clinics. This study examines the clinical characteristics, microbiological profiles, resistance patterns, and outcomes of caused by aureus. Methods: Between January 2023 2025, consecutive patients with confirmed SD were recruited a clinic...
Despite being implicated in a wide spectrum of community- and healthcare-acquired infections, anaerobes have not yet been incorporated into systematic surveillance programs Europe. We conducted multicentre retrospective observational study analysing all anaerobic strains isolated from blood cultures 44 European Hospital Centres over 4-year period (2020-2023). Diagnostic approach, epidemiology, antimicrobial susceptibility according to EUCAST v. 15.0 were investigated. Our included 14,527...
Background: Acinetobacter baumannii has emerged as a major cause of nosocomial outbreaks.It is particularly associated with pneumonia and bloodstream infections in immunocompromised debilitated patients serious underlying pathologies.Over the last two decades, remarkable rise rates multidrug resistance to most antimicrobial agents that are active against A. been noted worldwide.We evaluated changes over 5-year period (2010-2014) strains isolated from hospitalized tertiary Greek...
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, distribution of pathogenic species and predominating anatomical sites infection vary with geographical location change over time. The aim this study was to determine epidemiological aetiological factors dermatophytoses in Crete, Greece last 5-year period (2011-2015) their incidence relation gender age patients. We compared our findings those previously reported from same area other parts world. A...
S. aureus is a pathogenic bacterium that causesinfections. Its virulence due to surface components, proteins, genes, SCCmec, pvl, agr, and SEs, which are low molecular weight superantigens. SEs usually encoded by mobile genetic elements, horizontal gene transfer accounts for their widespread presence in aureus. This study analyzed the prevalence of MRSA MSSA strains two hospitals Greece between 2020–2022 susceptibility antibiotics. Specimens collected were tested using VITEK 2 system PCR...
Klebsiella pneumoniae is one of the most prevalent bacteria causing urinary tract infections (UTIs). Its increasing resistance to a wide array antibiotics limits available treatment options. This study investigated characteristics and trends antimicrobial in K. isolated from UTIs Crete, Greece, during 2017 2022. Among 11,946 Enterobacteriaceae urine specimens, total 1,771 isolates were identified (14.8%), with an isolation frequency secondary Escherichia coli (66.3%). increased over years,...
Background/Objectives: Antibiotic (AB) therapy is the first step in managing hidradenitis suppurativa (HS). Knowledge of local patterns antimicrobial resistance paramount for appropriate selection antimicrobials. This study aimed to assess occurrence antibiotic patients with HS. Methods: A cross-sectional was conducted on 103 HS seen at Dermatology Department University Hospital Heraklion, Crete, Greece, from January 2019 December 2023, who were not any antibiotics last three months....
This study provides a comparative analysis of 243 Methicillin-resistant Staphylococcus aureus (MRSA) isolated strains from Greece and Romania, focusing on their epidemiology antibiotic resistance patterns. Laboratory procedures included phenotypic automated identification methods, susceptibility testing, DNA isolation, PCR for detecting genes (MecA, SCCmec). Our results show significant regional differences. In both regions, males have higher MRSA infection rates than females, but the...
Skin and soft tissue infections (SSTIs) are associated with significant morbidity healthcare costs, especially when caused by methicillin-resistant Staphylococcus aureus (MRSA). Vancomycin is a preferred antimicrobial therapy for the management of complicated SSTIs (cSSTIs) MRSA, linezolid daptomycin regarded as alternative therapeutic options. Due to increased rates resistance in several new antibiotics activity against MRSA have been recently introduced clinical practice, including...
Background: Pneumococcal disease is a major cause of morbidity and mortality worldwide, especially in patients with comorbidities advanced age.This study evaluated trends epidemiology adult pneumococcal Crete, Greece, by identifying serotype distribution antimicrobial resistance consecutive Streptococcus pneumoniae strains isolated from adults during an 8-year time period (2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016) the indirect effect infant higher-valent conjugate vaccines 10-valent...
Pneumococcal disease is still considered a global problem. With the introduction of pneumococcal conjugate vaccines (PCVs) serotype epidemiology changed, but antimicrobial resistance persists constituting serious The current study aimed to determine distribution and susceptibility recent
Elizabethkingia anophelis is an opportunistic pathogen causing lifethreatening infections in humans, particularly immunocompromised patients, neonates and elderly. Infections caused by this species are exceptionally challenging to treat due its multiresistance antimicrobials. We report a case of central line-associated bloodstream infection E. 2.5-year-old girl with acute lymphoblastic leukemia successfully treated combination piperacillin/tazobactam amikacin. The literature was also...
is a coagulase-negative staphylococcus (CoNS) commonly found on human skin. Unlike other CoNS,
Infections by carbapenem-resistant Klebsiella pneumoniae (CRKP) remain one of the greatest healthcare threats associated with significant morbidity and mortality. New antimicrobials were recently developed to address this threat. We assessed epidemiology carbapenemase-producing K. (CPKP) isolates recovered in a Greek university hospital during 2021, their susceptibilities old newer antimicrobials. Minimum inhibitory concentrations (MICs) determined MIC Test Strip method, except for...
Mycoplasma hominis and Ureaplasma species are opportunistic pathogens associated with urogenital infections, complications during pregnancy postpartum infections. Appropriate empirical antimicrobial treatment is necessary to achieve an optimal therapeutic outcome. This study evaluated the prevalence susceptibility of spp. isolated from 1,008 endocervical samples outpatients in Crete, Greece, a five-year period (2012–2016), using commercially available Mycoview kit (Zeakon diagnostics,...