Achilleas Gikas
A5069734398- Vector-borne infectious diseases
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Viral Infections and Vectors
- Nosocomial Infections in ICU
- Mosquito-borne diseases and control
- Bacterial Identification and Susceptibility Testing
- Antibiotics Pharmacokinetics and Efficacy
- Infection Control in Healthcare
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Urinary Tract Infections Management
- Leptospirosis research and findings
- Vector-Borne Animal Diseases
- Food Safety and Hygiene
- Infective Endocarditis Diagnosis and Management
- Emergency and Acute Care Studies
- Microscopic Colitis
- Bartonella species infections research
- Surgical site infection prevention
- Central Venous Catheters and Hemodialysis
- Bacterial Infections and Vaccines
- Cardiac, Anesthesia and Surgical Outcomes
- Gut microbiota and health
University Hospital of Heraklion
2014-2023
University of Crete
2012-2023
European University Cyprus
2017
Centers for Disease Control and Prevention
2013
Association for Regional Development and Mental Health
2011
Society for Healthcare Epidemiology of America
2008
Harokopio University of Athens
2008
Chania General Hospital ”St. George”
2004
RMIT University
1995
The General Hospital of Heraklion "Venizeleio-Pananio"
1995
Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed estimate the burden of infections caused by public concern in countries EU European Economic Area (EEA) 2015, measured number cases, deaths, disability-adjusted life-years (DALYs).We estimated incidence with 16 antibiotic resistance-bacterium combinations from Antimicrobial Resistance Surveillance Network...
BackgroundPneumonia and bloodstream infections (BSI) due to extensively drug-resistant (XDR) Acinetobacter baumannii, XDR Pseudomonas aeruginosa, carbapenem-resistant Enterobacterales (CRE) are associated with high mortality rates, therapeutic options remain limited. This trial assessed whether combination therapy colistin meropenem was superior monotherapy for the treatment of these infections.MethodsThe OVERCOME (Colistin Monotherapy versus Combination Therapy) an international,...
To report the results of a surveillance study on surgical site infections (SSIs) conducted by International Nosocomial Infection Control Consortium (INICC). Cohort prospective multinational multicenter study. Eighty-two hospitals 66 cities in 30 countries (Argentina, Brazil, Colombia, Cuba, Dominican Republic, Egypt, Greece, India, Kosovo, Lebanon, Lithuania, Macedonia, Malaysia, Mexico, Morocco, Pakistan, Panama, Peru, Philippines, Poland, Salvador, Saudi Arabia, Serbia, Singapore,...
Antibiotic-induced modulation of the intestinal microbiota can lead to Clostridioides difficile infection (CDI), which is associated with considerable morbidity, mortality, and healthcare-costs globally. Therefore, identification markers predictive CDI could substantially contribute guiding therapy decreasing burden. Here, we analyze hospitalized patients at increased risk in a prospective, 90-day cohort-study before after antibiotic treatment diarrhea onset. We show that developing already...
This study evaluated the effects of broad-spectrum antibiotics on gastrointestinal (G.I.) yeast flora humans and correlated findings with those obtained from a mouse model G.I. colonization by Candida albicans. We prospectively studied 46 adult cancer patients who received one five (ceftriaxone, ceftazidime, ticarcillin-clavulanic acid, imipenem-cilastatin, aztreonam) as therapy for infections. Quantitative examination stools was conducted at baseline, end antibiotic treatment, 1 week after...
To identify the roles of various antibiotics as risk factors for carbapenem-resistant extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae (KP) infection (ESBL-KP infection).Data were collected over 26 months in a tertiary care university hospital with established endemicity ESBL-KP (ESBL-CRKP). Using case-case-control design, patients who presented an caused by carbapenem-susceptible (ESBL-CSKP) and ESBL-CRKP compared common control group hospitalized patients. Effects...
Background: Assessing the overall burden of healthcare-associated infections (HAIs) is challenging, but imperative in evaluating cost-effectiveness infection control programs. This study aimed to estimate point prevalence and annual incidence HAIs Greece assess excess length stay (LOS) mortality attributable HAIs, for main sites tracer antimicrobial resistance (AMR) phenotypes pathogens. Patients methods: prevalent cohort used a nationally representative cross-section 8,247 inpatients 37...
Objective. To assess the feasibility and effectiveness of International Nosocomial Infection Control Consortium (INICC) multi-dimensional hand hygiene approach in 19 limited-resource countries to analyze predictors poor compliance. Design. An observational, prospective, cohort, interventional, before-and-after study from April 1999 through December 2011. The was divided into 2 periods: a 3-month baseline period 7-year follow-up period. Setting. Ninety-nine intensive care unit (ICU) members...
Building the European Antimicrobial Resistance Surveillance network in Veterinary medicine (EARS-Vet) was proposed to strengthen One Health antimicrobial resistance (AMR) surveillance approach.
A Knowledge, Attitudes and Practices (KAP) study was conducted at the end of May 2021 engaging 1456 healthcare workers (HCWs) from 20 hospitals throughout Greece. Acceptance vaccination against coronavirus disease 2019 (COVID-19) estimated 77.7%, with lower vaccine acceptance identified in nurses compared to physicians. Fears related safety, lack information general knowledge about vaccinations, influenza acceptance, education level years practice were among factors independently associated...
The activities of sparfloxacin, azithromycin, temafloxacin, and rifapentine against two virulent strains the Mycobacterium avium complex isolated from patients with AIDS were evaluated in a model intracellular infection compared that clarithromycin. Human monocyte-derived macrophages infected M. at day 6 culture. CFU was counted 60 min after inoculation. supernatant on days 4 7 concentrations used, which equal to peak levels serum, 10 micrograms per ml (MICs for strains, 16 micrograms/ml),...