- Nosocomial Infections in ICU
- Central Venous Catheters and Hemodialysis
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Surgical site infection prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Infective Endocarditis Diagnosis and Management
- Emergency and Acute Care Studies
- Bacterial biofilms and quorum sensing
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Clostridium difficile and Clostridium perfringens research
- Infections and bacterial resistance
- SARS-CoV-2 and COVID-19 Research
- Neutropenia and Cancer Infections
- Blood disorders and treatments
- Antibiotics Pharmacokinetics and Efficacy
- Surgical Sutures and Adhesives
- Healthcare Decision-Making and Restraints
- Enhanced Recovery After Surgery
- Infection Control in Healthcare
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Mycobacterium research and diagnosis
Centar za Promociju Nauke
2013-2023
Univerzitetski Klinički Centar Srbije
2006-2023
University of Belgrade
2021
Institut Sains dan Teknologi Al-Kamal
2006
Abstract Objective: Rates of ventilator-associated pneumonia (VAP) in low- and middle-income countries (LMIC) are several times above those high-income countries. The objective this study was to identify risk factors (RFs) for VAP cases ICUs LMICs. Design: Prospective cohort study. Setting: This conducted across 743 282 hospitals 144 cities 42 Asian, African, European, Latin American, Middle Eastern Participants: included patients admitted 24 years. Results: In total, 289,643 were followed...
To identify central-line (CL)-associated bloodstream infection (CLABSI) incidence and risk factors in low- middle-income countries (LMICs).From July 1, 1998, to February 12, 2022, we conducted a multinational multicenter prospective cohort study using online standardized surveillance system unified forms.The included 728 ICUs of 286 hospitals 147 cities 41 African, Asian, Eastern European, Latin American, Middle countries.In total, 278,241 patients followed during 1,815,043 patient days...
Fatigue, anxiety and depression are very frequent symptoms in patients with rheumatoid arthritis (RA).In this study we evaluated the influence of socioeconomic characteristics, therapy comorbidities on self-reported high fatigue, RA.Multicenter cross-sectional was performed 22 health institutions Serbia during period from April-August 2014 population older RA patients. Self-reported status measured by: Fatigue Assessment Scale, Patient Health Questionnaire-9 Generalized Anxiety Disorder-7....
Abstract Background: Short-term peripheral venous catheter–related bloodstream infection (PVCR-BSI) rates have not been systematically studied in resource-limited countries, and data on their incidence by number of device days are available. Methods: Prospective, surveillance study PVCR-BSI conducted from September 1, 2013, to May 31, 2019, 727 intensive care units (ICUs), members the International Nosocomial Infection Control Consortium (INICC), 268 hospitals 141 cities 42 countries Africa,...
Abstract Background As the only non-European Union (EU) country, Serbia participated in a second point prevalence survey of healthcare-associated infections (HAIs) and antimicrobial use (AMU) organized by European Centre for Disease Prevention Control (ECDC) EU countries. Here, we aimed to estimate HAI AMU patients who had recently undergone surgery compare risk profile, rates, among surgical non-surgical patients. Methods A national PPS was performed 65 Serbian acute-care hospitals,...
Vancomycin-resistant Enterococci (VRE) is one of the most important hospital pathogens. The aim study was to evaluate VRE colonization in patients hospitalized at Hematology Intensive Care Unit, as well associated risk factors. A prospective cohort involved 70 Unit (ICU), Clinic for Hematology, Clinical Center Serbia, Belgrade, during 3 months. Baseline demographic data, data about antibiotic usage and other factors present previous hospitalizations (within 6 months) were recorded each...
Millions of patients acquire healthcare-associated infections (HAIs) every year, putting them at risk for serious complications and prolonged hospitalization. Point prevalence surveys (PPS), guided by the European Centre Disease Prevention Control framework, are one primary methods which countries in Union conduct surveillance HAIs. Serbia, though not EU, implemented this approach its national PPS. The microbiological antimicrobial resistance (AMR) analyses comprised 61 out 65 hospitals...
INTRODUCTION: The results of numerous studies carried out over the last two decades have indicated that Acinetobacter spp. represents an increasingly important cause intrahospital infections (IHI). aim study was to determine potential differences in distribution individual risk factors between group patients whom multiresistant isolated and it not. MATERIAL AND METHODS: A prospective cohort 64 hospitalized with recorded IHI at University Hospital for Digestive Surgery, Clinical Center Serbia...
The aim of the present study was to provide first comprehensive analysis methicillin-resistant Staphylococcus aureus (MRSA) carriage among patients and healthcare workers (HCWs) in largest facility Serbia. Specimens from anterior nares obtained 195 hospitalized 105 HCWs were inoculated after broth enrichment onto chromogenic MRSA-ID medium. In total, 21 300 specimens yielded MRSA. Among patients, 7.7% colonized with MRSA, 5.7% Five out (23.8%) tested MRSA strains classified as...
Background/Aim. The risk for nosocomial infections (NIs) is 5-10 times higher in patients hospitalized the Intensive Care Units (ICUs) than staying other wards. incidence rates of NIs ICUs may be explained by fact that have more severe underlying disease, and are exposed to invasive diagnostic therapeutical procedures. unreasonable use antibiotics leads selection multiresistant agents, which been increasingly recorded as causative agents. aim this study was investigate characteristics period...
In this study the distribution of species and antimicrobial resistance among vancomycin resistant enterococci (VRE) recovered from clinical specimens obtained five hospitals in Belgrade was analyzed. Strains were further characterized by pulsed-field gel electrophoresis (PFGE). Polymerase chain reaction (PCR) used to investigate presence vanA vanB genes pathogenicity factor genes. Identification 194 VRE isolates revealed 154 Enterococcus faecium , 21 faecalis 10 raffinosus 9 gallinarum ....
Introduction/Aim. Intravascular device placement (IVD) is a part of everyday medical practice, however, its application associated with high risk onset nosocomial infections (NI) and increased mortality morbidity. Nosocomial blood (NBIs) account for 10% all the registered NI. NBIs are more frequent in patients placed IVD it present an important factor NBI, i.e. catheter-associated (CANBIs). Pathogenesis CANBIs complex conditioned by presence different characteristics related to catheter,...
Introduction: The emergence of organisms resistant to multiple antibiotics (MDRO) is a major public health problem in the twenty-first century all countries world. MDRO limits possibilities adequate antimicrobial treatment infections and increases morbidity, mortality healthcare costs institutions worldwide. Numerous studies indicate significant association between level antibiotic consumption frequency resistance. According data from Center for Disease Control Prevention (SDS) 2019, 2.8...
A fadiga, a ansiedade e depressão são sintomas muito frequentes em pacientes com artrite reumatoide (AR). Neste estudo, avaliou‐se influência de características socioeconômicas, tratamento comorbidades na elevação autorrelatadas AR. Este estudo transversal multicêntrico foi feito 22 instituições saúde Sérvia abril agosto 2014 população idosos O status autorrelatado dos medido pelos instrumentos Fatigue Assessment Scale, Patient Health Questionnaire‐9 Generalized Anxiety Disorder‐7. As...
INTRODUCTION: Nosocomial infections (NI) are significant medical problem in the countries worldwide. NI significance reflects higher morbidity and mortality rates, moreover, NIs add to longer stay treatment costs. Based on data obtained from underdeveloped developing countries, over 20% of hospitalized patients acquire some NIs, while that proportion is 5% developed countries. OBJECTIVE: a) establish frequency noosocomial at Clinic Digestive System Diseases, b) determine incidence accord...
Since the COVID-19 pandemic has started, Serbia faced problems in implementing proper public health measures population, including non-pharmaceutical interventions, as well protecting care workers (HCWs) from disease, like all other countries. This study aimed to estimate seroprevalence and evaluate risk perception of among HCWs three different hospitals Belgrade, Serbia: non-COVID hospital, Emergency Center (EC), dedicated COVID hospital.A cross-sectional was conducted during second wave...
Background: Surgical site infections (SSIs) and other healthcare related continues to be significant problem in surgical patients across the globe. Aim: To analyze compare surveillance data from large cohort of operated Clinic for Urology, Military Medical Academy Methods: A prospective study was performed identify incidence rate risk factors (SSI) 2010 2013. Infection control personal collected general about patients. The microbiologic testing at Institute Microbiology by routine methods....
Hospital-acquired infections (HAIs) are a global public health problem and put patients at risk of complications, including death. HAIs increase treatment costs, but their financial impact on Serbia's healthcare system is unknown. Our goal was to assess incremental costs in tertiary care adult intensive unit (ICU) that managed COVID-19 patients.A retrospective study from March 6th December 31st, 2020 included with microbiologically confirmed (positive rapid antigen test or real-time...
Upon admission, 7% of patients were already colonized with VRE. The rate VRE colonization during present hospitalization was 41.5%. Univariate logistic regression demonstrated statistical significant differences acute myeloid leukemia (AML) diagnosis (RR=3.1; 95%CI 1.1-8.6; p=0.03), length stay (RR=1.1; 1.1-1.2; p=0.002), use aminoglycosides (RR=3.9; 1.1-13.1; and pip/tazobactam (RR=4.7; 1.6-13.9; p=0.005) in hospitalization, duration carbapenem (RR=1.2; 1.1-1.3; p=0.05) (RR=1.4; 1.3-1.7;...
INTRODUCTION: Central venous catheter (CVC) placement is an unavoidable part of the everyday medical practice. At same time CVC application associated with high risk development central line-associated bloodstream infections (CLABSIs). These are cause icreased morbidity and mortality rates as well higer costs inpatient treatment2. Risk factors for onset CLABSIs include duration catheterization, length hospital stay before anatomic site placement, at intensive care units (ICU), parenteral...