A5081871424- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Nosocomial Infections in ICU
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Surgical site infection prevention
- Infective Endocarditis Diagnosis and Management
- Urinary Tract Infections Management
- Streptococcal Infections and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Colorectal Cancer Surgical Treatments
- Pneumonia and Respiratory Infections
- Antifungal resistance and susceptibility
- Infection Control in Healthcare
- Patient Satisfaction in Healthcare
- COVID-19 Clinical Research Studies
- Clostridium difficile and Clostridium perfringens research
- Pediatric Urology and Nephrology Studies
- Orthopedic Infections and Treatments
- Vibrio bacteria research studies
- Microscopic Colitis
- Long-Term Effects of COVID-19
Bellvitge University Hospital
2016-2025
Institut d'Investigació Biomédica de Bellvitge
2016-2025
Departament de Salut
2016-2025
Centro de Investigación Biomédica en Red
2022-2025
Instituto de Salud Carlos III
2016-2025
Reig Jofre (Spain)
2012-2025
Universitat de Barcelona
2012-2024
Servei de Salut de les Illes Balears
2024
Government of Catalonia
2024
Ajuntament de L’Hospitalet
2015-2023
Beginning in 1992, a sustained outbreak of multiresistant Acinetobacter baumannii infections was noted our 1,000-bed hospital Barcelona, Spain, resulting considerable overuse imipenem, to which the organisms were uniformly susceptible. In January 1997, carbapenem-resistant (CR) A. strains emerged and rapidly disseminated intensive care units (ICUs), prompting us conduct prospective investigation. It an 18-month longitudinal intervention study aimed at identification clinical microbiological...
ABSTRACT An outbreak due to extended-spectrum β-lactamase-producing Klebsiella pneumoniae (ESBL-KP) was detected from May 1993 June 1995. A total of 145 patients, particularly patients in intensive care units (ICUs) (107 [72%]), were colonized or infected. Infection developed 92 (63%) and primary bacteremia caused by ESBL-KP the most frequent infection (40 [43%]). single clone identified pulsed-field gel electrophoresis analysis throughout whole period, no molecular epidemiological...
For 16 years we prospectively observed 530 adult patients with brucellosis to analyze the characteristics of and risk factors for relapse. Clinical laboratory findings from 86 relapsed were milder during relapse episode when compared those same initial disease. Blood cultures positive Brucella melitensis in 65% cases ∼80% Risk that identified as being independently associated (by logistic regression analysis) "less-effective" antibiotic therapy (OR, 8.3; 95% CI, 4.6–15.1), blood disease 2.7;...
We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and endocarditis.
Antibiotic-induced modulation of the intestinal microbiota can lead to Clostridioides difficile infection (CDI), which is associated with considerable morbidity, mortality, and healthcare-costs globally. Therefore, identification markers predictive CDI could substantially contribute guiding therapy decreasing burden. Here, we analyze hospitalized patients at increased risk in a prospective, 90-day cohort-study before after antibiotic treatment diarrhea onset. We show that developing already...
<h3>Importance</h3> The consumption of broad-spectrum drugs has increased as a consequence the spread multidrug-resistant (MDR)<i>Escherichia coli</i>. Finding alternatives for these infections is critical, which some neglected may be an option. <h3>Objective</h3> To determine whether fosfomycin noninferior to ceftriaxone or meropenem in targeted treatment bacteremic urinary tract (bUTIs) due MDR<i>E <h3>Design, Setting, and Participants</h3> This multicenter, randomized, pragmatic, open...
Fecal colonization with multiresistant Acinetobacter baumannii was evaluated in 189 consecutive patients intensive care units (ICUs) during two different 2-month periods (October–November 1993 and May–June 1994). Rectal swabs were obtained weekly from admission to discharge the ICU. Overall, 77 (41%) had A. fecal colonization; detected 55(71%) of within first week their ICU stay. Clinical infections due occurred more frequently than those without (26% vs. S%, respectively; P < .001). The...
From 1988 to 1992, 27 of 855 cases Escherichia coli bacteremia in nonneutropenic adult patients observed at our hospital were due ciprofloxacin-resistant (CIPRO-R) strains. Eighteen episodes (67%) community acquired, and nine (33%) nosocomially acquired. Overall, the rates E. caused by CIPRO-R strains increased steadily from 0% 7.5% 1992 (P < 0.01). There was a statistically significant correlation between incidence upward trend fluoroquinolone (norfloxacin ciprofloxacin) use (r = 0.974;...
From March 1995 to 1997, sulbactam was prospectively evaluated in patients with non-life-threatening multiresistant Acinetobacter baumannii infections. During this period, 47 were treated sulbactam; of them, five excluded because they had received < or =48 h therapy. A total 42 patients, 27 males and 15 females a mean age 60+/-15 years, finally evaluated. Infections as follows: surgical wound, 19; tracheobronchitis, 12; urinary tract, 7; catheter-related bacteraemia, 2; pneumonia, 2....
Background. There is an urgent need for alternative rescue therapies in invasive infections caused by methicillin-resistant Staphylococcus aureus (MRSA). We assessed the clinical efficacy and safety of combination fosfomycin imipenem as therapy MRSA infective endocarditis complicated bacteremia.