A5026207220- Pneumonia and Respiratory Infections
- Antimicrobial Resistance in Staphylococcus
- Bacterial Infections and Vaccines
- Antibiotic Resistance in Bacteria
- Streptococcal Infections and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Bacterial Identification and Susceptibility Testing
- Infective Endocarditis Diagnosis and Management
- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Central Venous Catheters and Hemodialysis
- Respiratory viral infections research
- Antibiotics Pharmacokinetics and Efficacy
- Neonatal and Maternal Infections
- Influenza Virus Research Studies
- Bacterial biofilms and quorum sensing
- Microbial infections and disease research
- Sepsis Diagnosis and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Thyroid Disorders and Treatments
- Actinomycetales infections and treatment
- Otolaryngology and Infectious Diseases
- Patient Satisfaction in Healthcare
- Biosensors and Analytical Detection
Bellvitge University Hospital
2016-2025
Institut d'Investigació Biomédica de Bellvitge
2016-2025
Instituto de Salud Carlos III
2019-2025
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2015-2025
Centro de Investigación Biomédica en Red
2024-2025
Manufacturas Serviplast (Spain)
2025
Centre for Biomedical Network Research on Rare Diseases
2019-2024
Universitat de Barcelona
2012-2023
Centre de Recerca en Sanitat Animal
2018
Cegep de Saint Hyacinthe
2018
The aim of this study was to characterize the first two extended-spectrum cephalosporin-resistant and multidrug-resistant (MDR) Neisseria gonorrhoeae isolates collected from sexually related patients (men who have sex with men) in Spain. Antimicrobial susceptibility studied by Etest. Genes involved quinolone, ceftriaxone multidrug resistance were amplified PCR sequenced both directions. typed N. multi-antigen sequence typing (NG-MAST). had same MDR profile, showing penicillin (MIC 0.094...
<h2>Abstract</h2><h3>Objectives</h3> To assess the mortality attributable to infections caused by carbapenem-resistant Enterobacterales (CRE) and investigate effect of clinical management on differences in observed outcomes a multinational matched cohort study. <h3>Methods</h3> A prospective matched-cohorts study (NCT02709408) was performed 50 European hospitals from March 2016 November 2018. The main outcome 30-day with an active post-discharge follow-up when applied. CRE included patients...
Sir,Vancomycin is a commonly prescribed antibiotic for the treatment of severe Gram-positive infections and drug choice caused by MRSA. 1 Vancomycin cited as having potential to exacerbate myasthenia gravis, based upon reports neuromuscular blockade potentiation when
We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and endocarditis.
A prospective laboratory-based multicenter study that collected all adult invasive pneumococcal disease (IPD) episodes from 6 Spanish hospitals before (2008–2009) and after (2012–2013). The 13-valent conjugate vaccine (PCV13) licensure was conducted in order to analyze the impact of PCV13 introduction for children on IPD. total 1558 IPD were detected. incidence decreased significantly second period by -33.9% (95% CI, -40.3% -26.8%). due PCV7 serotypes (-52.7%; 95% -64.2% -37.5%) additional...
BackgroundCatheter-related bloodstream infections (CRBSI) are frequent healthcare-associated and an important cause of death.AimTo analyse changes in CRBSI epidemiology observed by the Infection Control Catalan Programme (VINCat).MethodsA cohort study including all hospital-acquired episodes diagnosed at 55 hospitals (2007-2019) Catalonia, Spain, was prospectively conducted. incidence rates were adjusted per 1,000 patient days. To assess rate trend year, negative binomial models used, with...
An increase in Streptococcus dysgalactiae subsp. equisimilis (SDSE) infections has been documented worldwide. This study aims to analyse invasive disease caused by SDSE (iSDSE) adults over an 11-year period Spain. We conducted a retrospective, laboratory-based of iSDSE detected at Hospital Universitari de Bellvitge (HUB) from 2012 2022 (n=89) and isolates collected three Spanish hospitals 2018 (n=22). Clinical data HUB was collected. Isolates were tested for antimicrobial susceptibility...
Invasive meningococcal disease (IMD) is associated with significant global morbidity and mortality addressed by conjugated polysaccharide subcapsular vaccines. In Spain, data on 4CMenB vaccine strain coverage antimicrobial susceptibility are limited. This study aimed to describe the genomic epidemiology, predict coverage, assess of 323 Neisseria meningitidis isolates causing IMD, collected from 57 Clinical Microbiology Laboratories in Spain over 12 years (2011/12-2022/23). Whole genome...
Most recently, a new rapid and fully automated electrochemiluminescence immunoassay for the determination of TSH receptor autoantibodies (TRAb) based on ability TRAb to inhibit binding human thyroid-stimulating monoclonal antibody (M22) has been established.To evaluate this assay system in clinical routine an international multicentre trial compare results with other established assays.Totally 508 Graves' disease (GD), 142 autoimmune thyroiditis, 107 subacute 109 nonautoimmune nodular...
ObjectiveTo analyse all cases of Nocardia pneumonia occurring between 2010 and 2016 in five Spanish hospitals.MethodsThis was a retrospective observational analysis clinical microbiological data collected from 55 pneumonia.ResultsThere were one to 20 per hospital six nine year. Chronic obstructive pulmonary disease, bronchiectasis, asthma the main predisposing underlying respiratory conditions. Thirty-four patients receiving systemic and/or inhaled corticosteroids prior infection, eight had...
Capsular switching allows pre-existing clones of Streptococcus pneumoniae expressing vaccine serotypes to escape the vaccine-induced immunity by acquisition capsular genes from pneumococci a non-vaccine serotype. Here, we have analysed clonal composition 492 clinical isolates serotype 11A causing invasive disease in Spain (2000–2012), and their ability evade host immune response. Antibiograms, serotyping molecular typing were performed. The restriction profiles pbp2x, pbp1a pbp2b also...
We analyzed the prevalence, etiology, and risk factors of culture-positive preservation fluid their impact on management solid organ transplant recipients.From July 2015 to March 2017, 622 episodes adult transplants at 7 university hospitals in Spain were prospectively included study.The prevalence was 62.5% (389/622). Nevertheless, only 25.2% (98/389) cases isolates considered "high risk" for pathogenicity. After applying a multivariate regression analysis, advanced donor age main...
The purpose of this study was to describe the presence novel optrA gene among clinical isolates enterococci in a Spanish teaching hospital (May 2016–April 2017). and cfr genes were screened by PCR all showing linezolid minimal inhibitory concentration (MIC) ≥4 mg/L. genetic relatedness isolates, resistance virulence genes, environment assessed whole-genome sequencing (WGS). Six 1,640 had MIC Among them, detected five Enterococcus faecalis isolated from unrelated patients. Although none them...
Abstract Urban wild boars (Sus scrofa) from Barcelona, Spain, harbor great diversity of Streptococcus suis strains, including strains with the cps2 gene and same molecular profile as local human cases. The increasing trend potential effective contacts for S. transmission is public health concern.
This study provides an update on invasive Haemophilus influenzae disease in Bellvitge University Hospital (2014–2019), reporting its evolution from a previous period (2008–2013) and analysing the non-typeable H. (NTHi) population structure using clade-related classification. Clinical data, antimicrobial susceptibility serotyping were studied compared with those of period. Population was assessed by multilocus sequence typing (MLST), SNP-based phylogenetic analysis The incidence remained...