Luca Fasano

ORCID: 0000-0003-2566-8552
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About
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Research Areas
  • Respiratory Support and Mechanisms
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Pleural and Pulmonary Diseases
  • Airway Management and Intubation Techniques
  • Spacecraft Design and Technology
  • Cardiac Arrest and Resuscitation
  • Sarcoidosis and Beryllium Toxicity Research
  • Medical Imaging and Pathology Studies
  • Asthma and respiratory diseases
  • Pulmonary Hypertension Research and Treatments
  • Lung Cancer Diagnosis and Treatment
  • Synthetic Aperture Radar (SAR) Applications and Techniques
  • Mechanical Circulatory Support Devices
  • Context-Aware Activity Recognition Systems
  • Indoor and Outdoor Localization Technologies
  • Tracheal and airway disorders
  • Respiratory and Cough-Related Research
  • Intensive Care Unit Cognitive Disorders
  • Remote-Sensing Image Classification
  • Satellite Image Processing and Photogrammetry
  • Long-Term Effects of COVID-19
  • Space exploration and regulation
  • COVID-19 Clinical Research Studies
  • Nosocomial Infections in ICU

Policlinico S.Orsola-Malpighi
2013-2022

University of Bologna
1996-2022

Agenzia Spaziale Italiana
2015-2022

University of Salento
2020-2022

Azienda USL di Bologna
2010-2021

Polytechnic University of Bari
2018

University of Rome Tor Vergata
2016

Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2015

International Society for Optics and Photonics
2015

Medica (Italy)
1996

To assess efficacy and safety of noninvasive ventilation-plus-extracorporeal Co2 removal in comparison to ventilation-only prevent endotracheal intubation patients with acute hypercapnic respiratory failure at risk failing ventilation.Matched cohort study historical control.Two academic Italian ICUs.Patients treated ventilation for due exacerbation chronic obstructive pulmonary disease (May 2011 November 2013).Extracorporeal CO2 was added when (arterial pH ≤ 7.30 arterial PCO2 > 20%...

10.1097/ccm.0000000000000607 article EN Critical Care Medicine 2014-09-17

AIMS--To evaluate whether endothelin-1 is involved in the pathology of idiopathic pulmonary fibrosis (IPF). METHODS--Plasma concentrations were evaluated 37 patients with IPF and 27 normal controls by radioimmunoassay. In addition, expression lung tissue was biopsy specimens obtained from four IPF. Three used as controls. Endothelin-1 immunoreactivity detected using immunohistochemistry. RESULTS--Elevated plasma found compared a positive correlation duration disease. No significant...

10.1136/jcp.48.4.330 article EN Journal of Clinical Pathology 1995-04-01

Purpose This study aimed to prospectively investigate 18F-FDG PET/CT role for the assessment of sarcoidosis activity and extension in comparison with thoracic high-resolution CT (HRCT) evaluate potential clinical impact findings. Secondary aim was changes cardiac FDG uptake related specific preparation before PET/CT. Methods We enrolled biopsy proven patients consecutively referred since January 2010. performed after a fat meal followed by 12-hour fasting compared HRCT results obtained...

10.1097/rlu.0b013e31827a27df article EN Clinical Nuclear Medicine 2013-02-21

The choice of the interface for noninvasive ventilation (NIV) is a key factor in NIV success. We hypothesised that new helmet specifically design to improve performance hypercapnic patients would be clinically equivalent standard oronasal mask. In multicentre, short-term, physiological, randomised trial chronic obstructive pulmonary disease facing an acute respiratory failure episode, we compared changes arterial blood gases (ABGs) and tolerance score obtained using or mask, and, as...

10.1183/09031936.00053814 article EN European Respiratory Journal 2014-12-10

BACKGROUND: A viral cause of idiopathic pulmonary fibrosis (IPF) was recently suggested by a Japanese study in which high prevalence anti-hepatitis C virus (HCV) antibodies detected. subsequent British failed to confirm these results. METHODS: Antibodies HCV were evaluated 60 patients with IPF, 130 non-interstitial lung disease, and 4614 blood donors. HCV-RNA genotypes the anti-HCV positive IPF. Anti-HCV ELISA confirmed recombinant immunoblotting assay (RIBA). detected reverse transcriptase...

10.1136/thx.51.3.315 article EN Thorax 1996-03-01

Interstitial lung diseases include different clinical entities with variable prognoses. Idiopathic pulmonary fibrosis (IPF), the most common, presents severe outcome (death within 3–5 y), whereas nonspecific interstitial pneumonia (NSIP) shows a more indolent progression. Preclinical evidence of somatostatin receptor (SSTR) expression on fibroblasts in vitro and murine models, coupled longer survival mice fibrotic lungs treated agents blocking SSTR, supports hypothesis imaging fibroblast...

10.2967/jnumed.110.079962 article EN Journal of Nuclear Medicine 2010-11-15

Persistent hypercapnia after COPD exacerbation is associated with excess mortality and early rehospitalization. High Flow Nasal cannula (HFNC), may be theoretically an alternative to long-term noninvasive ventilation (NIV), since physiological studies have shown a reduction in PaCO2 level few hours of treatment. In this clinical study we assessed the acceptability HFNC its effectiveness reducing patients recovering from Acute Hypercapnic Respiratory Failure (AHRF) episode. We also...

10.1186/s12890-020-1048-7 article EN cc-by BMC Pulmonary Medicine 2020-01-13

In this work we performed a comparison between two different approaches to track person in indoor environments using locating system based on BLE technology with smartphone and smartwatch as monitoring devices. To do so, provide the architecture designed describe how elements of proposed interact each other. Moreover, have evaluated system’s performance by computing mean percentage error detection position. Finally, present novel location prediction neural embeddings, soft-attention...

10.3390/s21144839 article EN cc-by Sensors 2021-07-15

The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum lower respiratory tract infections (LRTI), defined specific epidemiological, and microbiological aspects. A European network for ICU-related (ENIRRIs), supported the Respiratory Society, has been recently established, with aim at studying all infective episodes except community-acquired ones. multicentre, observational study is in progress, enrolling more than 1000 fulfilling clinical,...

10.1183/23120541.00092-2017 article EN cc-by-nc ERJ Open Research 2017-10-01

We report the case of pulmonary benign metastasizing leiomyoma in an asymptomatic 64-year-old woman who underwent hysterectomy for a uterine 26 years earlier. Routine chest radiograph revealed bilateral diffuse nodular opacities within lobes. Thoracic computed tomography (CT) scan showed peripheral lung nodules that do not display contrast enhancement. Positron emission (PET)-CT with 18F-fluorodeoxyglucose (18F-FDG PET-CT) demonstrated no significant metabolic activity nodules. The lesions...

10.1097/rti.0b013e31818a0840 article EN Journal of Thoracic Imaging 2009-02-01

<b><i>Background:</i></b> Few studies have reported a double-step follow-up of patients after hospitalization for COVID-19. <b><i>Objectives:</i></b> We designed an observational study with clinical, functional, and radiological evaluation at 2 6 months The primary outcome was to describe symptoms, spirometry, 6-minute walking test (6MWT) months. Secondary outcomes were identify if the lowest...

10.1159/000521316 article EN Respiration 2022-01-01

Worldwide there is an imbalance between the number of patients discharged after Covid-19 and availability healthcare resources to follow them acute illness. Six-minute walking test (6MWT) a valid inexpensive measure exercise capacity for people with chronic lung disease. We used 6MWT during follow-up verify if it can be reliable disease recovery. During we reported distance in meters (6MWD), lowest SpO2 when breathing air (SpO2 nadir), desaturation distance–saturation product (DSP), defined...

10.1183/13993003.congress-2021.oa4046 article EN 01.05 - Clinical respiratory physiology, exercise and functional imaging 2021-09-05
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