Chiara Mega

ORCID: 0000-0003-3206-3930
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About
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Research Areas
  • Respiratory Support and Mechanisms
  • Airway Management and Intubation Techniques
  • Cardiac Arrest and Resuscitation
  • Intensive Care Unit Cognitive Disorders
  • Nosocomial Infections in ICU
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Tracheal and airway disorders
  • Dysphagia Assessment and Management
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Pneumonia and Respiratory Infections
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • COVID-19 Prevention and Impact
  • Autoimmune and Inflammatory Disorders
  • Family and Patient Care in Intensive Care Units
  • Antibiotics Pharmacokinetics and Efficacy
  • Neonatal Respiratory Health Research
  • Neonatal and Maternal Infections
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cervical and Thoracic Myelopathy
  • Vagus Nerve Stimulation Research
  • Healthcare Quality and Satisfaction
  • Nerve Injury and Rehabilitation
  • Spinal Fractures and Fixation Techniques
  • Antibiotic Resistance in Bacteria

Policlinico S.Orsola-Malpighi
2008-2021

University of Bologna
2008-2021

Istituti di Ricovero e Cura a Carattere Scientifico
2021

Azienda USL di Bologna
2021

Informatics and Business Institute Darmajaya
2021

Istituto Ortopedico Rizzoli
2020

Tufts Medical Center
2015-2018

Azienda Ospedaliero-Universitaria Careggi
2017

The choice of the interface for noninvasive ventilation (NIV) is a key factor in NIV success. We hypothesised that new helmet specifically design to improve performance hypercapnic patients would be clinically equivalent standard oronasal mask. In multicentre, short-term, physiological, randomised trial chronic obstructive pulmonary disease facing an acute respiratory failure episode, we compared changes arterial blood gases (ABGs) and tolerance score obtained using or mask, and, as...

10.1183/09031936.00053814 article EN European Respiratory Journal 2014-12-10

Introduction: optimal treatment of Gram-negative infections in critically ill patients is challenged by changing pathophysiological conditions, reduced antimicrobial susceptibility and limited therapeutic options. The aim this study was to assess the impact maximizing Css/MIC ratio on efficacy continuous infusion (CI) meropenem treating documented perform a population pharmacokinetic/pharmacodynamic analysis support optimization. Materials Methods: Classification regression tree (CART) used...

10.3389/fphar.2021.781892 article EN cc-by Frontiers in Pharmacology 2021-12-08

To determine the effects of different tracheotomy tube sizes on diaphragm effort and weanability indices.Ten tracheotomized difficult to wean subjects were randomized 2 T-piece trials, with diameters: inner diameters 8 mm 6.5 mm. Diaphragm pressure-time product per min. (PTP(di/min)), lung compliance resistance (C(L) R(L)), breathing pattern, tension-time index (TT(di)), ratio frequency tidal volume (f/V(T)) recorded. In an in vitro model, flow-pressure relationship was measured using tubes...

10.4187/respcare.01747 article EN Respiratory Care 2012-05-21

The synergic combination of D-dimer (as proxy thrombotic/vascular injury) and static compliance parenchymal in predicting mortality COVID-19-ARDS has not been systematically evaluated. objective is to determine whether the elevated low can predict patients with COVID-19-ARDS. A “training sample” (March–June 2020) a “testing (September 2020–January 2021) adult invasively ventilated for were collected nine hospitals. first 24 h recorded. Study outcome was all-cause at 28-days. Cut-offs...

10.3390/biomedicines9091228 article EN cc-by Biomedicines 2021-09-15

<b>Rationale:</b> Administration of oxygen via mask or low flow nasal cannula is standard during breaks off NIV. HFNC an delivery system capable generating flows up to 60 l/min and FIO2 100%. <b>Aim:</b> To assess whether allows for longer NIV more beneficial than SO when <b>Methods:</b> Patients on due acute respiratory failure (ARF) were randomized (n=19) (n=21) Data collected at the end each session break, 6 breaks. <b>Results:</b> Baseline demographics comorbidities similar, except BMI...

10.1183/13993003.congress-2015.oa505 article EN 2015-09-01

Covid-19 merupakan penyakit pernapasan akut yang disebabkan oleh virus corona jenis baru. Penyakit ini pertama kali merebak di Wuhan, Cina lalu menyebar hampir ke seluruh dunia dan menyebabkan pandemi global. menyerang semua golongan, dewasa, lansia, maupun anak-anak. Semua lapisan masyarakat dari mulai dewasa hingga anak-anak perlu mendapatkan edukasi mudah dipahami mengenai Covid19 cara-cara pencegahannya. Hal menjadi dasar dilaksanakannya praktek kerja pengabdian IIB Darmajaya. Tujuan...

10.25077/logista.5.1.87-94.2021 article ID cc-by-nc LOGISTA - Jurnal Ilmiah Pengabdian kepada Masyarakat 2021-06-30

<b>Background:</b> Approaches to treat dyspnea in DNI patients include NIV, CPAP, and supplemental oxygen (SO). Limited data are available on physiological subjective responses each strategy. <b>Aim:</b> To assess the use, effects of NIV/CPAP monitor subjects' perspectives comparison oxygen. <b>Methods:</b> 124 consecutive dyspneic with order admitted at 3 study sites had variables recorded once daily (up 5 days). <b>Results:</b> 84 subjects received SO 40 were started NIV/CPAP. Baseline...

10.1183/1393003.congress-2017.pa1879 article EN 2017-09-01
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