A5027371207- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Transplantation: Methods and Outcomes
- Anesthesia and Pain Management
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- Anesthesia and Neurotoxicity Research
- Hemodynamic Monitoring and Therapy
- Nausea and vomiting management
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Spine and Intervertebral Disc Pathology
- Meta-analysis and systematic reviews
- Pneumonia and Respiratory Infections
- Organ Transplantation Techniques and Outcomes
- COVID-19 diagnosis using AI
- Nosocomial Infections in ICU
- Radiomics and Machine Learning in Medical Imaging
University of Padua
2015-2025
Azienda Ospedaliera di Padova
2016-2024
March of Dimes
2013-2023
VA Palo Alto Health Care System
2021
Stanford University
2021
Santa Maria Nuova Hospital
2018
University of Virginia Health System
2015
University of Virginia
2011-2013
American Heart Association
2013
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2013
In late December 2019 an outbreak of a novel coronavirus (SARS-CoV-2) causing severe pneumonia (COVID-19) was reported in Wuhan, Hubei Province, China. A common finding most COVID-19 patients is high D-dimer levels which are associated with worse prognosis. We aimed to evaluate coagulation abnormalities via traditional tests and whole blood thromboelastometry profiles group 22 (mean age 67 ± 8 years, M:F 20:2) consecutive admitted the Intensive Care Unit Padova University Hospital for acute...
Background Clinically used general anesthetics, alone or in combination, are damaging to the developing mammalian brain. In addition causing widespread apoptotic neurodegeneration vulnerable brain regions, exposure anesthesia at peak of synaptogenesis causes learning and memory deficiencies later life. vivo rodent studies have suggested that activation intrinsic (mitochondria-dependent) pathway is earliest warning sign neuronal damage, suggesting a disturbance mitochondrial integrity...
Abstract Background: General anesthetics induce apoptotic neurodegeneration in the developing mammalian brain. anesthesia (GA) also causes significant disturbances mitochondrial morphogenesis during intense synaptogenesis. Mitochondria are dynamic organelles that undergo remodeling via fusion and fission. The fine balance between these two opposing processes determines morphometric properties, allowing for their regeneration enabling normal functioning. As mitochondria exquisitely sensitive...
The American Society of Anesthesiologists physical status (ASA-PS) is a grading system adopted worldwide by anesthesiologists to classify the overall health patients. Its importance demonstrated not only its routinely use in clinical practice, but also deployment other healthcare-related environments. However, weak/moderate inter-observer agreement for ASA-PS has been previously shown and, although definitions and examples each class were provided ASA, doubts remain on individual factors...
Investigating the health-related quality of life (HRQoL) after intensive care unit (ICU) discharge is necessary to identify possible modifiable risk factors. The primary aim this study was investigate HRQoL in COVID-19 critically ill patients one year ICU discharge.
Abstract Purpose Erector spinae plane (ESP) block is an interfascial blockade used in different clinical scenarios. This study investigated the ventral extent of dye diffusion ESP block. Methods The ultrasound-guided was bilaterally performed with injection at T5 vertebral level (21-Gauge, 50 mm needle), using diluted black tissue marking (20 mL; 1:4 ratio standard saline solution) instead local anesthetic on two fresh-frozen corpses within body donation program University Padova....
Abstract Objectives Thrombin generation (TG) with and without thrombomodulin (TM) was evaluated in COVID-19 patients different disease severity thromboprophylaxis regimen, order to understand the prothrombotic profile. Methods We enrolled consecutive confirmed diagnosis of admitted Medical Departments (MD) or Intensive Care Units (ICU), 54 healthy controls. Results Eighty-nine were included (mean age 60.4±16.1 years, 68.5% male); 33.7% ICU. Twenty-four (26.9%) before administration; 45...
Despite thromboprophylaxis, patients with coronavirus disease 2019 (COVID-19) exhibit hypercoagulability and higher venous thromboembolic risk, although its real incidence is still unknown. The aim of this study was to evaluate the thromboembolism (VTE) in COVID-19 admitted both intensive care units (ICUs) medical wards (MWs). Consecutive for MW ICU at Padua University Hospital, all receiving underwent systematic ultrasonography internal jugular, upper lower limbs veins every 7 days (± 1...
Introduction Erector spinae plane (ESP) block is an emerging interfascial with a wide range of indications for perioperative analgesia and chronic pain treatment. Recent studies have focused their attention on mechanisms action ESP block. However, the pharmacokinetics drugs injected in is, as now, uninvestigated. The aim this brief report to investigate lidocaine series 10 patients. Methods We are reporting case patients undergoing bilateral multilevel lumbar spine surgery. was performed 3.5...
The risk of barotrauma associated with different types ventilatory support is unclear in COVID-19 patients. primary aim this study was to evaluate the effect respiratory strategies on occurrence; we also sought determine frequency and clinical characteristics patients who experienced complication.
A Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear an imminent saturation available ICU beds generated notion that rationing intensive care resources could have been necessary.In order to evaluate impact on capacity manage critically ill patients, we performed a retrospective analysis first 2 weeks (February 24-March 8). Data were collected from regional registries case report form sent participating sites. increased 1545 1989...
An increasing number of reports have described the COVID-19-associated pulmonary aspergillosis (CAPA) as being a further contributing factor to mortality. Based on recent consensus statement supported by international medical mycology societies, it has been proposed define CAPA possible, probable, or proven basis sample validity and thus diagnostic certainty. Considering current challenges associated with diagnoses, there is pressing need study epidemiology CAPA.We report incidence...