Stefano Muttini
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Airway Management and Intubation Techniques
- Tracheal and airway disorders
- Family and Patient Care in Intensive Care Units
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- COVID-19 and healthcare impacts
- Helminth infection and control
- Sepsis Diagnosis and Treatment
- Parasites and Host Interactions
- Traumatic Brain Injury and Neurovascular Disturbances
- Thermal Regulation in Medicine
- Neuroscience of respiration and sleep
- Pneumothorax, Barotrauma, Emphysema
- Electrolyte and hormonal disorders
- Olfactory and Sensory Function Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Vitamin C and Antioxidants Research
- Blood groups and transfusion
- Palliative Care and End-of-Life Issues
Ospedale San Carlo
2020-2024
Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
2020-2024
Policlinico S.Orsola-Malpighi
2020
Universidade do Sul de Santa Catarina
2019
Azienda Ospedaliera di Desio e Vimercate
2014-2016
IRCCS Ospedale San Raffaele
1999
University of Milan
1996
In December 2019, a novel coronavirus (severe acute respiratory syndrome 2 [SARS-CoV-2]) emerged in China and has spread globally, creating pandemic. Information about the clinical characteristics of infected patients who require intensive care is limited.To characterize with disease 2019 (COVID-19) requiring treatment an unit (ICU) Lombardy region Italy.Retrospective case series 1591 consecutive laboratory-confirmed COVID-19 referred for ICU admission to coordinator center (Fondazione IRCCS...
Importance Data on the association of COVID-19 vaccination with intensive care unit (ICU) admission and outcomes patients SARS-CoV-2–related pneumonia are scarce. Objective To evaluate whether is associated preventing ICU for to compare baseline characteristics vaccinated unvaccinated admitted an ICU. Design, Setting, Participants This retrospective cohort study regional data sets reports: (1) daily number administered vaccines (2) all consecutive in Lombardy, Italy, from August 1 December...
A Covid-19 outbreak developed in Lombardy, Veneto and Emilia-Romagna (Italy) at the end of February 2020. Fear an imminent saturation available ICU beds generated notion that rationing intensive care resources could have been necessary.In order to evaluate impact on capacity manage critically ill patients, we performed a retrospective analysis first 2 weeks (February 24-March 8). Data were collected from regional registries case report form sent participating sites. increased 1545 1989...
Abstract Background During the first coronavirus disease 2019 (COVID-19) pandemic wave, an unprecedented number of patients with respiratory failure due to a new, highly contagious virus needed hospitalization and intensive care unit (ICU) admission. The aim present study was describe communication visiting policies Italian units (ICUs) during COVID-19 wave national lockdown compare these data prepandemic conditions. Methods A web-based survey conducted among 290 hospitals. Each ICU (active...
ABO blood type A was reported to correlate with an increased risk of acute respiratory distress syndrome (ARDS) in white patients severe sepsis and major trauma compared other types. Information regarding phenotypes outcomes ARDS is unavailable. The primary aim determine the relationship between intensive care unit (ICU) mortality hypoxemic failure (AHRF). secondary describe association ICU length stay (LOS) this study population.In a multicenter, retrospective cohort study, we collected...
The aim of the present study is to detect presence SARS-CoV-2 patients affected by COVID-19 in olfactory mucosa (OM), sampled with nasal brushing (NB) and biopsy, assess whether a non-invasive procedure, such as NB, might be used large-scale procedure for demonstrating neuroepithelium. Nasal brushings obtained from all resulted positive immunocytochemistry while controls were negative. Double immunofluorescence showed that cells included supporting well neurons basal cells. OM biopsies an...
Herein, we report the effect of gold nanoparticles (AuNP) and n-acetylcysteine (NAC) isolated or in association as important anti-inflammatory antioxidant compounds on brain dysfunction septic rats. Male Wistar rats after sham operation caecal ligation perforation (CLP) were treated with subcutaneously injection AuNP (50 mg/kg) and/or NAC (20 saline immediately 12 h surgery. Twenty-four hours CLP, hippocampus prefrontal cortex obtained assayed for myeloperoxidase (MPO) activity, cytokines,...
BACKGROUND: Computed tomography (CT)-derived low muscle mass is associated with adverse outcomes in critically ill patients. Muscle ultrasound a promising strategy for quantitating mass. We evaluated the association between baseline rectus femoris cross-sectional area (RF-CSA) and intensive care unit (ICU) mortality. Secondary were determinants of RF-CSA, diagnostic performance RF-CSA after adjustment body size. METHODS: A prospective, single-center, observational cohort study was conducted...
The case of a 64-year-old man who was admitted to hospital with fever, general deterioration and anorexia is reported. For the past 4 years, patient had been receiving corticosteroid therapy for chronic inflammatory demyelinating polyradiculoneuropathy. Soon after admission developed respiratory insufficiency as result massive pneumonitis, severe hypoxia, acute anaemia, renal failure systemic response syndrome (SIRS) requiring Intensive Care Unit (ICU). All faecal, bronchial, duodenal urine...
The case of a 64-year-old man who was admitted to hospital with fever, general deterioration and anorexia is reported. For the past 4 years, patient had been receiving corticosteroid therapy for chronic inflammatory demyelinating polyradiculoneuropathy. Soon after admission developed respiratory insufficiency as result massive pneumonitis, severe hypoxia, acute anaemia, renal failure systemic response syndrome (SIRS) requiring Intensive Care Unit (ICU). All faecal, bronchial, duodenal urine...
Ever since coronavirus disease 2019 (COVID-19) was declared a global public health emergency, more than 60 million confirmed cases and one deaths have been recorded globally. Although most patients minimal flu-like symptoms, some of them develop severe pneumonia, which may lead to multi-organ failure death.1 Systemic hyperinflammation procoagulant state play major pathophysiological role in these forms.2 Autoimmune diseases are also characterized by inflammation often state, viruses be...