A5040166348- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- Cardiac Arrest and Resuscitation
- Reproductive tract infections research
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Nosocomial Infections in ICU
- Emergency and Acute Care Studies
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Sepsis Diagnosis and Treatment
- Urinary Tract Infections Management
- Intensive Care Unit Cognitive Disorders
- Pediatric health and respiratory diseases
- Heart Failure Treatment and Management
- Asthma and respiratory diseases
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- Antibiotic Resistance in Bacteria
- Airway Management and Intubation Techniques
- Family and Patient Care in Intensive Care Units
- COVID-19 and healthcare impacts
- Respiratory and Cough-Related Research
- Cholesterol and Lipid Metabolism
- Lipoproteins and Cardiovascular Health
Ospedale Papa Giovanni XXIII
2016-2025
University of Perugia
2024
Istituti di Ricovero e Cura a Carattere Scientifico
1997-2019
Policlinico San Matteo Fondazione
2019
Ospedale “M. Bufalini” di Cesena
2019
ASST Fatebenefratelli Sacco
2019
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2009-2018
IRCCS Policlinico San Donato
2018
Società Italiana di Medicina Generale
2017
Fondazione Salvatore Maugeri
2016
Abstract Background Severe COVID-19 is characterised by interstitial pneumonia and hyperinflammation, with elevated levels of pro-inflammatory cytokines, such as IL-6. Effective treatments are urgently needed, IL-6 a rational target to reduce hyperinflammation. Methods An observational, control cohort, single-centre study initiated at the Papa Giovanni XXIII Hospital in Bergamo, Italy included patients confirmed nasopharyngeal swab positive for severe acute respiratory syndrome coronavirus 2...
Recent reports suggest an association between Chlamydia pneumoniae and Helicobacter pylori bacteria atherosclerosis. We studied 51 patients (mean age, 68.3 years) who underwent abdominal aortic aneurysm surgery. For each patient we performed a microimmunofluorescence test for immunoglobulin G (IgG), IgA, IgM antibodies to C. specific antigen (TW-183). Anti-H. were determined by means of EIA-G test. Each surgical specimen was sampled into multiple sections 0.3 cm2 frozen at -20 degrees Two...
Not all risk factors for acquiring multidrug-resistant (MDR) organisms are equivalent in predicting pneumonia caused by resistant pathogens the community. We evaluated MDR bacteria patients coming from community who were hospitalized with pneumonia. Our evaluation was based on actual infection a pathogen and clinical outcome during hospitalization. An observational, prospective study conducted consecutive Data admission hospitalization collected. Logistic regression models used to evaluate...
Abstract Aims To investigate the efficacy and safety of early transition from hospital to ambulatory treatment in low-risk acute PE, using oral factor Xa inhibitor rivaroxaban. Methods results We conducted a prospective multicentre single-arm investigator initiated academically sponsored management trial patients with PE (EudraCT Identifier 2013-001657-28). Eligibility criteria included absence (i) haemodynamic instability, (ii) right ventricular dysfunction or intracardiac thrombi, (iii)...
<h3>Background</h3> Probabilistic scores have been recently suggested to identify pneumonia caused by multidrug-resistant (MDR) bacteria. The aim of the study was validate both Aliberti and Shorr in predicting MDR pneumonia, comparing them with healthcare associated (HCAP) classification. <h3>Methods</h3> Two independent European cohorts consecutive patients hospitalised were prospectively evaluated Barcelona, Spain (BC) Edinburgh, UK (EC). Data on admission during hospitalisation collected....
Abstract Objectives To evaluate the inter-rater agreement of chest X-ray (CXR) findings in coronavirus disease 2019 (COVID-19) and to determine value initial CXR along with demographic, clinical, laboratory data at emergency department (ED) presentation for predicting mortality need ventilatory support. Methods A total 340 COVID-19 patients who underwent ED setting (March 1–13, 2020) were retrospectively included. Two reviewers independently assessed abnormalities, including ground-glass...
Gender-related factors might affect vulnerability to Covid-19. The aim of this study was describe the role gender on clinical features and 28-day mortality in Covid-19 patients.
Respiratory infections precipitate wheezing in many asthmatic patients and may be involved the aetiopathogenesis of asthma. Several studies have demonstrated that viral provoke Bacterial seem to play a minor role. However, Chlamydia pneumoniae has been recently reported as possible cause The aim present study was evaluate role C. infection acute exacerbations asthma adults. Seventy four adult out-patients with diagnosis exacerbation were studied. Acute convalescent (> or = 3 weeks)...
Background.Findings from February, 2020, indicate that the clinical spectrum of Covid-19 can be heterogeneous, probably due to infectious dose and viral load SARS-CoV-2 within first weeks outbreak.The aim this study was investigate predictors overall 28-day mortality at peak Italian outbreak.Methods.Retrospective observational all patients admitted main hospital Bergamo, February 23 March, 14, 2020.Results.508 were hospitalized , predominantly male (72.4%), mean age 66±15 years; 49.2% older...
Abdominal aortic aneurysm tissue and peripheral blood mononuclear cells (PBMC) of 41 consecutive subjects undergoing abdominal surgery were analyzed by polymerase chain reaction (PCR) for the presence Chlamydia pneumoniae, Mycoplasma Helicobacter pylori DNA. Twenty patients (49%) positive C. pneumoniae DNA-16 (39%) in both PBMC tissue, 3 (7.3%) only, 1 (2.4%) artery specimen only. Previous exposure to was confirmed 19 (95%) 20 PCR pneumoniae-specific serology, using microimmunofluorescence...
Community-acquired pneumonia (CAP) severity scores can identify patients at low risk for mortality who may be suitable ambulatory care. Here, we follow the clinical course of hospitalized with CAP due to 2009 H1N1 influenza.To evaluate role as predictors mortality.This was a secondary data analysis influenza confirmed by reverse transcriptase polymerase chain reaction enrolled in CAPO (Community-Acquired Pneumonia Organization) international cohort study. PSI (Pneumonia Severity Index),...
Acute respiratory failure (ARF) and severe sepsis (SS) are possible complications in patients with community-acquired pneumonia (CAP). The aim of the study was to evaluate prevalence, characteristics, risk factors impact on mortality hospitalized CAP according presence ARF SS admission. This a multicenter, observational, prospective consecutive admitted three hospitals Italy, Spain, Scotland between 2008 2010. Three groups were identified: those neither nor (Group A), only B) both C) Among...
The choice of the interface for noninvasive ventilation (NIV) is a key factor in NIV success. We hypothesised that new helmet specifically design to improve performance hypercapnic patients would be clinically equivalent standard oronasal mask. In multicentre, short-term, physiological, randomised trial chronic obstructive pulmonary disease facing an acute respiratory failure episode, we compared changes arterial blood gases (ABGs) and tolerance score obtained using or mask, and, as...