David Jiménez
A5100653883- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Ultrasound in Clinical Applications
- Central Venous Catheters and Hemodialysis
- COVID-19 Clinical Research Studies
- Pulmonary Hypertension Research and Treatments
- Sepsis Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Diagnosis and Treatment of Venous Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Clinical practice guidelines implementation
- COVID-19 and healthcare impacts
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac tumors and thrombi
- Meta-analysis and systematic reviews
- Case Reports on Hematomas
- Obstructive Sleep Apnea Research
- Radiation Dose and Imaging
- Cardiovascular Effects of Exercise
- Long-Term Effects of COVID-19
- Cardiovascular and Diving-Related Complications
- Lung Cancer Diagnosis and Treatment
- Cardiac Arrhythmias and Treatments
Universidad de Alcalá
2016-2025
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2019-2025
Instituto Cajal
2015-2025
Universitat de Vic - Universitat Central de Catalunya
2025
Hospital Universitario Ramón y Cajal
2015-2024
Instituto Ramón y Cajal de Investigación Sanitaria
2015-2024
Instituto de Salud Carlos III
2019-2024
Rutgers, The State University of New Jersey
2023-2024
Escuela Nacional de Sanidad
2024
Universidad de Congreso
2024
Guidelines summarize and evaluate available evidence with the aim of assisting health professionals in proposing best management strategies for an individual patient a given condition. their recommendations should facilitate decision making daily practice. However, final decisions concerning must be made by responsible professional(s) consultation caregiver as appropriate.
There is considerable variation in disease behavior among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes 2019 (Covid-19). Genomewide association analysis may allow for identification of potential genetic factors involved development Covid-19.
The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial.In a randomized, double-blind trial, we compared tenecteplase plus heparin placebo normotensive embolism. Eligible had right ventricular dysfunction on echocardiography or computed tomography, as well myocardial injury indicated by positive test for cardiac troponin I T. primary outcome was death hemodynamic decompensation (or collapse) within 7 days after randomization. main safety...
The Pulmonary Embolism Severity Index (PESI) estimates the risk of 30-day mortality in patients with acute pulmonary embolism (PE). We constructed a simplified version PESI.The study retrospectively developed PESI clinical prediction rule for estimating derivation cohort Spanish outpatients. Simplified and original performances were compared cohort. underwent retrospective external validation an independent multinational (Registro Informatizado de la Enfermedad Tromboembólica [RIETE] cohort)...
<b>New @ESCardio Guidelines for the Diagnosis and Management of Acute #PulmonaryEmbolism developed in collaboration with @EuroRespSoc now available: #cardiotwitter @erspublications</b>http://bit.ly/2HnrJaj
Thrombotic events are commonly reported in critically ill patients with COVID-19. Limited data exist to guide the intensity of antithrombotic prophylaxis.To evaluate effects intermediate-dose vs standard-dose prophylactic anticoagulation among COVID-19 admitted intensive care unit (ICU).Multicenter randomized trial a 2 × factorial design performed 10 academic centers Iran comparing (first hypothesis) and statin therapy matching placebo (second hypothesis; not this article) adult ICU Patients...
The new, high-sensitivity troponin T (hsTnT) assay may improve risk stratification of normotensive patients with acute pulmonary embolism (PE). We externally validated the prognostic value hsTnT, and simplified Pulmonary Embolism Severity Index (sPESI), in a large multicenter cohort.We prospectively examined 526 PE; those, 31 (5.9%) had an adverse 30-day outcome. predefined hsTnT cutoff 14 pg/mL was associated high sensitivity negative predictive value, comparable to those sPESI. Both ≥14...
Rationale: Not all patients with acute pulmonary embolism (PE) have a high risk of an adverse short-term outcome.Objectives: This prospective cohort study aimed to develop multimarker prognostic model that accurately classifies normotensive PE into low and categories medical outcomes.Methods: The enrolled 848 outpatients from the PROTECT (PROgnosTic valuE Computed Tomography) (derivation cohort) 529 Prognostic Factors for Pulmonary Embolism (PREP) (validation cohort). Investigators assessed...
Abstract Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a preventable cause of in-hospital death, one the most prevalent vascular diseases. There lack knowledge with regards to contemporary presentation, management outcomes patients VTE. Many clinically important subgroups (including elderly, those recent bleeding pregnant patients) have been under-represented in clinical trials. Furthermore, design trials challenging some scenarios, such...
The aim of this study is to compare the Hestia rule vs. simplified Pulmonary Embolism Severity Index (sPESI) for triaging patients with acute pulmonary embolism (PE) home treatment.Normotensive PE 26 hospitals from France, Belgium, Netherlands, and Switzerland were randomized either or sPESI. They designated treatment if tool was negative physician-in-charge, taking into account patient's opinion, did not consider that hospitalization required. main outcomes 30-day composite recurrent venous...
The optimal treatment of intermediate-high-risk pulmonary embolism (PE) remains unknown.To assess the effect conventional catheter-directed thrombolysis (cCDT) plus anticoagulation vs monotherapy in improving echocardiographic measures right ventricle (RV) to left (LV) ratio acute PE.The Catheter-Directed Thrombolysis Anticoagulation Patients with Acute Intermediate-High-Risk Pulmonary Embolism (CANARY) trial was an open-label, randomized clinical patients PE, conducted 2 large...