Beatriz Muñoz
A5000113183- Reproductive tract infections research
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Parasitic Diseases Research and Treatment
- Cervical Cancer and HPV Research
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Syphilis Diagnosis and Treatment
- Hepatitis B Virus Studies
- Insects and Parasite Interactions
- COVID-19 Clinical Research Studies
- Adolescent Sexual and Reproductive Health
- Global Maternal and Child Health
- SARS-CoV-2 and COVID-19 Research
- Pneumonia and Respiratory Infections
- Gastrointestinal Bleeding Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Hepatitis Viruses Studies and Epidemiology
- Systemic Lupus Erythematosus Research
- Bacterial Infections and Vaccines
- Vector-borne infectious diseases
- Drug-Induced Hepatotoxicity and Protection
- Connexins and lens biology
- IgG4-Related and Inflammatory Diseases
Hospital Universitario Ramón y Cajal
2018-2025
Instituto Ramón y Cajal de Investigación Sanitaria
2018-2025
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2020-2025
Universidad de Alcalá
2018-2024
Johns Hopkins University
2005-2024
Johns Hopkins Medicine
1991-2024
Instituto de Salud Carlos III
2021-2022
Biogipuzkoa Health Research Institute
2020
Centro de Investigación Biomédica en Red
2020
Johns Hopkins Hospital
2013-2019
There is considerable variation in disease behavior among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes 2019 (Covid-19). Genomewide association analysis may allow for identification of potential genetic factors involved development Covid-19.
<h3>Objective</h3> To determine the causes of blindness and visual impairment in a population-based sample older Americans. <h3>Methods</h3> A random 3821 residents Salisbury, Md, between ages 65 84 years was identified from Medicare records. Sixty-six percent (2520 persons) agreed to undergo an eye examination; 26% participants were African American. The clinical examination included acuity testing with Early Treatment Diabetic Retinopathy Study chart standardized refraction for those worse...
Exposure to UV-B radiation in sunlight has been shown increase the risk of cataract formation high-risk occupational groups, but population not quantified.To determine ocular exposure for a older persons and association between lens opacities.The Salisbury Eye Evaluation project, population-based cohort adults.Salisbury, Md.A total 2520 community-dwelling 65-year-old 84-year-old adults Salisbury, Md, from 1993 1995, whom 26.4% were African Americans.Association photographically documented...
The effectiveness of commonly used procedures to correct trachomatous trichiasis the upper lid was examined in a clinical trial Oman. Lids were graded as having minor (five or fewer lashes), major (more than five and defective closure. Randomly allocated surgery specific for grade completed 384 lids, which 369 (96%) followed up once twice approximately 9 21 months after surgery. definition operative success included no evidence complete Tarsal rotation most effective operation successful 80%...
Background and Aims: In patients with non-severe acute or chronic autoimmune hepatitis (AIH) without cirrhosis, clinical practice guidelines recommend indistinct use of prednisone budesonide. However, budesonide is infrequently used in practice. We aimed to describe its compare efficacy safety as first-line options. Approach Results: This was a retrospective, multicenter study 105 naive AIH treated the drug. The control group included 276 prednisone. Efficacy assessed using logistic...
Baveno VII has defined a clinically significant (i.e., prognostically meaningful) decrease in liver stiffness measurement (LSM) cACLD as of ≥20% associated with final LSM <20 kPa or any to <10 kPa. However, these rules have not yet been validated against direct clinical endpoints.
Abstract Background and Aims Small series suggest that rituximab could be effective as treatment for autoimmune hepatitis (AIH), although data are scarce. We aimed to evaluate the efficacy safety of in different cohorts patients with AIH. Methods Multicentre retrospective analysis 35 AIH its variant forms treated included ColHai registry between 2015 2023. Results Most were female (83%), 10 (29%) had cirrhosis four (11.4%) Indication follows: 14(40%) refractory AIH, 19(54%) concomitant or...
Abstract Early maternal deprivation (MD) in rats (24 h, postnatal day 9–10) is a model for neurodevelopmental stress. There are some data proving that MD affects the endocannabinoid system (ECS) gender‐dependent manner, and these changes may account proposed schizophrenia‐like phenotype of rats. The impact on cannabinoid receptor distribution hippocampus unknown. aim this study to evaluate expression CB 1 2 receptors diverse relevant subregions (DG, CA1, CA3) 13‐day‐old by...
Lyme disease, the most common vector-borne infection in North America, is increasingly reported. When characteristic rash, erythema migrans, not recognized and treated, delayed manifestations of disseminated may occur. The accuracy diagnosis treatment early disease community unknown. A retrospective, consecutive case series 165 patients presenting for possible between August 1, 2002 2007 to a community-based referral practice Maryland. All had acute symptoms less than or equal 12 weeks...
We have analysed the long-term effects of adolescent (postnatal day 28–43) exposure male and female rats to nicotine (NIC, 1.4 mg/kg/day) and/or cannabinoid agonist CP 55,940 (CP, 0.4 on following parameters measured in adulthood: (1) memory ability evaluated object location task (OL) novel test (NOT); (2) anxiety-like behaviour elevated plus maze; (3) nicotinic CB 1 receptors cingulated cortex hippocampus. In OL, all pharmacological treatments induced significant decreases DI females,...
Background. Emerging evidence suggests that the mass distribution of azithromycin for trachoma control (MDA) may increase circulation macrolide resistance in bacteria associated with severe pediatric infections treated communities.
ABSTRACT Background Respiratory failure is a key feature of severe Covid-19 and critical driver mortality, but for reasons poorly defined affects less than 10% SARS-CoV-2 infected patients. Methods We included 1,980 patients with respiratory at seven centers in the Italian Spanish epicenters pandemic Europe (Milan, Monza, Madrid, San Sebastian Barcelona) genome-wide association analysis. After quality control exclusion population outliers, 835 1,255 population-derived controls from Italy,...
Around 750,000 patients per year will be cured of HCV infection until 2030. Those with compensated advanced chronic liver disease remain at risk for hepatic decompensation and de novo HCC. Algorithms have been developed to stratify early after cure; however, data on long-term outcomes the prognostic utility these stratification algorithms later time points are lacking. We retrospectively analyzed a cohort 2335 (liver stiffness measurement≥10 kPa) who achieved HCV-cure by interferon-free...
A cohort study was designed to assess the impact of mass distribution azithromycin (MDA) for trachoma control on incidence over six months pediatric diarrhea in eight communities rural Tanzania. single dose offered all residents four communities, where prevalence ≥ 10%. Four geographically matched had prevalences < 10% and did not receive MDA. All randomly selected children (n = 1036) were followed-up post-MDA with bi-weekly surveillance at home. In 0-1-month 1-3-month periods, MDA exposure...
Mass drug treatment with azithromycin (MDA) is part of the WHO-endorsed 'SAFE' strategy for trachoma control in endemic communities. MDA has been associated reduced prevalence and short-term reductions other bacterial infections, but can also lead to increased circulation macrolide-resistant bacteria.We prospectively monitored macrolide resistance fecal E. coli collected from young children participating PRET+ Study rural Tanzania. was administered four villages >10% prevalence. Four nearby...
This paper assesses the effects on adult Onchocerca volvulus of monthly doses ivermectin (150 µg/kg) given over 4, 8, and 12 months to patients in Guatemala. Nodules were removed 4 after last dose; O. extracted by collagenase digestion, studied histological techniques, compared with worms from untreated patients. Twelve killed a proportion (12% males 22% females), leaving remainder relatively unaffected females slowly resuming embryogenesis. After 8 doses, number female had resumed...
Background: We evaluated the effect of a single mass distribution azithromycin for trachoma on risk acute lower respiratory infection (ALRI) during 6-month period among young children living in 8 communities rural Tanzania. Methods: In communities, cohort randomly selected (n = 1036) was followed incidence ALRI episodes. Mass treatment using dose oral provided 4 where prevalence .10%. All were with biweekly surveillance at home 6 months. Incidence episodes calculated 0 to 1 month, 3 months,...