A5056521643- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Viral Infections and Immunology Research
- COVID-19 Clinical Research Studies
- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Liver Disease and Transplantation
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Cardiac Arrhythmias and Treatments
- COVID-19 and healthcare impacts
- Nutrition and Health in Aging
- Venous Thromboembolism Diagnosis and Management
- Mesenchymal stem cell research
- Infective Endocarditis Diagnosis and Management
- Potassium and Related Disorders
- Blood Pressure and Hypertension Studies
Shaheed Rajaei Cardiovascular Medical and Research Center
2015-2024
Iran University of Medical Sciences
2015-2024
Pediatric Oncology Group
2024
Al-Azhar University
2024
MedStar Union Memorial Hospital
2023-2024
MedStar Washington Hospital Center
2024
MedStar Health
2024
Lambung Mangkurat University
2023
National Heart Institute
2019
Northwestern University
2016-2018
Thrombotic events are commonly reported in critically ill patients with COVID-19. Limited data exist to guide the intensity of antithrombotic prophylaxis.To evaluate effects intermediate-dose vs standard-dose prophylactic anticoagulation among COVID-19 admitted intensive care unit (ICU).Multicenter randomized trial a 2 × factorial design performed 10 academic centers Iran comparing (first hypothesis) and statin therapy matching placebo (second hypothesis; not this article) adult ICU Patients...
Microvascular and macrovascular thrombotic events are among the hallmarks of coronavirus disease 2019 (COVID-19). Furthermore, exuberant immune response is considered an important driver pulmonary extrapulmonary manifestations COVID-19. The optimal management strategy to prevent thrombosis in critically-ill patients with COVID-19 remains unknown.
Abstract Background Thrombotic complications are considered among the main extrapulmonary manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration prophylactic antithrombotic therapy in these patients remain unknown. Methods This article reports final (90-day) results Intermediate versus Standard-dose Prophylactic anticoagulation In cRitically-ill pATIents with COVID-19: An opeN label randomized controlled trial (INSPIRATION) study. Patients COVID-19 admitted to...
Abstract Objective To assess the effect of statin treatment versus placebo on clinical outcomes in patients with covid-19 admitted to intensive care unit (ICU). Design INSPIRATION/INSPIRATION-S was a multicenter, randomized controlled trial 2×2 factorial design. Results for anticoagulation randomization have been reported previously. double blind atorvastatin are here. Setting 11 hospitals Iran. Participants Adults aged ≥18 years ICU. Intervention Atorvastatin 20 mg orally once daily...
Abstract Background Muscle wasting can be accelerated by chronic diseases such as heart failure and is one of the major causes disability, morbidity, mortality in this population. We aimed to investigate incidence muscle its associated factors dilated cardiomyopathy patients younger than 55 years age. Methods Between April 2014 December 2015, all symptomatic with a diagnosis non‐ischaemic who were referred clinic included our study. Dual energy X‐ray absorptiometry was used evaluate body...
Abstract Background and Aims Contemporary multicentre data on clinical diagnostic spectrum outcome in myocarditis are limited. Study aims were to describe baseline features, 1-year follow-up, predictors of clinically suspected or biopsy-proven (2013 European Society Cardiology criteria) adult paediatric patients from the EURObservational Research Programme Cardiomyopathy Myocarditis Long-Term Registry. Methods Five hundred eighty-one (68.0% male) patients, 493 adults, median age 38 (27–52)...
Abstract SARS‐CoV‐2 vaccines provide a safe solution with major impact on reducing the spread of virus and mild side effects. Research has shown rare cases myocarditis after mRNA vaccines. This study presents 29‐year‐old male chest pain 48 h receiving rAd26 rAd5 vector‐based COVID‐19 vaccine (Sputnik V vaccine). The electrocardiogram revealed ST‐segment elevation. Also, laboratory screening was remarkable for elevated cardiac Troponin‐I level, leukocytosis; echocardiography depicted severe...
Background: Myopericytoma is a rare, benign, slow-growing soft tissue tumor that developed from perivascular smooth muscle-like myoid cells (myopericytes) and shares features of both glomus muscle cells. It usually involves the skin tissues frequently affects extremities. characterized by concentric organization these oval-to spindle-shaped surrounding delicate vascular channels, displaying characteristic cell proliferation. Methods: A thirty-four-year-old male teacher Port Sudan City...
Abstract Objectives The present study assessed the changes in functional, biochemical, and echocardiographic measures following long‐term liothyronine therapy heart failure (HF) patients with low‐triiodothyronine (T3) syndrome (LT3S). Methods In placebo‐controlled, double‐blind study, adult clinically stable New York Heart Association functional class I–III systolic HF LT3S receiving standard were randomly assigned 1:1 to receive oral or placebo for 6 weeks. Low‐T3 was defined as a serum...
The coronavirus disease 2019 (COVID-19) pandemic has prompted the further virtualization of medical education. satisfaction level specific users such as cardiology residents with virtual education can augment its quality; hence, significance a valid and reliable questionnaire to obtain feedback is needed. This study aimed design measure validity reliability for during COVID-19 pandemic.In this cross-sectional study, self-administered was developed by faculty members Rajaie Cardiovascular...
The aim of the present study was to investigate whether vitamin D supplementation could improve biochemical findings and functional capacity patients with heart failure ( HF ). One hundred N ew Y ork H eart A ssociation NYHA ) class I through III were included in this prospective their 25‐hydroxyvitamin levels evaluated. Only 6% participants had a sufficient serum concentration 25( OH >30 nmol/L. Patients insufficient or deficient (<30 ng/ mL <20 , respectively) received oral 3...
Recent studies have introduced glucose intolerance and insulin resistance (IR) as novel risk factors in patients with pulmonary arterial hypertension (PAH).We aimed to investigate the prevalence of IR PAH their correlation functional capacity prognostic factors.Sixty-nine (class I Pulmonary accordance updated clinical classification hypertension) scheduled for right heart catheterization were enrolled. FBS, HbA1c, lipid profile, pro -BNP hs-CRP measured along a 6-minute walk test (6-MWT)...
Abstract The therapeutic potential of mesenchymal stem cells (MSCs) is out the question. Yet, recent drawbacks have resulted in a strategic shift towards application MSC-derived cell-free products such as extracellular vesicles (EVs). Recent reports revealed that functional properties MSCs, including EV secretion patterns, correlate with microenvironmental cues. These findings highlight urgent need for defining optimal circumstances preparation. Considering limitations primary cells, we...
The authors studied the relationship between liver function tests and serum uric acid level with clinical hemodynamic profiles in heart failure. Fifty patients (aged 44±15 years; 74.5% men) an ejection fraction (EF) <35% were enrolled assessment was performed. Hemodynamic indices (including pulmonary arterial pressure [PAP], capillary wedge [PCWP], cardiac index by standard Edwards Lifesciences Swan-Ganz catheters, measured simultaneously. age- sex-matched controls normal EF also studied. A...
Sildenafil is a selective phosphodiesterase‐5 inhibitor and causes vasodilatation, particularly in pulmonary circulation. Since left heart failure may be associated with hypertension “out of proportion to disease,” sildenafil have beneficial effect such patients. The present investigation was designed as 12‐week, single‐center, randomized, double‐blind, placebo‐controlled study evaluating the effects on mean blood pressure (primary endpoint) patients systolic failure. Secondary endpoints...
We sought to evaluate the regional longitudinal strain/strain rate profiles in right atrial wall quantify function systolic heart failure patients.According previous studies on deformational properties of left atrium, strain and rates represent reservoir early late diastolic show conduit booster functions, respectively.Thirty patients with a diagnosis (left ventricular ejection fraction < or = 35%) scheduled for catheterization were enrolled. Echocardiography was performed obtain deformation...
Heart failure (HF) is a growing public health concern as consequence of the ageing population and improved survival patients with HF. HF defined impaired organ perfusion and/or high filling pressure. It systemic chronic disease such involves many organs, not least liver kidney. The complex vascular system its metabolic activity render it vulnerable to circulation disturbances trigger molecular haemodynamic changes in patients. There are studies describing impact on patient outcomes. Hepatic...
Heart failure is the biggest cause of mortality and morbidity in people with thalassemia, iron deposition cardiac tissue impairs cardiovascular function. Therefore, early detection involvement important to improve prognosis these individuals.Two- three-dimensional echocardiography was performed evaluate left ventricular ejection fraction (LVEF), volumes diameters, global longitudinal strain (GLS) 130 individuals β-thalassemia using speckle tracking method. Magnetic resonance imaging (MRI)...
Pheochromocytoma is a rare, catecholamine-secreting tumor of neuroendocrine cells. It has been documented to present atypically as myocardial ischemia, arrhythmias, or congestive heart failure. We the case patient who had transient cardiomyopathy with hypokinesia basal portions left ventricle and hyperkinesia apex triggered by pheochromocytoma crisis similar that tako-tsubo cardiomyopathy, but an inverse ventricular contractile pattern ('inverted tako-tsubo'). (Cardiol J 2012; 19, 5: 527-531)