A5059807691- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Pain Management and Treatment
- Cardiac Structural Anomalies and Repair
- Pain Mechanisms and Treatments
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Musculoskeletal pain and rehabilitation
- Moyamoya disease diagnosis and treatment
- Cardiovascular Syncope and Autonomic Disorders
- Vascular anomalies and interventions
- Healthcare cost, quality, practices
- Cardiac Health and Mental Health
- Coronary Artery Anomalies
- Chemotherapy-induced cardiotoxicity and mitigation
- Corneal Surgery and Treatments
- Cardiovascular Issues in Pregnancy
- Aortic Disease and Treatment Approaches
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Neurosurgical Procedures and Complications
Iran University of Medical Sciences
2021-2025
Shaheed Rajaei Cardiovascular Medical and Research Center
2020-2025
Tehran University of Medical Sciences
2010-2017
Imam Khomeini Hospital
2017
Thrombotic events are commonly reported in critically ill patients with COVID-19. Limited data exist to guide the intensity of antithrombotic prophylaxis.To evaluate effects intermediate-dose vs standard-dose prophylactic anticoagulation among COVID-19 admitted intensive care unit (ICU).Multicenter randomized trial a 2 × factorial design performed 10 academic centers Iran comparing (first hypothesis) and statin therapy matching placebo (second hypothesis; not this article) adult ICU Patients...
Microvascular and macrovascular thrombotic events are among the hallmarks of coronavirus disease 2019 (COVID-19). Furthermore, exuberant immune response is considered an important driver pulmonary extrapulmonary manifestations COVID-19. The optimal management strategy to prevent thrombosis in critically-ill patients with COVID-19 remains unknown.
Abstract Background Thrombotic complications are considered among the main extrapulmonary manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration prophylactic antithrombotic therapy in these patients remain unknown. Methods This article reports final (90-day) results Intermediate versus Standard-dose Prophylactic anticoagulation In cRitically-ill pATIents with COVID-19: An opeN label randomized controlled trial (INSPIRATION) study. Patients COVID-19 admitted to...
Abstract Objective To assess the effect of statin treatment versus placebo on clinical outcomes in patients with covid-19 admitted to intensive care unit (ICU). Design INSPIRATION/INSPIRATION-S was a multicenter, randomized controlled trial 2×2 factorial design. Results for anticoagulation randomization have been reported previously. double blind atorvastatin are here. Setting 11 hospitals Iran. Participants Adults aged ≥18 years ICU. Intervention Atorvastatin 20 mg orally once daily...
Background Obstruction within the left anterior descending coronary artery (LAD) is prevalent, serving as a prominent and independent predictor of mortality. Invasive Fractional flow reserve (FFR) gold standard for Coronary Artery Disease risk assessment. Despite advances in computational imaging techniques, no definitive methodology currently assures clinicians reliable, non-invasive strategies future planning. Method The present research encompassed cohort 150 participants who were...
Abstract Coronary artery disease is the leading global cause of mortality and Fractional Flow Reserve (FFR) widely regarded as gold standard for assessing coronary stenosis severity. However, due to limitations invasive FFR measurements, there a pressing need highly accurate virtual calculation framework. Additionally, it’s essential consider local haemodynamic factors such time-averaged wall shear stress (TAWSS), which play critical role in advancement atherosclerosis. This study introduces...
To assess main indications, postoperative complications and clinicopathological correlation of ocular enucleation-evisceration.A total 107 subjects who underwent enucleation and/or evisceration received hydroxyapatite implants (Scleral wrap or mesh) were assessed. For each patient data was collected which included demographic information, clinical history, primary diagnosis, cause ophthalmic surgery (traumatic, non-traumatic), type surgical procedure (enucleation, evisceration) pathological...
Background In the INSPIRATION-S trial, atorvastatin versus placebo was associated with a nonsignificant 16% reduction in 30-day composite of venous/arterial thrombosis or death intensive care unit (ICU) patients COVID-19. Thrombo-inflammatory response coronavirus disease 2019 (COVID-19) may last beyond first 30 days. Methods This article reports effects 20 mg daily on 90-day clinical and functional outcomes from INSPIRATION-S, double-blind multicenter randomized trial adult ICU The main...
Abstract BACKGROUND: The purpose of this study is to investigate the relationship between mean heart dose received in left breast cancer radiation therapy and cardiac injury as measured by Pro-BNP Troponin laboratory levels ventricular systolic function, LVEF GLS echocardiography. METHOD: This research was carried out at Omid Hospital, Isfahan City, Iran, using before after intervention single-arm approach on a population patients diagnosed with who for 2021- 2022. Troponin, Pro-BNP, GLS,...
Most cases of congenital coronary artery fistula (CAF) resolve spontaneously, symptomatic patients with severe shunting require surgical intervention. Our aim is to evaluate success rate and outcome CAFs treatment using transcatheter interventional methods.This retrospective study conducted on 28 CAF who were referred Rajaie Cardiovascular Medical Research Center in Tehran between 2015 2020. Baseline characteristics collected by assessing hospital records, followed up annually for long-term...
Background: Patients' hesitation to seek medical care has seriously compromised the management of acute coronary syndrome during coronavirus disease 2019 (COVID-19) outbreak. In present study, we have reported rate discharged against advice (DAMA) among patients referred chest pain unit (CPU) a tertiary cardiovascular center and compared their clinical outcomes with whom admitted or managed conservatively. Methods: Patients modified HEART risk score ≥4 CPU were included in study. Population...
Background: Prosthetic valve thrombosis is of the serious long-term complications heart replacement that its treatment particularly in left-sided valves controversial. Both surgery and thrombolysis are associated with their own merits drawbacks. Hence, aim present study evaluation response to thrombolytic therapy patients aortic prosthetic a tertiary center Tehran, Iran, during 2007–2019. Materials Methods: In this retrospective study, 85 (including 63 case 22 therapy) were evaluated....
Background: As an advanced generation of flow diverters (FD), pipeline embolization device (PED) is introduced for endovascular aneurysm occlusion. In the present study, we aimed to mid-term results after treatment unruptured intracranial aneurysms using PED. Patients and Methods: A total 20 patients with wide neck were treated PED between July October 2010. followed up 4 8 months procedure. Digital subtraction angiography (DSA) was carried out assess stent integrity, displacement, presence...
Infective endocarditis can cause several major complications, including valvular destruction, aneurysm formation, and aortic ring abscesses, pseudoaneurysm formation in left ventricular outflow tract (LVOT) is quite a rare complication of infective endocarditis. Here, we present case which had two simultaneous LVOT pseudoaneurysms, bicuspid valve (BAV) abscess along with the presence anerobic bacteria (Peptostreptococcus) tissue culture. We describe echocardiographic, computed tomography...