A5086270825- Viral Infections and Immunology Research
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Particle Detector Development and Performance
- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- Diamond and Carbon-based Materials Research
- High-Energy Particle Collisions Research
- Cardiac Imaging and Diagnostics
- Cardiac Structural Anomalies and Repair
- Ion channel regulation and function
- Pericarditis and Cardiac Tamponade
- Eosinophilic Disorders and Syndromes
- SARS-CoV-2 and COVID-19 Research
- Systemic Sclerosis and Related Diseases
- Systemic Lupus Erythematosus Research
- Infective Endocarditis Diagnosis and Management
- Atomic and Subatomic Physics Research
- Cardiovascular Syncope and Autonomic Disorders
- Medical Imaging Techniques and Applications
- Nuclear Structure and Function
Vita-Salute San Raffaele University
2015-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2018-2024
IRCCS Ospedale San Raffaele
2008-2024
University of Milan
1992-2023
Genome and Company (South Korea)
2023
Presidio Ospedaliero
2023
Accademia Italiana Medicina Osteopatica
2023
University of Brescia
2023
Ospedale Maggiore
2023
We conducted a randomized, controlled trial of circumferential pulmonary-vein ablation for the treatment chronic atrial fibrillation.A total 146 patients with mean (+/-SD) age 57+/-9 years who had fibrillation were randomly assigned to receive amiodarone and undergo two cardioversions during first three months alone (the control group) or in combination ablation. Cardiac rhythm was assessed daily telephonic transmissions one year. The left diameter severity symptoms at 12 months.Among 77...
Acute myocarditis (AM) is thought to be a rare cardiovascular complication of COVID-19, although minimal data are available beyond case reports. We aim report the prevalence, baseline characteristics, in-hospital management, and outcomes for patients with COVID-19-associated AM on basis retrospective cohort from 23 hospitals in United States Europe.A total 112 suspected 56 963 hospitalized COVID-19 were evaluated between February 1, 2020, April 30, 2021. Inclusion criteria hospitalization...
Circumferential pulmonary vein ablation (CPVA) is effective in curing atrial fibrillation (AF), but new-onset left tachycardia (AT) a potential complication. We evaluated whether modified CPVA approach including additional lines on posterior wall and the mitral isthmus would reduce incidence of AT after PV ablation.A total 560 patients (291 men, 52%; age, 56.5+/-7.3 years) entered study; 280 were randomized to alone (group 1) 2). The primary end point was freedom from procedure. In group 1,...
Ventricular fibrillation can be the presenting arrhythmia in children with asymptomatic Wolff–Parkinson–White syndrome. Deaths due to this are potentially preventable.
Background— The aim was to relate distinct scar distributions found in nonischemic cardiomyopathy with ventricular tachycardia (VT) morphology, late potential distribution, ablation strategy, and outcome. Methods Results— Eighty-seven patients underwent catheter for drug-refractory VT. Based on endocardial unipolar voltage, 44 were classified as predominantly anteroseptal 43 inferolateral. Anteroseptal more frequently fulfilled diagnostic criteria dilated (64% versus 36%), associated...
Successful late potential (LP) abolition and postprocedural ventricular tachycardia (VT) noninducibility constitute significant end points after catheter ablation for VT. We investigated the prognostic impact of a combined procedural point VT LP in large series post-myocardial infarction patients with VT.A total 160 (154 men, 94% implantable cardioverter defibrillators) consecutive undergoing first-time procedures from 2010 to 2012 were included. Of 159 surviving procedure, 137 (86%) either...
The Cardiomyopathy Registry of the EURObservational Research Programme is a prospective, observational, and multinational registry consecutive patients with four cardiomyopathy subtypes: hypertrophic (HCM), dilated (DCM), arrhythmogenic right ventricular (ARVC), restrictive (RCM). We report baseline characteristics management adults enrolled in registry. A total 3208 were by 69 centres 18 countries [HCM (n = 1739); DCM 1260); ARVC 143); RCM 66)]. Differences between subtypes (P < 0.001)...
Progressive multifocal leukoencephalopathy (PML) remains a frequent and life-threatening complication of human immunodeficiency virus (HIV) infection in the era highly active antiretroviral therapy (HAART). Although one-half patients with this disease will survive, outcome is unpredictable at diagnosis, prognostic markers are needed.JC (JCV) DNA levels were measured cerebrospinal fluid (CSF) samples obtained from 61 HIV-infected PML, including 38 who treated HAART 23 did not receive HAART,...
<h3>Objectives:</h3> Our aim was to conduct a comparative study in large cohort of myopathic patients carrying <i>LMNA</i> gene mutations evaluate clinical and molecular features associated with different phenotypes. <h3>Methods:</h3> We performed retrospective 78 mutation 30 familial cases without muscle involvement. analyzed characterizing the various forms <i>LMNA</i>-related myopathy through correlation statistics. <h3>Results:</h3> Of patients, 37 (47%) had limb-girdle muscular...
The mechanism of cardiac resynchronization therapy (CRT)-induced proarrhythmia remains unknown. We postulated that pacing from a left ventricular (LV) lead positioned on epicardial scar can facilitate re-entrant tachycardia. aim this study was to investigate the relationship between CRT-induced and LV location within scar.Twenty-eight 63 endocardial maps, obtained 64 CRT patients undergoing tachycardia ablation, were analyzed. A positive lead/scar relationship, defined as tip scar/border...
No studies investigated the prevalence of arrhythmias among clinically-stable patients affected by COVID-19 infection.We assessed prevalence, type, and burden arrhythmias, a single-day snapshot in seven non-intensive COVID Units at third-level center.We enrolled 132 inhospital (mean age 65±14y; 66% males) newly diagnosed with infection. Arrhythmic episodes were detected 12 (9%). In detail, 8 had atrial fibrillation, 4 self-limiting supraventricular tachyarrhythmias. There no cases...