- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Sports injuries and prevention
- Sepsis Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Congenital Heart Disease Studies
- BRCA gene mutations in cancer
- Viral Infections and Immunology Research
- Transplantation: Methods and Outcomes
- Trauma and Emergency Care Studies
- Cardiovascular Syncope and Autonomic Disorders
- Venous Thromboembolism Diagnosis and Management
- Ion channel regulation and function
- Genetic Neurodegenerative Diseases
- ECG Monitoring and Analysis
Inserm
2013-2024
Sorbonne Université
2016-2024
Assistance Publique – Hôpitaux de Paris
2015-2024
University of Iowa Hospitals and Clinics
2024
Pitié-Salpêtrière Hospital
2016-2022
Laboratoire Informatique d'Avignon
2022
Hospital Universitario Virgen de la Arrixaca
2022
Centro de Investigación en Red en Enfermedades Cardiovasculares
2022
Universidad de Murcia
2022
Ludwig-Maximilians-Universität München
2021-2022
Survival after out-of-hospital cardiac arrest (OHCA) remains disappointingly low. Among patients admitted alive, early prognostication challenging. This study aims to establish a stratification score for in intensive care unit (ICU) OHCA, according their neurological outcome.The CAHP (Cardiac Arrest Hospital Prognosis) was developed from the Sudden Death Expertise Center registry (Paris, France). The primary outcome poor defined as Cerebral Performance Category 3, 4, or 5 at hospital...
The Cardiomyopathy Registry of the EURObservational Research Programme is a prospective, observational, and multinational registry consecutive patients with four cardiomyopathy subtypes: hypertrophic (HCM), dilated (DCM), arrhythmogenic right ventricular (ARVC), restrictive (RCM). We report baseline characteristics management adults enrolled in registry. A total 3208 were by 69 centres 18 countries [HCM (n = 1739); DCM 1260); ARVC 143); RCM 66)]. Differences between subtypes (P < 0.001)...
The interaction between common cardiovascular risk factors (CVRF) and hypertrophic cardiomyopathy (HCM) is poorly studied. We sought to explore the relation CVRF clinical characteristics of patients with HCM enrolled in EURObservational Research Programme (EORP) Cardiomyopathy registry.1739 were hypertension (HT), diabetes (DM), body mass index (BMI), traits was analysed. Analyses stratified according presence or absence a pathogenic variant sarcomere gene. prevalence HT, DM, obesity (Ob)...
Background Holter analysis requires significant clinical resources to achieve a high-quality diagnosis. This study sought assess whether an artificial intelligence (AI)-based platform using deep neural networks is noninferior conventional one used in routine detecting major rhythm abnormality. Methods and Results A total of 1000 (24-hour) recordings were collected from 3 tertiary hospitals. Recordings independently analyzed by cardiologists for the AI-based electrophysiologists as part...
Introduction Twenty‐five to 32% of patients with synovial sarcoma (SS) relapse after appropriate treatment, and experience a poor outcome. Patients who can be salvaged by second‐line therapy need more clearly identified. Methods Data treated in SFCE ( Société Française des Cancers de l'Enfant ) centers an initial diagnosis localized SS before the age 18 years from 1/1988 12/2008, experienced at least one relapse, were retrieved. After descriptive analysis, statistical analysis was performed...
Predictive genetic testing (PGT) is offered to asymptomatic relatives at risk of hereditary heart disease, but the impact result disclosure has been little studied. We evaluated psychosocial impacts PGT in using self-report questionnaires (including State-Trait Anxiety Inventory) 517 adults, administered three times prospective cohort (PCo: n = 264) and once retrospective (RCo: 253). The main motivations for undergoing were “to remove doubt” “for their children”. level anxiety increased...
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited associated with a high risk of arrhythmia (VA). Current guidelines recommend beta-blockers as first-line medical therapy and if ineffective, sotalol or amiodarone. We describe our experience, tertiary centre for ARVC, the effectiveness tolerance flecainide in addition to prevent VA ARVC.We retrospectively included 100 consecutive ARVC patients who received between May 1999 November 2017. Treatment persistence related side...
Diagnosis of short QT syndrome (SQTS) remains difficult in case borderline values as often found normal populations. Whether some shortening refractory periods (RP) may help differentiating SQTS from subjects is unknown.
Background: Friedreich’s ataxia (FA) is a rare autosomal recessive mitochondrial disease resulting of triplet repeat expansion guanine-adenine-adenine (GAA) in the frataxin (FXN) gene, exhibiting progressive cerebellar ataxia, diabetes and cardiomyopathy. We aimed to determine relationship between cardiac biomarkers, serum N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity troponin (hsTnT) concentrations, extent genetic abnormality parameters. Methods: Between 2013 2015,...